Effect of food on the bioavailability of omeprazole

International Journal of Pharmaceutical Medicine

Volumn 12, Issue 4, 1998, Pages 199-202

  Pillai, G K ^a   Hassan, M M ^b   Salem, M Sheikh ^b   Najib, N M ^b  

^a AL AHLIYYA AMMAN UNIVERSITY   (Jordan)

^b JORDAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Jordan)

Author keywords

Bioavailability; Food drug interactions; Omeprazole; Pharmacokinetics

Indexed keywords

OMEPRAZOLE;

ADULT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; FOOD DRUG INTERACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; MALE; MEAN RESIDENCE TIME; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

EID: 0031684164     PISSN: 13649027     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Bader JP. Modigliani R, Solule JC, Delichier JC, Morin. An open trial of ome-prazole in short-term treatment of duodenal ulcer. Scantd J Gastroenterol 1986; 21:177-178.
2. Dent J, Klinkenberg-Knol EC, Elm G, Errikson K, Rikner L. Omeprazole in the long-term management of patients with reflex oesophagitis refractory tohistamine H2 receptor antagonists. Scand J Gastroenterol 1989; 24:176.
3. Maton PN. Vinayak R, Frucht H. McArthur KA, Miller LS. Long-term efficacy and safety of omeprazole in patients with Zollinger-Ellison syndrome: a prospective study. Gastroenterol 1989; 97:827-836.
4. Maton PN. Omeprazole: a review. New Engl JMed 1991 ; 324:965-972.
5. Prichard PA, Yeomans ND. Mihaly GW, Jones DB, Buckle PJ. Omeprazole: a study of its inhibition of gastric pH and oral pharmacokinetics after morning or evening dosage. Gastroenterol 1985; 88:64-69.
6. Amantea MA, Narang PK. Improved procedure for quantitation of omeprazole and metabolites using reversed-phase high performance liquid chromatography. J Chromat 1988; 426:216-222.
7. Pillai GK, Salem MS, Najib NM et al. Bioequivalence study of two capsule formulations of omeprazole. Acta Pharm Hungar1996; 66:231-235.
8. Schumacher RC. PKCALC: a basic interactive computer program for statistical and pharmacokinetic analysis. Drug Metab Rev 1986; 17:331-348.
9. Toothaker RD, Welling PG. The effect of food on drug bioavailability. Ann Rev Pharmacol Toxicol 1980; 20:173-199.
10. Welling PG. Interactions affecting drug absorption. Clin Pharmacokin 1984: 9:404-434.
11. Sriwatanakul K, Weintraub M. Understanding food-drug interactions. Comprehensive Ther 1983; 9:6-12.
12. PilbrantA, Cederberg C. Development of an oral formulation of omeprazole. Scand J Gasrroenterol 1985; 20(Suppl 108):113-120.
13. Andersson T, Andren K, Cederberg C, A, Heggelund A, Lundborg P, Rohss K. Bioavailabiltiy of omeprazole as enteric coated (EC) granules in conjunction with food on the first and seventh days of treatment. Drug Invest (1990); 2:184-188.