Transcriptional activation and redox regulation of the tumor necrosis factor-α promoter in human T cells: Role of the CRE/κ3 promoter region

Journal of Interferon and Cytokine Research

Volumn 18, Issue 11, 1998, Pages 999-1007

  Liu, Beiqing ^a   Whisler, Ronald L ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; HYDROGEN PEROXIDE; PHORBOL 13 ACETATE 12 MYRISTATE; PHYTOHEMAGGLUTININ; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOREGULATION; LEUKEMIA CELL LINE; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; T LYMPHOCYTE; TRANSCRIPTION INITIATION;

EID: 0031678863     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.1998.18.999     Document Type: Article

References (54)

1. SUNG, S.-S.J., BJORNDAHL, J.M., WANG, C.Y., KAO, H.T., and FU, S.M. (1988). Production of tumor necrosis factor/cachectin by human T cell lines and peripheral T lymphocytes stimulated by phorbol myristate acetate and anti-CD3 antibody. J. Exp. Med. 167, 937-953.
2. RHOADES, K.L., GOLUB, S.H., and ECONOMOU, J.S. (1992). The regulation of human tumor necrosis factor α promoter region in macrophage, T cell, and B cell lines. J. Biol. Chem. 267, 22101-22107.
3. HIGUCHI, M., NAGASAWA, K., HORIUCHI, T., OIKE, P., ITO, Y., YASUKAWA, M., and NIHO, Y. (1997). Membrane tumor necrosis factor-α (TNF-) expressed on HTLV-I-infected T cells mediates a costimulatory signal for B cell activation - characterization of membrane TNF-α. Clin. Immunol. Immunopathol. 82, 133-140.
4. LOWENTHAL, J.W., BALLARD, D.W., BOGERD, H., BOHNLEIN, E., and GREENE, W.C. (1989). Tumor necrosis factor-α activation of the IL-2 receptor-α gene involves the induction of κB-specific DNA binding proteins. J. Immunol. 142, 3121-3128.
5. PIMENTEL-MUIÑOS, F.X., MAZANA, J., and FRESNO, M. (1994). Regulation of interleukin-2 receptor α chain expression and nuclear factor kappaB activation by protein kinase C in T lymphocytes. Autocrine role of tumor necrosis factor α. J. Biol. Chem. 269, 24424-24429.
6. PIMENTEL-MUINĨOS, F.X., MUÑOZ-FERNÁNDEZ, M.A., and FRESNO, M. (1994). Control of T lymphocyte activation and IL-2 receptor expression by endogenously secreted lymphokines. J. Immunol. 152, 5714-5722.
7. KINKHABWALA, M., SEHAJPAL, P., SKOLNIK, E., SMITH, D., SHARMA, V.K., VLASSARA, H., CERAMI, A., and SUTHANTHIRAN, M. (1990). A novel addition to the T cell repertory. Cell surface expression of tumor necrosis factor/cachectin by activated normal human T cells. J. Exp. Med. 171, 941-946.
8. SANTIS, A.G., CAMPANERO, M.R., ALONSO, J.L., TUGORES, A., ALONSO, M.A., PIVEL, J.P., and SANCHEZ-MADRID, F. (1992). Tumor necrosis factor-α production induced in T lymphocytes through the AIM/CD69 activation pathway. Eur. J. Immunol. 22, 1253-1259.
9. STANDIFORD, T.J., LINDSTEN, T., THOMPSON, C.B., STRIETER, R.M., and KUNKEL, S.L. (1992). Interleukin-4 differentially regulates tumor necrosis factor-α gene expression by human T lymphocytes and monocytes. Pathobiology 60, 100-107.
10. + T cell clones provides a costimulatory signal for human B cell activation. J. Exp. Med. 177, 1575-1585.
11. POPE, R.M., LEUTZ, A., and NESS, S.A. (1994). C/EBPβ regulation of the tumor necrosis factor α gene. J. Clin. Invest. 94, 1449-1455.
12. CRABTREE, G.R., and CLIPSTONE, N.A. (1994). Signal transmission between the plasma membrane and nucleus of T lymphocytes. Annu. Rev. Biochem. 63, 1045-1083.
13. GLICKSTEIN, L., MACPHAIL, S., and STUTMAN, O. (1996). Uncoupling IL-2 production from apoptosis and TNF production by changing the signal through the TCR. J. Immunol. 156, 2062-2067.
14. BEUTLER, B., MILSARK, I.W., and CERAMI, A.C. (1985). Passive immunization against cachetin/tumor necrosis factor protects mice from lethal effect of endotoxin. Science 229, 869-871.
15. IMAGAWA, D.K., MILLIS, J.M., and OLTHOFF, K.M. (1990). The role of tumor necrosis factor in allograft rejection. I. Evidence that elevated levels of tumor necrosis factor-alpha predict rejection following orthotopic liver transplantation. Transplantation 50, 219-225.
16. COLLETTI, L.M. REMICK, D.G., BURTCH, G.D., KUNKEL, S.L., STRIETER, R.M., and CAMPBELL, D.A. (1990). Role of tumor necrosis factor-α in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat. J. Clin. Invest. 85, 1936-1943.
17. HALLIWELL, B., and GUTTERIDGE, J.M.C. (1990). Role of Free Radicals and Catalytic Ions in Human Disease: An Overview. San Diego, CA: Academic Press, pp. 1-85.
18. FIERS, W. (1991). Tumor necrosis factor. Characterization at the molecular, cellular and in vitro level. FEBS Lett. 285, 199-212.
19. BEMELMANS, M.H.A., VAN TITS, L.J.H., and BUURMAN, W.A. (1996). Tumor necrosis factor: function, release and clearance. Crit. Rev. Immunol. 16, 1-11.
20. MACCHIA, D., ALMERIGOGNA, F., PARRONCHI, P., RAVINA, A., MAGGI, E., and ROMAGNANI, S. (1993). Membrane tumour necrosis factor-α is involved in the polyclonal B-cell activation induced by HIV-infected human T cells. Nature 363, 464-466.
21. KOVACS, B., VASSILOPOULOS, D., VOGELGESANG, S.A., and TSOKOS, G.C. (1996). Defective CD3-mediated cell death in activated T cells from patients with systemic lupus erythematosus: role of decreased intracellular TNF-α. Clin. Immunol. Immunopathol. 81, 293-302.
22. + T-cell clones. Blood 89, 1440-1445.
23. SCHRECK, R., RIEBER, P., and BAEUERLE, P.A. (1991). Reactive oxygen intermediates as apparently widely used messengers in the activation of NFκB transcription factor and HIV-l. EMBO J. 10, 2247-2258.
24. fyn tyrosine kinases in human lymphocytes. Blood 82, 1212-1220.
25. SECRIST, J.P., BURNS, L.A., KARNITZ, L., KORETZKY, G.A., and ABRAHAM, R.T. (1993). Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate on T-cell activation events. J. Biol. Chem. 268, 5886-5893.
26. 2 and antioxidants have opposite effects on activation of NF-kappaB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO J. 12, 2005-2015.
27. 2-induced T cell signal transduction. J. Biol. Chem. 269, 20718-20726.
28. WHISLER, R.L., NEWHOUSE, Y.G., BEIQING, L., KARANFILOV, B.K., GOYETTE, M.A., and HACKSHAW, K.V. (1994). Regulation of protein kinase enzymatic activity in Jurkat T cells during oxidative stress uncoupled from protein tyrosine kinases: role of oxidative changes in protein kinase activation requirements and generation of second messengers. Lymphokine Cytokine Res. 13, 399-410.
29. BAEUERLE, P.A., and HENKEL, T. (1994). Function and activation of NF-kappaB in the immune system. Annu. Rev. Immunol. 12, 141-179.
30. FLESCHER, E., LEDBETTER, J.A., SCHIEVEN, G.L., VELAROCH, N., FOSSUM, D., DANG, H., OGAWA, N., and TALAL, N. (1994). Longitudinal exposure of human T lymphocytes to weak oxidative stress suppresses transmembrane and nuclear signal transduction. J. Immunol. 153, 4880-4889.
31. SCHULZE-OSTHOFF, K., LOS, M., and BAEUERLE, P.A. (1995). Redox signalling by transcription factors NF-kappaB and AP-1 in lymphocytes. Biochem. Pharmacol. 50, 735-741.
32. WHISLER, R.L., GOYETTE, M.A., GRANTS, I.S., and NEWHOUSE, Y.G. (1995). Sublethal levels of oxidant stress stimulate multiple serine/threonine kinases and suppress protein phosphatases in Jurkat T cells. Arch. Biochem. Biophys. 319, 23-35.
33. LIU, B.Q., CHEN, M., and WHISLER, R.L. (1996). Sublethal levels of oxidative stress stimulate transcriptional activation of c-jun and suppress IL-2 promoter activation in Jurkat T cells. J. Immunol. 157, 160-169.
34. LAHDENPOHJA, N., SAVINAINEN, K., and HURME, M. (1998). Pre-exposure to oxidative stress decreases the nuclear factor-κB-dependent transcription in T lymphocytes. J. Immunol. 160, 1354-1358.
35. 2 pool generated by human neutrophils. J. Biol. Chem. 259, 399-405.
36. EL-HAG, A., LIPSKY, P.E., BENNETT, M., and CLARK, R.A. (1986). Immunomodulation by neutrophil myeloperoxidase and hydrogen peroxide: differential susceptibility of human lymphocyte functions. J. Immunol. 136, 3420-3426.
37. GOLDFELD, A.E., DOYLE, D., and MANIATIS, T. (1990). Human tumor necrosis factor α gene regulation by virus and lipopolysaccharide. Proc. Natl. Acad. Sci. USA 87, 9769-9773.
38. WYSOCKI, L.J., and SATO, V.L. (1978). "Panning" for lymphocytes: a method for cell selection. Proc. Natl. Acad. Sci. USA 75, 2844-2848.
39. GRANELLI-PIPERNO, A., KEANE, M., and STEINMAN, R.M. (1989). Growth factor production and requirements during the proliferative response of human T lymphocytes to anti-CD3 monoclonal antibody. J. Immunol. 142, 4138-4143.
40. WHISLER, R.L., LIU, B.Q., and CHEN, M. (1996). Age-related decreases in IL-2 production by human T cells are associated with impaired activation of nuclear transcriptional factors AP-1 and NF-AT. Cell. Immunol. 169, 185-195.
41. RHOADES, K.L., CAI, S., GOLUB, S.H., and ECONOMOU, J.S. (1995). Granulocyte-macrophage colony-stimulating factor and interleukin-4 differentially regulate the human tumor necrosis factor-α promoter region. Cell. Immunol. 161, 125-131.
42. YAMAUCHI, A., and BLOOM, E.T. (1993). Requirement of thiol compounds as reducing agents for IL-2-mediated induction of LAK activity and proliferation of human NK cells. J. Immunol. 151, 5535-5544.
43. YIM, C.-Y., HIBBS, J.B., Jr., McGREGOR, J.R., GALINSKY, R.E., and SAMLOWSKI, W.E. (1994). Use of N-acetyl cysteine to increase intracellular glutathione during the induction of antitumor responses by IL-2. J. Immunol. 152, 5796-5805.
44. TSAI, E.Y., JAIN, J., PESAVENTO, P.A., RAO, A., and GOLDFELD, A.E. (1996). Tumor necrosis factor alpha gene regulation in activated T cells involves ATF-2/Jun and NFATp. Mol. Cell. Biol. 16, 459-467.
45. O'KEEFE, S.J., TAMURA, J., KINCAID, R.L., TOCCI, M.J., and O'NEILL, E.A. (1992). FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin. Nature 357, 692-694.
46. McCAFFREY, P.C., LUO, C., KERPPOLA, T.K., JAIN, J., BADALIAN, T.M., HO, A.M., BURGEON, E., LANE, W.S., LAMBERT, J.N., CURRAN, T., VERDINE, G.L., RAO, A., and HOGAN, P.G. (1993). Isolation of the cyclosporin-sensitive T cell transcription factor NFATp. Science 262, 750-754.
47. GOLDFELD, A.E., McCAFFREY, P.G., STROMINGER, J.L., and RAO, A. (1993). Identification of a novel cyclosporin-sensitive element in the human tumor necrosis factor α gene promoter. J. Exp. Med. 178, 1365-1379.
48. LAZDINS, J.K., GRELL, M., WALKER, M.R., WOODS-COOK, K., SCHEURICH, P., and PFIZENMAIER, K. (1997). Membrane tumor necrosis factor (TNF) induced cooperative signaling of TNFR60 and TNFR80 favors induction of cell death rather than virus production in HIV-infected T cells. J. Exp. Med. 185, 81-90.
49. PAHLAVANI, M.A., and RICHARDSON, A. (1996). The effect of age on the expression of interleukin-2. Mech. Ageing Dev. 89, 125-154.
50. FAGIOLO, U., COSSARIZZA, A., SCALA, E., FANALES-BELASIO, E., ORTOLANI, C., COZZI, E., MONTI, D., FRANCESCHI, C., and PAGANELLI, R. (1993). Increased cytokine production in mononuclear cells of healthy elderly people. Eur. J. Immunol. 23, 2375-2378.
51. HAN, D., HOSOKAWA, T., AOIKE, A., and KAWAI, K. (1995). Age-related enhancement of tumor necrosis factor (TNF) production in mice. Mech. Ageing Dev. 84, 39-54.
52. BORN, J., UTHGENANNT, D., DODT, C., NUNNINGHOFF, D., RINGVOLT, E., WAGNER, T., and FEHM, H.-L. (1995). Cytokine production and lymphocyte subpopulations in aged humans. An assessment during nocturnal sleep. Mech. Ageing Dev. 84, 113-126.
53. SEGAL, R., DAYAN, M., GLOBERSON, A., HABUT, B., SHEARER, G.M., and MOZES, E. (1997). Effect of aging on cytokine production in normal and experimental systemic lupus erythematosus afflicted mice. Mech. Ageing Dev. 96, 47-58.
54. PINNER, R.W., TEUTSCH, S.M., SIMONSEN, L., KLUG, L.A., GRABER, J.M., CLARKE, M.J., and BERKELMAN, R.L. (1996). Trends in infectious diseases mortality in the United States. JAMA 275, 189-193.