Plasma and urinary levels of adrenomedullin in chronic glomerulonephritis patients with proteinuria

Nephron

Volumn 80, Issue 2, 1998, Pages 227-230

  Kubo, Atsushi ^a,b   Kurioka, Hideyuki ^a   Minamino, Naoto ^b   Nishitani, Yoshiharu ^a   Sato, Hiroaki ^a   Nishino, Toshihiko ^a   Iwano, Masayuki ^a   Shiiki, Hideo ^a   Kangawa, Kenji ^b   Matsuo, Hisayuki ^b   Dohi, Kazuhiro ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

^b NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Adrenomedullin; Focal segmental glomerulosclerosis; Glomerulonephritis; Membranous nephropathy; Minimal change nephrotic syndrome; Plasma; Urine

Indexed keywords

ADRENOMEDULLIN;

ADULT; ARTICLE; CHRONIC GLOMERULONEPHRITIS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; FOCAL GLOMERULOSCLEROSIS; HUMAN; HUMAN TISSUE; KIDNEY DISEASE; MINIMAL CHANGE GLOMERULONEPHRITIS; NEPHROTIC SYNDROME; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN URINE LEVEL; PROTEINURIA; RADIOIMMUNOASSAY; URINARY EXCRETION;

ADRENOMEDULLIN; ADULT; AGED; ANALYSIS OF VARIANCE; CASE-CONTROL STUDIES; GLOMERULONEPHRITIS; GLOMERULONEPHRITIS, MEMBRANOUS; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; HUMANS; MIDDLE AGED; NEPHROTIC SYNDROME; PEPTIDES; PROTEINURIA; VASODILATOR AGENTS;

EID: 0031669813     PISSN: 00282766     EISSN: None     Source Type: Journal    
DOI: 10.1159/000045172     Document Type: Article

References (16)

1. Kitamura K, Kangawa K, Kawamoto M, Ichiki Y, Nakamura S, Matsuo H, Eto T: Adrenomedullin: A novel hypotension peptide isolated from human pheochromocytoma. Biochem Biophys Res Commun 1993;192:553-560.
2. Kitamura K, Sakata J, Kangawa K, Kojima M, Matsuo H, Eto T: Cloning and characterization of cDNA encoding a precursor for human adrenomedullin. Biochem Biophys Res Commun 1993;194:720-725.
3. Jougasaki M, Wei C-M, Aarhus LL, Heublein DM, Sandberg SM, Burnett JC Jr. Renal localization and actions of adrenomedullin: A natriuretic peptide. Am J Physiol 1995;268:F657-F663.
4. Chini EN, Chini CCS, Bolliger C, Jougasaki M, Grande JP, Burnett JC, Dousa TP: Cytoprotective effects of adrenomedullin in glomerular cell injury: Central role of cAMP signaling pathway. Kidney Int 1997;52:917-925.
5. Kubo A, Iwano M, Minamino N, Sato H, Nishino T, Hirata E, Akai Y, Shiiki H, Kitamura K, Kangawa K, Matsuo H, Dohi K: Measurement of plasma and urinary adrenomedullin in patients with IgA nephropathy. Nephron 1998;78:389-394.
6. Glossock RJ, Cohen AH, Adler SG: Primary glomerular disease; in Brenner BM (ed): The Kidney. Philadelphia, Saunders, 1996, vol II, pp 1392-1497.
7. Ishimitu T, Nishikimi T, Kitamura K, Eto T, Kangawa K, Matsuo H, Omae T, Matsuoka H: Plasma levels of adrenomedullin, a newly identified hypotensive peptide, in patients with hypertension and renal failure. J Clin Invest 1994;94:2158-2161.
8. Nishikimi T, Saito S, Kitamura K, Ishimitu T, Eto T, Kangawa K, Matsuo H, Omae T, Matsuoka H: Increased plasma levels of adrenomedullin in patients with heart failure. J Am Coll Cardiol 1995;26:1424-1431.
9. Eto T, Washimine H, Kato J, Kitamura K, Yamamoto Y: Adrenomedullin and proadrenomedullin N-terminal 20 peptide in impaired renal function. Kidney Int 1996;49(suppl 55):148-149.
10. Ebra T, Miura K, Okumura M, Matsuura T, Kim S, Yukimura T, Iwao H: Effect of adrenomedullin on renal hemodynamics and functions in dogs. Eur J Pharmacol 1994;263:69-73.
11. Hirata Y, Hayakawa H, Suzuki Y, Suzuki E, Ikenouchi H, Kohmoto O, Kimura K, Kitamura K, Eto T, Kangawa K, Matsuo H, Omata M: Mechanism of adrenomedullin in the rat kidney. Hypertension 1995;25:790-795.
12. Vari RC, Adkins SD, Samson WK: Renal effect of adrenomedullin in the rat. Proc Soc Exp Biol Med 1996;211:178-183.
13. Schell DA, Vari RC, Samson WK: Adrenomedullin: A newly discovered hormone controlling fluid and electrolyte homeostasis. Trends Endocrinol Metab 1996;7:7-13.
14. Sato K, Hirata Y, Imai T, Iwashita M, Maruo F: Characterization of immunoreactive adrenomedullin in human plasma and urine. Life Sci 1995;57:189-194.
15. Sato K, Imai T, Iwashina M, Marumo F, Hirata Y: Secretion of adrenomedullin by renal tubular cell lines. Nephron 1998;78:9-14.
16. Chini EN, Choi E, Grande JP, Burnet JC, Dousa TP: Adrenomedullin suppresses mitogenesis in rat mesangial cells via cAMP pathway. Biochem Biophys Res Commun 1995;215:868-873.