Effect of simulated microgravity on vascular contractility

Journal of Applied Physiology

Volumn 85, Issue 4, 1998, Pages 1307-1315

  Purdy, R E ^a   Duckles, S P ^a   Krause, D N ^a   Rubera, K M ^a   Sara, D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Blood vessels; Norepinephrine; Potassium; Rat

Indexed keywords

NORADRENALIN; POTASSIUM;

ABDOMINAL AORTA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL REACTIVITY; CAROTID ARTERY; CONTROLLED STUDY; FEMORAL ARTERY; FEMORAL VEIN; JUGULAR VEIN; MALE; MICROGRAVITY; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PRIORITY JOURNAL; RAT; SIMULATION; STRAIN DIFFERENCE;

EID: 0031668743     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1998.85.4.1307     Document Type: Article

References (32)

1. Besse, J. C., and R. F. Furchgott. Dissociation constants and relative efficacies of agonists acting on alpha adrenergic receptors in rabbit aorta. J. Pharmacol. Exp. Ther. 197: 66-78, 1976.
2. Bevan, J. A., and J. V. Osher. A direct method for recording tension changes in the wall of small blood vessels in vitro. Agents Actions 2: 257-260, 1972.
3. Bungo, M. W., and P. C. Johnson. Cardiovascular examinations and observations of deconditioning during the Space Shuttle orbital test program. Aviat. Space Environ. Med. 54: 1001-1004, 1983.
4. Charles, J. B., and C. M. Lathers. Cardiovascular adaptation to spaceflight. J. Clin. Pharmacol. 31: 1010-1024, 1991.
5. 2 receptor mechanisms in rat jugular veins: differences between norepinephrine and isoproterenol-induced relaxation. Life Sci. 24: 1997-2006, 1978.
6. Delp, M. D., M. Brown, M. H. Laughlin, and E. M. Hasser. Rat aortic vasoreactivity is altered by old age and hindlimb unloading. J. Appl. Physiol. 78: 2079-2086, 1995.
7. Delp, M. D., T. Holder-Binkley, M. H. Laughlin, and E. M. Hasser. Vasoconstrictor properties of rat aorta are diminished by hindlimb unweighting. J. Appl. Physiol. 75: 2620-2628, 1993.
8. Dunn, C. D. R., P. C. Johnson, and R. D. Lange. Regulation of hematopoiesis in rats exposed to antiorthostatic hypkinetic/ hypodynamia. II. Mechanisms of the "anemia." Aviat. Space Environ. Med. 57: 36-44, 1986.
9. Edgerton, V. R., and R. R. Roy. Neuromuscular adaptations to actual and simulated spaceflight. In: Handbook of Physiology. Environmental Physiology. Bethesda, MD: Am. Physiol. Soc., 1996, sect. 4, vol. I, pt. 3, chapt. 32, p. 721-763.
10. Fagette, S., M. Lo, C. Gharib, and G. Gauquelin. Cardiovascular variability and baroreceptor reflex sensitivity over a 14-day tail suspension in rats. J. Appl. Physiol. 78: 717-724, 1995.
11. Fritsch, J. M., J. B. Charles, B. S. Bennett, M. M. Jones, and D. L. Eckberg. Short-duration spaceflight impairs human carotid baroreceptor-cardiac reflex responses. J. Appl. Physiol. 73: 664-674, 1992.
12. Furchgott, R. F. The classification of adrenoceptors (adrenergic, receptors). An evaluation from the standpoint of receptor theory. In: Catecholamines, edited by H. Blaschko and E. Muscholl. Berlin: Springer-Verlag, 1972, vol. 33, p. 283-335.
13. Glen, J. B., and W. N. Scott. Carbon dioxide euthanasia of cats. Br. Vet. J. 129: 471-479, 1973.
14. Hargens, A. R., D. E. Watenpaugh, and G. A. Breit. Control of circulatory function in altered gravitational fields. Physiologist 35, Suppl.: S80-S83, 1992.
15. Johnson, S. M., and I. S. de la Lande. Action of deoxycorticosterone acetate on the central artery of the rabbit ear. Blood Vessels 15: 241-246, 1978.
16. Jones, M. M., and J. B. Charles. Human blood pressure and heart rate changes during space shuttle landing and crew egress (Abstract). FASEB J. 7: A665, 1993.
17. Kalsner, S. Steroid potentation of responses to sympathomimetic amines in aortic strips. Br. J. Pharmacol. 36: 582-593, 1969.
18. Li, Z., and S. P. Duckles. Acute effects of nicotine on rat mesenteric vasculature and tail artery. J. Pharmacol. Exp. Ther. 264: 1205-1210, 1993.
19. McDonald, K. S., M. D. Delp, and R. H. Fitts. Effect of hindlimb unweighting on tissue blood flow in the rat. J. Appl. Physiol. 72: 2210-2218, 1992.
20. Moore, T. P., and W. E. Thornton. Space shuttle inflight and postflight fluid shifts measured by leg volume changes. Aviat. Space Environ. Med. 58: A91-A96, 1987.
21. Mulvagh, S. L., J. B. Charles, J. M. Riddle, T. L. Rehbein, and M. W. Bungo. Echocardiographic evaluation of the cardiovascular effects of short-duration spaceflight. J. Clin. Pharmacol. 31: 1024-1026, 1991.
22. Overton, J. M., and C. M. Tipton. Effect of hindlimb suspension on cardiovascular responses to sympathomimetics and lower body negative pressure. J. Appl. Physiol. 68: 355-362, 1990.
23. 2max and regional blood flow responses to exercise. J. Appl. Physiol. 66: 653-659, 1989.
24. 1-adrenoceptors in rat vena cava. J. Appl. Physiol. 78: 1882-1888, 1995.
25. Shellock, F. G., H. J. C. Swan, and S. A. Rubin. Early central venous pressure changes in the rat during two different levels of head-down suspension. Aviat. Space Environ. Med. 56: 791-795, 1985.
26. Spengler, D. M., E. R. Morey, D. R. Carter, R. T. Turner, and D. J. Baylink. Effects of spaceflight on structural and material strength of growing bone. Proc. Soc. Exp. Biol. Med. 174: 224-228, 1983.
27. Sprenkle, J. M., D. L. Eckberg, R. L. Goble, J. J. Schelhorn, and H. C. Halliday. Device for rapid quantification of human carotid baroreceptor-cardiac reflex responses. J. Appl. Physiol. 60: 727-732, 1986.
28. Thomason, D. B., R. E. Herrick, D. Surdyka, and K. M. Baldwin. Time course of soleus muscle myosin expression during hindlimb suspension and recovery. J. Appl. Physiol. 63: 130-137, 1987.
29. Vaziri, N. D., X. J. Zhou, J. Smith, F. Oveisi, K. Baldwin, and R. Purdy. In vivo and in vitro pressor effects of erythropoietin in rats. Am. J. Physiol. 269 (Renal Fluid Electrolyte Physiol. 38): F838-F845, 1995.
30. Vogel, J. M., and M. W. Whittle. Bone mineral content changes in the Skylab astronauts. Am. J. Roentgenol. 126: 1296-1297, 1976.
31. Watenpaugh, D. E., and A. R. Hargens. The cardiovascular system in microgravity. In: Handbook of Physiology. Environmental Physiology. Bethesda, MD: Am. Physiol. Soc., 1996, sect. 4, vol. I, pt. 3, chapt. 29, p. 631-674.
32. Weber, M. A., R. E. Purdy, G. L. Stupecky, and B. A. Prins. Augmentation of sympathomimetic arterial contraction by angiotensin II: a novel mechanism. J. Vasc. Med. Biol. 1: 7-12, 1989.