Left-ventricular expression of interleukin-6 messenger-RNA higher in idiopathic dilated than in ischemic cardiomyopathy

Thoracic and Cardiovascular Surgeon

Volumn 46, Issue 4, 1998, Pages 213-216

  Plenz, G ^a,b   Song, Z F ^a   Reichenberg, S ^a   Tjan, T D T ^b   Robenek, H ^a   Deng, M C ^b  

^a Inst for Arteriosclerosis Research

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Explant cardiac tissue; Idiopathic dilated cardiomyopathy; Interleukin 6 mRNA; Ischemic cardiomyopathy; Northern analysis

Indexed keywords

GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INTERLEUKIN 6; MESSENGER RNA;

ADULT; ARTICLE; CLINICAL ARTICLE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HEART LEFT VENTRICLE; HUMAN; HUMAN TISSUE; ISCHEMIC HEART DISEASE; MALE; PRIORITY JOURNAL;

EID: 0031679963     PISSN: 01716425     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-1010227     Document Type: Article

References (27)

1. Munger MA, Johnson B, Amber IJ, Callahan KS, Gilbert EM. Circulating concentrations of proinflammatory cytokines in mild or moderate heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. Am J Cardiol. 1996;77:723-7.
2. Torre-Amione C, Kapadia S, Benedict C, Oral C, Young JB, Mann DL. Proinflammatory cytokine levels in patients with depressed left-ventricular ejection fraction: a report from the studies of left-ventricular dysfunction (SOLVD). J Am Coll Cardiol. 1996;27:1201-6.
3. Deng MC, Erren M, Lütgen A, et al. Interleukin-6 correlates with hemodynamic impairment during dobutamine administration in chronic heart failure. Int J Cardiol. 1996;57:129-34.
4. Finkel MS, Oddis CV, Jacob TD, Watkins SC, Hattler BG, Simmons RL. Negative inotropic effects of cytokines on the heart mediated by nitric oxide. Science. 1992;257:387-9.
5. Finkel MS, Hoffman RA, Shen L, Oddis CV, Simmons RL, Hattler BG. Interleukin-6 (IL6) as a mediator of stunned myocardium. Am J Cardiol. 1993;71:1231-3.
6. Gulick T, Chung MK, Pieper SJ, Schreiner GF, Lange LG. Immune cytokine inhibition of beta-adrenergic agonist stimulated cyclic AMP generation in cardiac myocytes. Biochem Biophys Res Commun. 1988;150:1-9.
7. Mann DL, Young JB. Basic mechanism in congestive heart failure: recognizing the role of proinflammatory cytokines. Chest. 1994;105:897-904.
8. Oral H, Dorn GW, Mann DL Sphingosine mediates the immediate negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian cardiac myocyte. J Biol Chem. 1997;272:4836-42.
9. Neumann F-J, Ott I, Gawaz M, Richardt G, Holzapfel H, Jochum M, Schömig A. Cardiac release of cytokines and inflammatory responses in acute myocardial infarction. Circulation. 1995;92:748-55.
10. Biasucci LM, Vitelli A, Liuzzi G, et al. Elevated levels of interleukin-6 in unstable angina. Circulation. 1996;94:874-7.
11. Wan S, DeSmet JM, Barvais L. Goldstein M, Vincent JL, LeClerc JL. Myocardium is a major source of proinflammatory cytokines in patients undergoing cardiopulmonary bypass. J Thorac Cardiovasc Surg. 1996;112:806-11.
12. Cunningham DA, Dunn MJ, Yacoub MH, Rose ML. Local production of cytokines in the human cardiac allograft: a sequential study. Transplantation. 1994;57:1333-7.
13. Lagoo AS, George JF, Naftel DC, et al. Semiquantitative measurements of cytokine messenger RNA in endomyocardium and peripheral blood mononuclear cells from human heart transplant recipients. J Heart Lung Transplant. 1996;15:206-17.
14. Deng MC, Breithardt G, Scheld HH. Interdisciplinary Heart Failure and Transplant Program Münster: A 5-year experience. Int J Cardiol. 1995;50:7-17.
15. Chirgwin JM, Przybyla AE, McDonald RJ, Rutter WJ. Isolation of biological active ribonucleic acid from sources enriched in ribonuclease. Biochemistry. 1979;18:5294-9.
16. Loeffler JA, Plenz G, Siegert R, Weerda H, Mueller PK. Experimental tissue expansion induces changes in expression of procollagen 1 and III messenger RNA. Eur Arch Otorhinolaryngol. 1995;252: 475-7.
17. Plenz G, Koenig C, Severs NJ, Robenek H. Smooth-muscle cells express granulocyte-macrophage colony stimulating factor (GM-CSF) in the undiseased and atherosclerotic human coronary artery. Arterioscler Throm Vasc Biol. 1997;17:2489-99.
18. Zhao XM, Yeoh TK, Hiebert M, Frist WH, Miller GG. The expression of acidic fibroblast growth factor (heparin-binding growth factor-1) and cytokine genes in human cardiac allografts and T cells. Transplantation. 1993;56:1177-82.
19. Torre-Amione G, Kapadia S, Lee J, Durand JB, Bies RD, Young JB, Mann DL. Tumor-necrosis factor-α and tumor-necrosis factor receptors in the failing human heart. Circulation. 1996;93:704-11.
20. Lange LG, Schreiner GF. Immune mechanisms of cardiac disease. N Engl J Med. 1994;330:1129-35.
21. Chrousos GP. The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. N Engl J Med. 1995;332:1351-62.
22. Yamauchi-Takihara K, Yoshiji I, Ogata A, Yoshizaki K, Azuma J, Kishimoto T. Hypoxic stress induces cardiac myocyte-derived interleukin-6. Circulation. 1995;91:1520-4.
23. Taga T, Kishimoto T. Gp130 and the interleukin-6 family of cytokines. Ann Rev Immunol. 1997;15:797-819.
24. Hirota H, Yoshida K, Kishimoto T, Taga T. Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice. Proc Natl Acad Sci USA. 1995;92:4862-6.
25. DeBelder AJ, Radomski MW, Why HJF, et al. Nitric oxide synthase activities in human myocardium. Lancet. 1993;341:84-5.
26. DeBelder AJ, Radomski MW, Why HJF, Richardson PJ, Martin JF. Myocardial calcium-independent nitric oxide synthase activity is present in dilated cardiomyopathy, myocarditis, and postpartum cardiomyopathy but not in ischemic or valvular heart disease. Br Heart J. 1995;74:426-30.
27. Kukielka GL, Smith CW, Manning AM, Youke KA, Michael LH, Entman ML. Induction of interleukin-6 synthesis in the myocardium. Potential role in postreperfusion inflammatory injury. Circulation. 1995;92:1866-75.