Mechanism and specificity of lanthanide series cation transport by ionophores A23187, 4-BrA23187, and ionomycin

Biophysical Journal

Volumn 75, Issue 3, 1998, Pages 1244-1254

  Wang, Exing ^a   Taylor, Richard W ^b   Pfeiffer, Douglas R ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROMOCALCIMYCIN; CALCIMYCIN; IONOMYCIN; LANTHANIDE; PHOSPHATIDYLCHOLINE; QUIN 2;

ARTICLE; CATION TRANSPORT; CELL MEMBRANE TRANSPORT; CHANNEL GATING; CHEMICAL STRUCTURE; CONCENTRATION RESPONSE; MEMBRANE POTENTIAL; PHOSPHOLIPID VESICLE; STOICHIOMETRY; STRUCTURE ACTIVITY RELATION;

EID: 0031679212     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(98)74044-5     Document Type: Article

References (44)

1. Albin, M., B. M. Cader, and Horrocks, Jr. 1984. Lanthanide complexes of Ionophore. 2. Spectroscopic characterization of lanthanide (III) ion binding to lasalocid A and A23187. Inorg. Chem. 23:3045-3050.
2. Amellel, M., and Y. Landry. 1983. Lanthanides are transported by ionophore A23187 and mimic calcium in the histamine release process. Br. J. Pharmacol. 80:365-370.
3. Bartlett, G. R. 1959. Phosphorous assay in column chromatography. J. Biol. Chem. 234:466-468.
4. Blau, L., R. B. Stern, and R. Bittman. 1984. The stoichiometry of A23187- and X537A-mediated calcium ion transport across lipid bilayers. Biochim. Biophys. Acta. 778:219-223.
5. Blau, L., and G. Weissmann. 1988. Transmembrane calcium movements mediated by ionomycin and phosphatidate in liposomes with fura 2 entrapped. Biochemistry. 27:5661-5666.
6. Chapman, C. J., W. L. Erdahl, R. W. Taylor, and D. R. Pfeiffer. 1990a. Factors affecting solute entrapment in POPC vesicles prepared by the freeze-thaw extrusion method. Chem. Phys. Lipids. 55:73-83.
7. Chapman, C. J., W. L. Erdahl, R. W. Taylor, and D. R. Pfeiffer. 1991. Effect of solute concentration on the entrapment of solutes in phospholipid vesicles prepared by freeze-thaw extrusion. Chem. Phys. Lipids. 60:201-208.
8. Chapman, C. J., A. K. Puri, R. W. Taylor, and D. R. Pfeiffer. 1987. Equilibria between ionophore A23187 and divalent cations: the stability of 1:1 complexes in solutions of 80% methanol/water. Biochemistry. 26:5009-5018.
9. Chapman, C. J., A. K. Puri, R. W. Taylor, and D. R. Pfeiffer. 1990b. General features in the stoichiometry and stability of ionophore A23187-cation complexes in homogenous solution. Arch. Biochem. Biophys. 281:44-57.
10. 2+ transport specificity by the 4-bromo derivative. Biochemistry. 20:6865-6872.
11. 2+ transport properties of ionophores A23187, ionomycin, and 4-BrA23187 in a well defined system. Biophys. J. 66:1678-1693.
12. 2+ transport catalyzed by ionophores A23187, 4-BrA23187, and ionomycin suggest problems with common applications of these compounds in biological systems. Biophys. J. 69:2350-2363.
13. 2+. Biochemistry. 35:13817-13825.
14. Fasolato, C., and T. Pozzan. 1989. Effect of membrane potential on divalent cation transport catalyzed by the "electroneutral" ionophores A23187 and ionomycin. J. Biol. Chem. 264:19630-19636.
15. Fry, D. W., J. C. White, and D. Goldman. 1978. Rapid separation of low molecular weight solutes from liposomes without dilution. Anal. Biochem. 90:809-815.
16. 3+ across lipid bilayers in the presence of two chemically distinct ionophores. J. Am. Chem. Soc. 106:1472-1476.
17. 1H NMR spectroscopy. FEBS Lett. 58:194-196.
18. 1H-NMR spectroscopy. Sci. Rep. 2:921-928.
19. 1H NMR theoretical study. Biophys. Chem. 8:341-355.
20. Jones, E. B. J., D. J. Nelson, and M. M. Turnbull. 1992. Enhancement and quenching of fluorescence of Quin-2 by metal ions. J. Inorg. Biochem. 45:85-92.
21. Kamo, N., M. Muratsugu, R. Hongoh, and Y. Kobatake. 1979. Membrane potential of mitochondria measured with an electrode sensitive to tetraphenylphosphonium and relationship between proton electrochemical potential and phosphorylation potential in steady state. J. Membr. Biol. 49:105-121.
22. Kolber, M. A., and D. H. Haynes. 1981. Fluorescence study of the divalent cation transport mechanism of ionophore A23187 in phospholipid membranes. Biophys. J. 36:369-391.
23. 3+ to bilayer membranes: measurement of the adsorption enthalpy and binding constant with titration calorimetry. Biochim. Biophys. Acta. 1189:89-95.
24. Lyle, S. J., and M. Rahman. 1963. Complexometric titration of yttrium and the lanthanons. Talanta. 10:1177-1182.
25. Montal, M. 1970. Experimental membranes and mechanisms of bioenergy transduction. Annu. Rev. Bioeng. 5:119-175.
26. Perrin, D. D., and I. G. Sayce. 1967. Computer calculation of equilibrium concentrations in mixtures of metal ions and complexing species. Talanta. 14:833-842.
27. Pfeiffer, D. R., S. M. Hutson, R. F. Kaufman, and H. A. Lardy. 1976. Some effects of ionophore A23187 on energy utilization and the distribution of cations and anions in mitochondria. Biochemistry. 15:2690-2697.
28. + transport in mitochondria mediated by A23187. Biochemistry. 15:935-943.
29. Pfeiffer, D. R., R. W. Taylor, and H. A. Lardy. 1978. Ionophore A23187: cation binding and transport properties. Ann. N.Y. Acad. Sci. 307: 402-423.
30. Puskin, J. S., and T. E. Gunter. 1975. Electron paramagnetic resonance of copper ion and magnesium ion complexes with A23187. Biochemistry. 14:187-191.
31. Shastri, B. P., M. B. Sankaram, and K. R. K. Easwaran. 1987. Carboxylic ionophore (lasalocid A and A23187) mediated lanthanide ion transport across phospholipid vesicles. Biochemistry. 26:4925-4930.
32. Smith, G. D., and W. L. Duax. 1976. Crystal and molecular structure of the calcium complex of A23187. J. Am. Chem. Soc. 98:1578-1580.
33. Stiles, M. K., M. E. Craig, S. L. N. Gunnell, D. R. Pfeiffer, and R. W. Taylor. 1991. The formation constants of ionomycin with divalent cations in 80% methanol-water. J. Biol. Chem. 266:8336-8342.
34. Taylor, R. W., R. F. Kaufman, and D. R. Pfeiffer. 1982. Cation complexation and transport by carboxylic acid ionophores. In Polyether Antibiotics: Naturally Occurring Acid Ionophores. J. W. Westley, editor. Marcel Dekker, New York. 103-184.
35. Thomas, T. P., E. Wang, D. R. Pfeiffer, and R. W. Taylor. 1997. Evidence against formation of A23187 dimers and oligomers in solution: photoinduced degradation of ionophore A23187. Arch. Biochem. Biophys. 342:351-361.
36. Tissier, C., J. Juillard, D. W. Boyd, and A. M. Albrecht-Gary. 1985. Mode of action of calcimycin (A 23187). II. A study of its interactions with alkali and alkali-earth cations in methanol-water mixtures. J. Chim. Phys. 82:899-906.
37. Tissier, M., A. Ouahabi, G. Jeminet, and J. Juillard. 1993. Mode of action of calcimycin (A23187). VI. Complexation of transition and heavy metal divalent cations in methanol. J. Chim. Phys. 90:595-608.
38. Tocanne, J.-F., and J. Teissié. 1990. Ionization of phospholipids and phospholipid-supported interfacial lateral diffusion of protons in membrane model systems. Biochim. Biophys. Acta. 1031:111-142.
39. Toepilitz, B. K., A. I. Cohen, P. T. Funke, W. L. Parker, and T. Z. Gougoutas. 1979. Structure of ionomycin - a novel diacidic polyether antibiotic having high affinity for calcium ions. J. Am. Chem. Soc. 101:3344-3353.
40. Vogel, A. I. 1961. Determination of copper using fast sulphon black F indicator. In Quantitative Inorganic Analysis, 3rd ed., Wiley, New York. 415-467.
41. 2+ ionophores. Biophys. J. 70:A366.
42. Westley, J. W. 1983. Chemical transformation of polyether antibiotics. In Polyether Antibiotics, Naturally Occurring Acid Ionophores. J. W. Westley, editor. Marcel Dekker, New York. 51-86.
43. Wrigglesworth, J. M., C. E. Cooper, M. A. Sharpe, and P. Nicholls. 1990. The proteoliposomal steady state: effect of size, capacitance and membrane permeability on cytochrome-oxidase-induced ion gradients. Biochem. J. 270:109-118.
44. Yuchi, A. A., M. Tanaka, T. Hirai, T. Yasui, H. Wada, and G. Nakagawa. 1993. Complexation equilibria and fluorescent properties of chelating reagents derived from ethylene glycol bis(2-aminoethyl ether)-N,N,N′,N′-tetraacetic Acid. Bull. Chem. Soc. Jpn. 66:3377-3381.