Murine GBP-2: A new IFN-y-induced member of the GBP family of GTPases isolated from macrophages

Journal of Interferon and Cytokine Research

Volumn 18, Issue 11, 1998, Pages 977-985

  Vestal, Deborah J ^a,b   Buss, Janice E ^c   McKercher, Scott R ^a   Jenkins, Nancy A ^d   Copeland, Neal G ^d   Kelner, Gregory S ^e   Asundi, Vinod K ^f   Maki, Richard A ^a,e  

^a BURNHAM INSTITUTE   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c IOWA STATE UNIVERSITY   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

^e NEUROCRINE BIOSCIENCES INC   (United States)

^f WEIS CENTER FOR RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; GAMMA INTERFERON; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; INTERFERON; MEVALONIC ACID; TRITIUM;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; GENE EXPRESSION; MACROPHAGE; MOLECULAR CLONING; MOUSE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ANIMALIA; MURINAE; TRITIUM;

EID: 0031677602     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.1998.18.977     Document Type: Article

References (57)

1. AUGER, J., and ROSS, J.A. (1992). The biology of the macrophages. In: The Macrophage. C.E. Lewis and J.O.D. McGee (eds.) New York: Oxford University Press, pp. 1-74.
2. KNOP, J. (1990). Immunologic effects of interferon. J. Invest. Dermatol. 95, 72S-75S.
3. WILLIAMS, J.G., JURKOVICH, G.J., and MAIER, R.V. (1993). Interferon-gamma: a key immunoregulatory lymphokine. J. Surg. Res. 54, 79-93.
4. FARRAR, M.A., and SCHREIBER, R.D. (1993). The molecular cell biology of interferon-gamma and its receptor. Annu. Rev. Immunol. 11, 571-611.
5. YOUNG, H.A., and HARDY, K.J. (1995). Role of interferon-gamma in immune cell regulation. J. Leukocyte Biol. 58, 373-381.
6. ADAMS, D.O., and HAMILTON, T.A. (1992). Molecular basis of macrophage activation: diversity and its origin. In: The Macrophage. C.E. Lewis and J.O.D. McGee (eds.) New York: Oxford University Press, pp. 75-114.
7. LEW, D.J., DECKER, T., STREHLOW, I., and DARNELL, J.E. (1991). Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons. Mol. Cell. Biol. 11, 182-191.
8. LEW, D.J., DECKER, T., and DARNELL, J.E., JR. (1989). Alpha interferon and gamma interferon stimulate transcription as a single gene through different signal transduction pathways. Mol. Cell. Biol. 9, 5404-5411.
9. MIRKOVITCH, J., DECKER, T., and DARNELL, J.E., JR. (1992). Interferon induction of gene transcription analyzed by in vivo footprinting. Mol. Cell. Biol. 12, 1-9.
10. DECKER, T., LEW, D.J., and DARNELL, J.E., JR. (1991). Two distinct alpha-interferon-dependent signal transduction pathways may contribute to activation of transcription of the guanylate-binding protein gene. Mol. Cell. Biol. 11, 5147-5153.
11. DECKER, T., LEW, D.J., CHENG, Y.S., LEVY, D.E., and DARNELL, J.E., JR. (1989). Interactions of alpha- and gamma-interferon in the transcriptional regulation of the gene encoding a guanylate-binding protein. EMBO J. 8, 2009-2014.
12. NICOLET, C.M., and PAULNOCK, D.M. (1994). Promoter analysis of an interferon-inducible gene associated with macrophage activation. J. Immunol. 152, 153-162.
13. BRIKEN, V., RUFFNER, H., SCHULTZ, U., SCHWARZ, A., REIS, L.F., STREHLOW, I., DECKER, T., and STAEHELI, P. (1995). Interferon regulatory factor 1 is required for mouse Gbp gene activation by gamma interferon. Mol. Cell. Biol. 15, 975-982.
14. DARNELL, J.E., JR., KERR, I.M., and STARK, G.R. (1994). JakStat pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264, 1415-1421.
15. SCHINDLER, C. (1995). Cytokine signal transduction. Receptor 5, 51-62.
16. IHLE, J.N. (1996). Stats: signal transducers and activators of transcription. Cell 84, 331-334.
17. CHENG, Y.S., PATTERSON, C.E., and STAEHELI, P. (1991). Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP. Mol. Cell. Biol. 11, 4717-4725.
18. STAEHELI, P., COLONNO, R.J., and CHENG, Y.-S.E. (1983). Different mRNAs induced by interferon in cells from inbred mouse strains A/J and A2G. J. Virol. 47, 563-567.
19. WYNN, T.A., NICOLET, C.M., and PAULNOCK, D.M. (1991). Identification and characterization of a new gene family during macrophage activation. J. Immunol. 147, 4384-4392.
20. STAEHELI, P., PROCHAZKA, M., STEIGMEIER, P.A., and HALLER, O. (1984). Genetic control of interferon action: mouse strain distribution and.inheritance of an induced protein with guanylate-binding property. Virology 137, 135-142.
21. CHENG, Y.E., COLONNO, R.J., and YIN FAY, H. (1983). Interferon induction of fibroblast proteins with guanylate binding activity. J. Biol. Chem. 258, 7746-7750.
22. CHENG, Y.-S.E., BECKER-MANLEY, M.F., CHOW, T.P., and HORAN, D.C. (1985). Affinity purification of an interferon-induced human guanylate-binding protein and its characterization. J. Biol. Chem. 260, 15834-15839.
23. SCHWEMMLE, M., KASPERS, B., IRION, A., STAEHELI, P., and SCHULTZ, U. (1996). Chicken guanylate-binding protein. Conservation of GTPase activity and induction by cytokines. J. Biol. Chem. 271, 10304-10308.
24. SCHWEMMLE, M., and STAEHELI, P. (1994). The interferon-induced 67-kDa guanylate-binding protein (hGBP1) is a GTPase that converts GTP to GMP. J. Biol. Chem. 269, 11299-11305.
25. NEUN, R., RICHTER, M.F., STAEHELI, P., and SCHWEMMLE, M. (1996). GTPase properties of the interferon-induced human guanylate-binding protein 2. FEBS Lett. 390, 69-72.
26. DEVER, T.E., GLYNIAS, M.J., and MERRICK, W.C. (1987). GTP-binding domain: three consensus sequence elements with distinct spacing. Proc. Natl. Acad. Sci. USA 84, 1814-1818.
27. DEVER, T.E., and MERRICK, W.C. (1989). The GTP-binding domain revisited. In: The Guanine-Nucleolide Binding Proteins. Volume Nato ASI series. L. Bosch, B. Kraal, and A. Parmeggiani (eds.) New York: Plenum Publishing Corp., pp. 35-48.
28. MCCORMICK, F., CLARK, B.F.C., LACOUR, T.F.M., KJELDGAARD, M., NORSKOV-LAURITSEN, L., and NYBORG, J. (1985). A model for the tertiary structure of p21, the production of the ras oncogene. Science 230, 78-82.
29. MALTESE, W.A. (1990). Posttranslational modification of proteins by isoprenoids in mammalian cells. FASEB J. 4, 3319-3328.
30. SINENSKY, M., and LUTZ, R.J. (1992). The prenylation of proteins. BioEssays 14, 331-340.
31. CASEY. P.J., and SEABRA, M.C. (1996). Protein prenyltransferases. J. Biol. Chem. 271, 5289-5292.
32. NANTAIS, D.E., SCHWEMMLE, M., STICKNEY, J.T., VESTAL, D.J., and BUSS, J.E. (1996). Prenylation of an interferon-γ-induced GTP-binding protein: the human guanylate binding protein, huGBP-1. J. Leukocyte Biol. 60, 423-431.
33. VESTAL, D.J., BUSS, J.E., KELNER, G.S., MACIEJEWSKI, D., ASUNDI, V.K., and MAKI, R.A. (1996). Rat p67 GBP is induced by interferon-gamma and isoprenoid modified in macrophages. Biochem. Biophys. Res. Commun. 224, 528-534.
34. GUPTA, S.L., RUBIN, B., and HOLMES, S.L. (1979). Interferon action: induction of specific proteins in mouse and human cells by homologous interferons. Proc. Natl. Acad. Sci. USA 76, 4817-4821.
35. CELADA, A., GRAY, P.W., RINDERKNEHT, E., and SCHREIBER, R.D. (1984). Evidence for a gamma-interferon receptor that regulates macrophage tumoricidal activity. J. Exp. Med. 160, 1937-1942.
36. ASUNDI, V.K., STAHL, R.C., SHOWALTER, L., CONNER, K.J., and CAREY, D.J. (1994). Molecular cloning and characterization of an isoprenylated 67 kDa protein. Biochim. Biophys. Acta 1217, 257-265.
37. BERGER, S.L., CHIRGWIN, J.M., MACDONALD, R.J., SWIFT, G.H., PRZYBYLA, A.E., and CHIRGWIN, J.M. (1989). Isolation of RNA using guanidinium salts. Methods Enzymol. 180, 3-13.
38. VESTAL, D.J., MAKI, R.A., and BUSS, J.E. (1995). Induction of a prenylated 65-kD protein in macrophages by interferon or lipopolysaccharide. J. Leukocyte Biol. 58, 607-615.
39. CRICK, D.C., ANDRES, D.A., and WAECHTER, C.J. (1995). Farnesol is utilized for protein isoprenylation and the biosynthesis of cholesterol in mammalian cells. Biochem. Biophys. Res. Commun. 211, 590-599.
40. CRICK, D.C., WAECHTER, C.J., and ANDRES, D.A. (1994). Utilization of geranylgeraniol for protein isoprenylation in C6 glial cells. Biochem. Biophys. Res. Commun. 205, 955-961.
41. CASEY, P.J., SOLSKI, P.A., DER, C.J., and BUSS, J.E. (1989). p21 Ras is modified by the isoprenoid famesol. Proc. Natl. Acad. Sci. USA 86, 8323-8327.
42. COPELAND, N.G., and JENKINS, N.A. (1991). Development and applications of a molecular genetic linkage map of the mouse genome. Trends Genet. 7, 113-118.
43. JENKINS, N.A., COPELAND, N.G., TAYLOR, B.A., and LEE, B.K. (1982). Organization, distribution, and stability of endogenous ecotropic murine leukemia virus DNA sequences in chromosomes of Mus musculus. J. Virol. 43, 26-36.
44. HAMEL, C.P., JENKINS, N.A., GILBERT, D.J., COPELAND, N.G., and REDMOND, T.M. (1994). The gene for the retinal pigment epithelium-specific protein RPE65 is localized to human 1 p31 and mouse 3. Genomics 20, 509-512.
45. GOLDSTEIN, J.L., and BROWN, M.S. (1990). Regulation of the mevalonate pathway. Nature 343, 425-430.
46. KATO, K., COX, A.D., HISAKA, M.H., GRAHAM, S.M., BUSS, J.E., and DER, C.J. (1992). Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity. Proc. Natl. Acad. Sci. USA 89, 6403-6407.
47. DER, C.J., and COX, A.D. (1991). Isoprenoid modification and plasma membrane association: critical factors for ras oncogenicity. Cancer Cells 3, 331-340.
48. JACKSON, J.H., LI, J.W., BUSS, J.E., DER, C.J., and COCHRANE, C.G. (1994). Polylysine domain of K-ras 4B protein is crucial for malignant transformation. Proc. Natl. Acad. Sci. USA 91, 12730-12734.
49. BIGAY, J., FAUROBERT, E., FRANCO, M., and CHABRE, M. (1994). Roles of lipid modifications of transducin subunits in their GDP-dependent association and membrane binding. Biochemistry 33, 14081-14090.
50. BOGUSKI, M.D., and MCCORMICK, F. (1993). Proteins regulating Ras and its relatives. Nature 366, 643-654.
51. LIPMAN, D.J., and PEARSON, W.R. (1985). Rapid and sensitive proteins similarity searches. Science 227, 1435-1441.
52. JACKSON, J.H., COCHRANE, C.G., BOURNE, J.R., SOLSKI, P.A., BUSS, J.E., and DER, C.J. (1990). Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation. Proc. Natl. Acad. Sci. USA 87, 3042-3046.
53. TAKAI, Y., KAIBUCHI, K., KIKUCHI, A., SASAKI, T., and SHIRATAKI, H. (1993). Regulators of small GTPases. Ciba Found. Symp. 176, 128-138; discussion 138-146.
54. ULLRICH, O., STENMARK, H., ALEXANDROV, K., HUBER, L.A., KAIBUCHI, K., SASAKI, T., TAKAI, Y., and ZERIAL, M. (1993). Rab GDP dissociation inhibitor as a general regulator for the membrane association of Rab proteins. J. Biol. Chem. 268, 18143-18150.
55. PFEFFER, S.R., DIRAC-SVEJSTRUP, A.G., and SOLDATI, T. (1995). Rab GDP dissociation inhibitor: putting Rab GTPases in the right place. J. Biol. Chem. 270, 17057-17059.
56. MARSHALL, C.J. (1993). Protein prenylation: a mediator of protein-protein interactions. Science 259, 1865-1866.
57. RUBINSTEIN, M., NOVICK, D., and FISCHER, D.G. (1987). The human interferon-γ receptor system. Immunol. Rev. 97, 29-32.