Evolution of the apolipoprotein E receptor 2 gene by exon loss

Journal of Biochemistry

Volumn 124, Issue 2, 1998, Pages 451-456

  Kim, Hyoun Ju ^a   Kim, Dong Ho ^a   Magoori, Kenta ^a   Saeki, Shigeru ^b   Yamamoto, Tokuo T ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b Osaka Prefecture University   (Japan)

Author keywords

apoE receptor; Exon shuffling; Exon skipping; Pseudo exon; Repetitive sequence

Indexed keywords

APOLIPOPROTEIN E; LIPOPROTEIN RECEPTOR;

ARTICLE; DELETION MUTANT; EVOLUTION; EXON; FRAMESHIFT MUTATION; HUMAN; LIGAND BINDING; MOUSE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PRIMATE; RECEPTOR GENE;

EID: 0031680572     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022134     Document Type: Article

References (28)

1. Gilbert, W. (1978) Why genes in pieces? Nature 271, 501
2. Gilbert, W. (1985) Genes-in-pieces revised. Science 228, 823-824
3. Gilbert, W., de Souza, S.J., and Long, M. (1997) Origin of genes. Proc. Natl. Acad. Sci. USA 94, 7698-7703
4. Südhof, T.C., Goldstein, J.L., Brown, M.S., and Russell, D.W. (1985) The LDL receptor gene: a mosaic of exons shared with different proteins. Science 228, 815-822
5. Kim, D.H., Iijima, H., Goto, K., Sakai, J., Ishii, H., Kim, H.J., Suzuki, H., Kondo, H., Saeki, S., and Yamamoto, T. (1996) Human apolipoprotein E receptor 2. A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain. J. Biol. Chem. 271, 8373-8380
6. Kim, D.H., Magoori, K., Inoue, T.R., Mao, C.C., Kim, H.J., Suzuki, H., Fujita, T., Endo, Y., Saeki, S., and Yamamoto, T.T. (1997) Exon/intron organization, chromosome localization, alternative splicing, and transcription units of the human apolipoprotein E receptor 2 gene. J. Biol. Chem. 272, 8498-8504
7. Takahashi, S., Kawarabayasi, Y., Nakai, T., Sakai, J., and Yamamoto, T. (1992) Rabbit very low density lipoprotein receptor: a low density lipoprotein receptor-like protein with distinct ligand specificity. Proc. Natl. Acad. Sci. USA 89, 9252-9256
8. Sakai, J., Hoshino, A., Takahashi, S., Miura, Y., Ishii, H., Suzuki, H., Kawarabayasi, Y., and Yamamoto, T. (1994) Structure, chromosome location, and expression of the human very low density lipoprotein receptor gene. J. Biol. Chem. 269, 2173-2182
9. Esser, V., Limbird, L.E., Brown, M.S., Goldstein, J.L., and Russell, D.W. (1988) Mutational analysis of ligand binding domain of the low density lipoprotein receptor. J. Biol. Chem. 263, 13282-13290
10. Russell, D.W., Brown, M.S., and Goldstein, J.L. (1989) Different combinations of cysteine-rich repeats mediate binding of low density lipoprotein receptor to two different proteins. J. Biol. Chem. 264, 21682-21688
11. Davis, C.G., Goldstein, J.L., Sudhof, T.C., Anderson, R.G., Russell, D.W., and Brown, M.S. (1987) Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region. Nature 326, 760-765
12. Davis, C.G., Elhammer, A., Russell, D.W., Schneider, W.J., Kornfeld, S., Brown, M.S., and Goldstein, J.L. (1986) Deletion of clustered O-linked carbohydrates does not impair function of low density lipoprotein receptor in transfected fibroblasts. J. Biol. Chem. 261, 2828-2838
13. Chen, W.J., Goldstein, J.L., and Brown, M.S. (1990) NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor. J. Biol. Chem. 265, 3116-3123
14. Brown, M.S. and Goldstein, J.L. (1986) A receptor-mediated pathway for cholesterol homeostasis. Science 232, 34-47
15. Yamamoto, T., Davis, C.G., Brown, M.S., Schneider, W.J., Casey, M.L., Goldstein, J.L., and Russell, D.W. (1984) The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA. Cell 39, 27-38
16. Novak, S., Hiesberger, T., Schneider, W.J., and Nimpf, J. (1996) A new low density lipoprotein receptor homologue with 8 ligand binding repeats in brain of chicken and mouse. J. Biol. Chem. 271, 11732-11736
17. Jaworski, C.J. and Piatigosky, J. (1989) A pseudo-exon in the functional αA-crystallin gene. Nature 337, 752-754
18. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd ed., Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
19. Sanger, F., Nicklen, S., and Coulson, A.R. (1977) DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74, 5463-5467
20. Osuga, J., Inaba, T., Harada, K., Yagyu, H., Shimada, M., Yazaki, Y., Yamada, N., and Ishibashi, S. (1995) Cloning and structural analysis of the mouse apolipoprotein B mRNA editing protein gene. Biochem. Biophys. Res. Commun. 214, 653-662
21. Pearson, W.R. and Lipman, D.J. (1988) Improved tools for biological sequence comparison. Proc. Natl. Acad. Sci. USA 85, 2444-2448
22. Altschul, S.F., Gish, W., Miller, W., Myers, E.W., and Lipman, D.J. (1990) Basic local alignment search tool. J. Mol. Biol. 215, 403-410
23. Kingsley, D.M. and Krieger, M. (1984) Receptor-mediated endocytosis of low density lipoprotein: somatic cell mutants define multiple genes required for expression of surface-receptor activity. Proc. Natl. Acad. Sci. USA 81, 5454-5458
24. Kovanen, P.T., Brown, M.S., Basu, S.K., Bilheimer, D.W., and Goldstein, J.L. (1981) Saturation and suppression of hepatic lipoprotein receptors: a mechanism for the hypercholesterolemia of cholesterol-fed rabbits. Proc. Natl. Acad. Sci. USA 78, 1396-1400
25. Goldstein, J.L., Basu, S.K., and Brown, M.S. (1983) Receptor-mediated endocytosis of low-density lipoprotein in cultured cells. Methods Enzymol. 98, 241-260
26. Barakat, H.A. and St. Clair, R.W. (1985) Characterization of plasma lipoproteins of grain-and cholesterol-fed White Carneau and Show Racer pigeons. J. Lipid Res. 26, 1252-1268
27. Hermier, D., Forgez, P., and Chapman, M.J. (1985) A density gradient study of the lipoprotein and apolipoprotein distribution in the chicken, Gallus domesticus. Biochim. Biophys. Acta 836, 105-118
28. Hodges, D. and Bernstein, S.I. (1994) Genetic and biochemical analysis of alternative RNA splicing. Adv. Genet. 31, 207-281