Therapeutic efficacy of vinorelbine against pediatric and adult central nervous system tumors

Cancer Chemotherapy and Pharmacology

Volumn 42, Issue 6, 1998, Pages 479-482

  Hanley, Matthew L ^a   Elion, Gertrude B ^a   Colvin, O Michael ^a   Modrich, Paul L ^a   Keir, Stephen ^a   Adams, David J ^a   Bigner, Darell D ^a   Friedman, Henry S ^a  

^a DUKE UNIVERSITY   (United States)

Author keywords

CNS tumors; Mismatch repair; Vinca alkaloid; Vinorelbine; Xenografts

Indexed keywords

CARMUSTINE; NAVELBINE; PACLITAXEL; PROCARBAZINE; VINCRISTINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CENTRAL NERVOUS SYSTEM TUMOR; CHILDHOOD CANCER; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; EPENDYMOMA; FEMALE; GLIOMA; HUMAN; HUMAN TISSUE; INTRAPERITONEAL DRUG ADMINISTRATION; MEDULLOBLASTOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR REGRESSION; TUMOR XENOGRAFT; WEIGHT REDUCTION;

ADULT; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BRAIN NEOPLASMS; CHILD; FEMALE; GLIOMA; HUMANS; MICE; MICE, INBRED BALB C; NEOPLASM TRANSPLANTATION; VINBLASTINE;

EID: 0031668233     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050848     Document Type: Article

References (14)

1. Adams DJ, Knick VC (1995) P-glycoprotein mediated resistance to 5′-nor-anhydro-vinblastine (Navelbine). Invest New Drugs 13: 13
2. Binet S, Fellous A, Lataste H, Krikorian A, Couziner JP, Meininger V (1989) In situ analysis of the action of Navelbine on various types of microtubules using immunofluorescence. Semin in Oncol 16: 5
3. Boring CC, Squires TS, Tong T (1993) Cancer statistics. CA Cancer J Clin 43: 7
4. Bullard DE, Schold SC Jr, Bigner SH, Bigner DD (1981) Growth and chemotherapeutic response in athymic mice of tumors arising from human glioma-derived cell line. J Neropathol Exp Neurol 40: 410
5. Burris HA III, Fields S (1994) Summary of data from in vitro and phase I vinorelbine (Navelbine) studies. Semin in Oncol 21: 14
6. Burroughs Wellcome Co., Navelbine investigators brochure, 12. Sept 1993
7. Friedman HS, Colvin OM, Skapek SX, Ludeman SM, Elion GB, Schold SC Jr, Jacobsen PF, Muhlbaier LH, Bigner DD (1988) Experimental chemotherapy of human medulloblastoma cell lines and transplantable xenografts with bifunctional alkylating agents. Cancer Res 48: 4189
8. Friedman HS, Horowitz ME, Oakes WJ (1991) Tumors of the central nervous system. Improvement in outcome through a multi-modality approach. Pediatr Clin North Am 38: 381
9. Friedman HS, Houghton PJ, Schold SC, Keir S, Bigner DD (1994) Activity of 9-dimethylaminomethyl-10-hydroxycamptothecin against pediatric and adult central nervous system tumors xenografts. Cancer Chemother Pharmacol 34: 171
10. Friedman HS, Johnson SP, Dong Q, Schold SC, Rasheed BK, Bigner SH, Ali-Osman F, Dolan E, Colvin OM, Houghton P, Germaine G, Drummond JT, Keir S, Marcelli S, Bigner DD, Modrich P (1997) Methylator resistance mediated by mismatch repair deficiency in a glioblastoma multiforme xenograft. Cancer Res 57: 2933
11. Knick VC, Miler CG (1992) Invitro derivation of a murine P388 leukemia subline resistant to 5′ nor-anhydrovinblastine (navelbine) and its cross resistance profile (abstract). Proc Am Assoc Cancer Res 33: 462
12. Potier P (1989) The systhesis of Navelbine prototype of a new series of vinblastine derivatives. Semin Oncol 16: 2
13. 6-alkylguanine-DNA alkyltransferase and sensitivity to procarbazine in human brain tumor xenografts. J Neurosurg 70: 573
14. Schold CS, Burger PC, Mendelsohn DB, Glatstein EJ, Mickey BC, Minna JD (1997) Primary tumors of the brain and spinal cord. Butterworth-Heinemann, Newton, Mass.