Immunohistochemical and serological evidence for the role of streptococcal proteinase in acute post-streptococcal glomerulonephritis

Kidney International

Volumn 54, Issue 3, 1998, Pages 819-826

  Cu, G A ^a   Mezzano, S ^a   Bannan, J D ^a   Zabriskie, J B ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Immune complex mediated disease; Infection; Nephritis; Nephritogenic protein; Plasmin; Streptococcal pyrogenic exotoxin B; Toxin

Indexed keywords

BACTERIUM ANTIBODY; EXOTOXIN; PROTEINASE; PYROGEN;

ADOLESCENT; ALLERGIC GLOMERULONEPHRITIS; ANTIBODY TITER; ARTICLE; CHILD; CLINICAL ARTICLE; COMPLEMENT ACTIVATION; CONTROLLED STUDY; ENZYME RELEASE; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOGENESIS; IMMUNOREACTIVITY; KIDNEY BIOPSY; PRIORITY JOURNAL; RHEUMATIC FEVER; SCARLET FEVER; SERODIAGNOSIS; STREPTOCOCCUS GROUP A; TISSUE DISTRIBUTION;

EID: 0031684402     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1998.00052.x     Document Type: Article

References (34)

1. R. Poon-King J. Bannan A. Viteri G. Cu J.B. Zabriskie Identification of an extracellular plasmin binding protein from nephritogenic streptococci J Exper Med 178 1993 759 763
2. S.D. Elliott A proteolytic enzyme produced by Group A streptococci with special reference to its effect on the type-specific M antigen J Exp Med 81 1945 573 592
3. T.Y. Liu Demonstration of the presence of a histidine residue at the active site of streptococcal proteinase J Biol Chem 242 1967 4029 4032
4. A.R. Hauser D.L. Stevens E.L. Kaplan P.M. Schlievert Molecular analysis of pyrogenic exotoxins from Streptococcus pyogenes isolates associated with toxic shock-like syndrome J Clin Microbiol 29 1991 1562 1567
5. V. Kapur M.W. Majesky L.L. Li R.A. Black J.M. Musser Cleavage of interleukin 1 beta (IL-1 beta) precursor to produce active IL-1 beta by a conserved extracellular cysteine protease from Streptococcus pyogenes Proc Natnl Acad Sci U S A 90 1993 7676 7680
6. V. Kapur S. Topouzis M.W. Majesky L.L. Li M.R. Hamrick R.J. Hamill J.M. Patti J.M. Musser A conserved Streptococcus pyogenes extracellular cysteine protease cleaves human fibronectin and degrades vitronectin Microbial Pathogen 15 1993 327 346
7. B.B. Wolf C.A. Gibson V. Kapur I.M. Hussaini J.M. Musser S.L. Gonias Proteolytically active streptococcal pyrogenic exotoxin B cleaves monocytic cell urokinase receptor and releases an active fragment of the receptor from the cell surface J Biol Chem 269 1994 30682 30687
8. V. Kapur J.T. Maffei R.S. Greer L.L. Li G.J. Adams J.M. Musser Vaccination with streptococcal extracellular cysteine protease (interleukin-1 beta convertase) protects mice against challenge with heterologous group A streptococci Microbial Pathogen 16 1994 443 450
9. K.H. Johnston J.B. Zabriskie Purification and partial characterization of the nephritis strain-associated protein from Streptococcus pyogenes, group A J Exper Med 163 1986 697 712
10. Immunizations, E. Harlow D. Lane Antibodies: A Laboratory Manual 1988 Cold Spring Harbor Laboratory Press Cold Spring Harbor 38 53
11. J. Bailar F. Mosteller Medical Uses of Statistics 2nd ed 1992 NEJM Books Boston 449
12. C.E. Yu J.J. Ferretti Frequency of the erythrogenic toxin B and C genes (SpeB and SpeC) among clinical isolates of group A streptococci Infec Immun 59 1991 211 215
13. A. Vogt S. Batsford B. Rodriguez-Iturbe R. Garcia Cationic antigens in poststreptococcal glomerulonephritis Clin Nephrol 20 1983 271 279
14. S.E. Holm A. Norrby A.M. Bergholm M. Norgren Aspects of pathogenesis of serious group A streptococcal infections in Sweden 1988–1989 J Infect Dis 166 1992 31 37
15. A. Norrby-Teglund K. Pauksens S.E. Holm M. Norgren The reation between low capacity of human sera to inhibit streptococcal mitogens and serious manifestations of disease J Infect Dis 170 1996 585 591
16. G.H. Stollerman Nephritogenic and rheumatogenic group A streptococci J Infect Dis 120 1969 258 263
17. G.A. Andres L. Accinni K.C. Hsu J.B. Zabriskie B.C. Seegal Electron microscopic studies of human glomerulonephritis with ferritin-conjugated antibody. Localization of antigen-antibody complexes in glomerular structures of patients with acute glomerulonephritis J Exper Med 123 1966 399 412
18. K. Lange G. Seligson W. Cronin Evidence for the in situ origin of poststreptococcal glomerulonephritis: Glomerular localization of endostreptosin and the clinical significance of the subsequent antibody response Clin Nephrol 19 1983 3 10
19. G. Seligson K. Lange H.A. Majeed H. Deol W. Cronin R. Bovie Significance of endostreptosin antibody titers in poststreptococcal glomerulonephritis Clin Nephrol 24 1985 69 75
20. N. Yoshizawa S. Oshima I. Sagel J. Shimizu G. Treser Role of a streptococcal antigen in the pathogenesis of acute poststreptococcal glomerulonephritis. Characterization of the antigen and a proposed mechanism for the disease J Immunol 148 1992 3110 3116
21. H. Villarreal Jr V.A. Fischetti I. van de Rijn J.B. Zabriskie The occurrence of a protein in the extracellular products of streptococci isolated from patients with acute glomerulonephritis J Exper Med 149 1979 459 472
22. H. Ohkuni J. Friedman I. van de Rijn V.A. Fischetti T. Poon-King J.B. Zabriskie Immunological studies of post-streptococcal sequelae: Serological studies with an extracellular protein associated with nephritogenic streptococci Clin Exper Immunol 54 1983 185 193
23. S. Mezzano E. Burgos R. Mahabir E. Kemeny J.B. Zabriskie Failure to detect unique reactivity to streptococcal streptokinase in either the sera or renal biopsy specimens of patients with acute poststreptococcal glomerulonephritis Clin Nephrol 38 1992 305 310
24. T.Y. Liu S.D. Elliot Streptococcal proteinase, The Enzymes 3rd ed 1971 Academic Press New York
25. S. Batsford T. Oite H. Takamiya A. Vogt Anionic binding sites in the glomerular basement membrane: Possible role in the pathogenesis of immune complex glomerulonephritis Renal Physiol 3 1980 336 340
26. G.R. Gallo M.E. Lamm Glomerular deposition diseases: Insights into mechanisms Uremia Invest 8 1984 189 192
27. G.R. Gallo T. Caulin-Glaser S.N. Emancipator M.E. Lamm Nephritogenicity and differential distribution of glomerular immune complexes related to immunogen charge Lab Invest 48 1983 353 362
28. G.R. Gallo T. Caulin-Glaser M.E. Lamm Charge of circulating immune complexes as a factor in glomerular basement membrane localization in mice J Clin Invest 67 1981 1305 1313
29. T. Caulin-Glaser G.R. Gallo M.E. Lamm Nondissociating cationic immune complexes can deposit in glomerular basement membrane J Exper Med 158 1983 1561 1572
30. G.R. Gallo T. Caulin-Glaser M.E. Lamm Role of electrostatic charge interactions in glomerular deposition of immune complexes Pathobiol Ann 12 1982 203 211
31. T. Caulin-Glaser S.N. Emancipator G.R. Gallo M.E. Lamm Charge-related deposition of immune complexes in the glomerular basement membrane is independent of Fc effector function Am J Pathol 119 1985 288 293
32. F.J. Dixon M.B.A. Oldstone G. Tionetti Pathogenesis of immune complex glomerulonephritis of New Zealand mice J Exper Med 134 1971 655 713
33. R. Lottenberg L.E. DesJardin H. Wang M.D. Boyle Streptokinase-producing streptococci grown in human plasma acquire unregulated cell-associated plasmin activity J Infect Dis 166 1992 436 440
34. Y. Fujigaki S.R. Batsford D. Bitter-Suermann A. Vogt Complement system promotes transfer of immune complex across glomerular filtration barrier Lab Invest 72 1995 25 33