Treatment of chronic suppurative otitis media with topical ciprofloxacin

Annals of Otology, Rhinology and Laryngology

Volumn 107, Issue 10 II, 1998, Pages 865-871

  Alper, Cuneyt M ^a   Casselbrant, Margaretha L ^a   Dohar, Joseph E ^a   Rose, Elizabeth A McI ^b   Kenna, Margaret A ^c   Doyle, William J ^a   Bluestone, Charles D ^a  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b ROYAL CHILDREN'S HOSPITAL   (Australia)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Chronic suppurative otitis media; Ciprofloxacin; Otorrhea

Indexed keywords

CIPROFLOXACIN; CORTISPORIN; EAR DROPS;

ANIMAL MODEL; ANTIBIOTIC THERAPY; ARTICLE; CHRONIC OTITIS MEDIA; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; FEMALE; MALE; NONHUMAN; OTORRHEA; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; STATISTICAL ANALYSIS; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ANIMALS; ANTI-INFECTIVE AGENTS; CHRONIC DISEASE; CIPROFLOXACIN; DISEASE MODELS, ANIMAL; DRUG COMBINATIONS; HUMANS; HYDROCORTISONE; MACACA FASCICULARIS; NEOMYCIN; OTITIS MEDIA, SUPPURATIVE; POLYMYXIN B; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; TREATMENT OUTCOME;

EID: 0031670593     PISSN: 00034894     EISSN: None     Source Type: Journal    
DOI: 10.1177/000348949810701010     Document Type: Article

References (34)

1. Korvick J, Yu VL, Hilf M. Susceptibility of 100 blood isolates of P aeruginosa to 19 antipseudomonal antibiotics: old and new. Diagn Microbiol Infect Dis 1987;7:107-11.
2. Wright CG, Meyerhoff WL, Halama AR. Ototoxicity of neomycin and polymyxin B following middle ear application in the chinchilla and baboon. Am J Otol 1987;8:495-9.
3. Meyerhoff WL, Morizono T, Wright CG, Shaddock LC, Shea DA, Sikora MA. Tympanostomy tubes and otic drops. Laryngoscope 1983;93:1022-7.
4. Yu VL, Vickers RM, Zuravleff JJ. Comparative susceptibilities to moxalactam and eight other antipseudomonal antimicrobial agents (old and new). Antimicrob Agents Chemother 1980;17:96-8.
5. Dohar JE, Kenna MA, Wadowsky RM. In vitro susceptibility of aural isolates of P aeruginosa to commonly used ototopical antibiotics. Am J Otol 1996;17:207-9.
6. Dohar JE, Kenna MA, Wadowsky RM. Therapeutic implications in the treatment of aural Pseudomonas infections based on in vitro susceptibility patterns. Arch Otolaryngol Head Neck Surg 1995;121:1022-5.
7. Neu HC, ed. Ciprofloxacin monograph. Leverkussen, Germany: Bayer AG, 1992.
8. Hooper DC, Wolfson JS. Fluoroquinolone antimicrobial agents. N Engl J Med 1991;324:384-94.
9. Garcia-Rodriguez JA, del Canizo A, Garcia Sanchez JE, et al. Efficacy of 2 regimens of local ciprofloxacin in the treatment of ear infections. Drugs 1993;45(suppl 3):40-1.
10. Esposito S, D'Errico G, Montanaro C. Topical and oral treatment of chronic otitis media with ciprofloxacin. A preliminary study. Arch Otolaryngol Head Neck Surg 1990;116:557-9.
11. Piccirillo JF, Parnes SM. Ciprofloxacin for the treatment of chronic ear disease. Laryngoscope 1989;99:510-3.
12. Gough A, Barsoum NJ, Mitchell L, McGuire EJ, de la Iglesia FA. Juvenile canine drug-induced arthropathy: clinicopathological studies on articular lesions caused by oxolinic and pipemidic acids. Toxicol Appl Pharmacol 1979;51:177-87.
13. Christ W, Lehnert T, Ulbrich B. Specific toxicologic aspects of the quinolones. Rev Infect Dis 1988;10(suppl 1):S141-S146.
14. Stahlmann R, Merker HJ, Hinz N, Chahoud I, Webb J, Heger W. Ofloxacin in juvenile nonhuman primates and rats: arthropathia and drug plasma concentrations. Arch Toxicol 1990;64:193-204.
15. Schaad US, Sander E, Wedgwood J, Schaffner T. Morphologic studies for skeletal toxicity after prolonged ciprofloxacin therapy in two juvenile cystic fibrosis patients. Pediatr Infect Dis J 1992;11:1047-9.
16. Schaad US, Stoupis C, Wedgwood J, Tschaeppler H, Vock P. Clinical, radiologie and magnetic resonance monitoring for skeletal toxicity in pediatric patients with cystic fibrosis receiving a three-month course of ciprofloxacin. Pediatr Infect Dis J 1991;10:723-9.
17. Chysky V, Kapila K, Hullman R, Arcieri G, Schacht P, Echols R. Safety of ciprofloxacin in children: worldwide clinical experience based on compassionate use. Emphasis on joint evaluation. Infection 1991;4:289-96.
18. Gardner PV, Roberts SD, Bell AL. Cystic fibrosis and rheumatoid arthritis. Br J Rheumatol 1989;28:179.
19. Anderson RG, Wright CG, Meyerhoff WL. Inflammatory effects of otic drops on the middle ear. Int J Pediatr Otorhinolaryngol 1984;7:91-5.
20. Brummett RE, Harris RF, Lindgren JA. Detection of ototoxicity from drugs applied topically to the middle ear space. Laryngoscope 1976;86:1177-87.
21. Ikeda I, Morizono T. The preparation of acetic acid for use in otic drops and its effect on endocochlear potential and pH in inner ear fluid. Am J Otolaryngol 1989;10:382-5.
22. Murphy KW. Deafness after topical neomycin. Br Med J 1970;2:114.
23. Parker FL, James G. The effect of various topical antibiotic and antibacterial agents on the middle and inner ear of the guinea pig. J Pharm Pharmacol 1978;30:236-9.
24. Stupp H, Kupper K, Lagler F, Sous H, Quante M. Inner ear concentrations and ototoxicity of different antibiotics in local and systemic application. Audiology 1973;12:350-63.
25. Wright CG, Halama AR, Meyerhoff WL. Ototoxicity of an ototopical preparation in a primate. Am J Otol 1987;8:56-60.
26. Wright CG, Meyerhoff WL. Ototoxicity of otic drops applied to the middle ear of the chinchilla. Am J Otolaryngol 1984;5:166-76.
27. Wright CG, Meyerhoff WL, Burns DK. Middle ear cholesteatoma: an animal model. Am J Otolaryngol 1985;6:327-41.
28. Fausti SA, Rappaport BZ, Schechter MA, Frey RH, Ward TT, Brummett RE. Detection of aminoglycoside ototoxicity by high frequency auditory evaluation: selected case studies. Am J Otolaryngol 1984;5:177-82.
29. Bagger-Sjoback D, Lundman L, Nilsson-Ehrle I. Ciprofloxacin and the inner ear - a morphological and round window membrane permeability study. ORL J Otorhinolaryngol Relat Spec 1992;54:5-9.
30. Robson MC, Stenberg BD, Heggers JP. Wound healing alterations caused by infection. Clin Plast Surg 1990;17:485-92.
31. Laato M, Niinikoski C, Lundberg B, Gerdin B. Inflammatory reaction and blood flow in experimental wounds inoculated with Staphylococcus aureus. Eur Surg Res 1988;20:33-8.
32. Laato M, Lehtonen P, Niinikoski J. Granulation tissue formation in experimental wounds inoculated with Staphylococcus aureus. Acta Chir Scand 1985;151:313-8.
33. Tenorio A, Jindrak K, Weiner M, Bella E, Enquist IF. Accelerated healing in infected wounds. Surg Gynecol Obstet 1976;142:537-43.
34. Polansky JR, Fauss DJ, Nguyen TD. Ophthalmic corticosteroids and steroid glaucoma mechanisms. Ophthalmol Clin North Am 1995;8:215-28.