Genotoxicity in workers exposed to methyl bromide

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 417, Issue 2-3, 1998, Pages 115-128

  Calvert, Geoffrey M ^a   Talaska, Glenn ^a,c   Mueller, Charles A ^a   Ammenheuser, Marinel M ^b   Au, William W ^b   Fajen, John M ^a   Fleming, Lora E ^d   Briggle, Thomas ^d   Ward, Elizabeth ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Biological marker; Fumigation; hprt mutation; Methylbromide; Micronucleus; Mutagenicity test; Smoking

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; METHYL BROMIDE;

ARTICLE; CHROMOSOME DAMAGE; CONTROLLED STUDY; GENE MUTATION; GENOTOXICITY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; INFECTION CONTROL; LYMPHOCYTE; MICRONUCLEUS TEST; NORMAL HUMAN; PRIORITY JOURNAL; SISTER CHROMATID EXCHANGE;

ADULT; AGED; CHROMOSOME ABERRATIONS; HUMANS; HYDROCARBONS, BROMINATED; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; INHALATION EXPOSURE; LYMPHOCYTES; MALE; MICRONUCLEUS TESTS; MIDDLE AGED; MUTATION; OCCUPATIONAL EXPOSURE; OROPHARYNX; PESTICIDES; REGRESSION ANALYSIS;

EID: 0031667689     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(98)00105-3     Document Type: Article

References (53)

1. Anonymous, Methyl bromide under fire, Environ. Health. Perspect. 102 (1994) 732-733.
2. NIOSH, National occupational exposure survey, DHHS (NIOSH) Publication Number 89-103, US Department of Health and Human Services, Washington, DC, March 1988.
3. ATSDR, Toxicological profile for bromomethane, DHHS (ATSDR) Publication Number, TP-91/06, US Department of Health and Human Services, Washington, DC, September 1992.
4. G. Djalali-Behzad, S. Hussain, S. Osterman-Golkar, D. Segerback, Estimation of genetic risks of alkylating agents: VI. Exposure of mice and bacteria to methyl bromide, Mutat. Res. 84 (1981) 1-9.
5. N. Ikawa, A. Araki, K. Nozaki, T. Matsushima, Micronucleus test of methyl bromide by the inhalation method, Mutat. Res. 164 (1986) 269, Abstract.
6. D.B. McGregor, Tier II mutagenic screening of 13 NIOSH priority compounds: individual compound report methyl bromide, Report to NIOSH, Cincinnati, OH, by Inveresk Research International, Musselburgh, Scotland, NTIS No. PB83-130211, 1981.
7. J. Battey, C. Moulding, R. Taub, W. Murphy, T. Stewart, H. Potter, G. Lenoir, P. Leder, The human c-myc oncogene: structural consequences of translocation into the IgH locus in Burkitt's lymphoma, Cell 34 (1983) 779-787.
8. D. Bizub, A.W. Wood, A.M. Skala, Mutagenesis of the Ha-ras oncogene in mouse skin tumors induced by polycyclic aromatic hydrocarbons, Proc. Natl. Acad. Sci. 83 (1986) 6048-6052.
9. L.H. Danse, F.L. van Velson, C.A. van der Heijden, Methylbromide: carcinogenic effects in the rat forestomach, Toxicol. Appl. Pharmacol. 72 (1984) 262-271.
10. G.A. Boorman, H.L. Hong, C.W. Jameson, K. Yoshitomi, R.R. Maronpot, Regression of methyl bromide-induced forestomach lesions in the rat, Toxicol. Appl. Pharmacol. 86 (1986) 131-139.
11. P.G.J. Reuzel, H.C. Dreef-van Der Meulen, V.M.H. Hollanders, C.F. Kuper, V.J. Feron, C.A. van der Heijden, Chronic inhalation toxicity and carcinogenicity study of methyl bromide in Wistar rats, Food Chem. Toxicol. 29 (1991) 31-39.
12. K. Gotoh, T. Nishizawa, T. Yamaguchi, H. Kanou, T. Kasai, M. Ohsawa, H. Ohbayashi, S. Aiso, N. Ikawa, S. Yamamoto, T. Noguchi, K. Nagano, M. Enomoto, K. Nozaki, H. Sakabe, Two-year toxicological and carcinogenesis studies of methylbromide in F344 rats and BDF1 mice, in: K. Sumino (Ed.), Proceedings of the 2nd Asia-Pacific Symposium on Environmental and Occupational Health, 22-24 July 1993, Kobe, Japan, International Center for Medical Research Kobe University School of Medicine, 1994, pp. 185-191.
13. NIOSH, Current Intelligence Bulletin 43, Monohalomethanes, Department of Health and Human Services (NIOSH) Publication 84-117, 1984.
14. 1 mice (inhalation studies), NTP Technical Report No. 363, NIH Publication No. 89-2818, Research Triangle Park, NC and Bethesda, MD, 1989.
15. 1 mice (inhalation studies), NTP Technical Report No. 346, NIH Publication No. 90-2801, Research Triangle Park, NC and Bethesda, MD, 1989.
16. V.F. Garry, R.L. Nelson, J. Griffith, M. Harkins, Preparation for human study of pesticide applicators: sister chromatid exchanges and chromosome aberrations in cultured human lymphocytes exposed to selected fumigants, Teratog. Carcinog. Mutagen. 10 (1990) 21-29.
17. G.M. Calvert, C.A. Mueller, J.M. Fajen, D.W. Chrislip, J. Russo, T. Briggle, L.E. Fleming, A.J. Suruda, K. Steenland, Health effects associated with sulfuryl fluoride and methyl bromide exposure among structural fumigation workers, Am. J. Public Health, 1998, in press.
18. R.J. Albertini, Somatic gene mutations in vivo as indicated by the 6-thioguanine-resistant T-lymphocytes in human blood, Mutat. Res. 150 (1985) 411-422.
19. M.M. Ammenheuser, A.B. Berenson, A.E. Babiak, C.R. Singleton, E.B. Whorton, Frequencies of hprt mutant lymphocytes in marijuana-smoking mothers and their newborns, Mutat. Res. 403 (1998) 55-64.
20. M.M. Ammenheuser, D.A. Hastings, E.B. Whorton Jr., J.B. Ward Jr., Frequencies of Hprt mutant lymphocytes in smokers, non-smokers, and former smokers, Environ. Mol. Mutagen. 30 (1997) 131-138.
21. J.A. Nicklas, J.P. O'Neill, L.M. Sullivan, T.C. Hunter, M. Allegretta, B.F. Chastenay, B.L. Libbus, R.J. Albertini, Molecular analyses of in vivo hypoxanthine-guanine phosphoribosyltransferase mutations in human T-lymphocytes: II. Determination of a clonal amplification of hprt mutant T-lymphocytes in vivo, Environ. Mol. Mutagen. 12 (1988) 271-284.
22. M. Fenech, The cytokinesis-block micronucleus technique: a detailed description of the method and its application to genotoxicity studies in human populations, Mutat. Res. 285 (1993) 35-44.
23. W.W. Au, D.M. Walker, J.B. Ward, E. Whorton, M.S. Legator, V. Singh, Factors contributing to chromosome damage in lymphocytes of cigarette smokers, Mutat. Res. 260 (1991) 137-144.
24. D.A. Eastmond, J.D. Tucker, Identification of aneuploidy-inducing agents using cytokinesis-blocked human lymphocytes and an anti-kinetochore antibody, Environ. Mol. Mutagen. 13 (1989) 34-43.
25. G.M. Calvert, C.A. Mueller, V.L. O'Neill, J.M. Fajen, T. Briggle, L.E. Fleming, Agreement between company-recorded and self-reported estimates of duration and frequency of occupational fumigant exposure, Am. J. Ind. Med. 32 (1997) 364-368.
26. K. Messing, A.M. Seifert, W.E.C. Bradley, In vivo mutant frequency of technicians professionally exposed to ionizing radiation, in: M. Sorsa, H. Norppa (Eds.), Monitoring of Occupational Genotoxicants, Alan R. Liss, New York, 1986, pp. 87-97.
27. J.A. Nicklas, M.T. Falta, T.C. Hunter, J.P. O'Neill, D. Jacobson-Kram, J.R. Williams, R.J. Albertini, Molecular analysis of in vivo hprt mutations in human T-lymphocytes: V. Effects of total body irradiation secondary to radioim-munoglobin therapy (RIT), Mutagenesis 5 (1990) 461-468.
28. A.M. Seifert, C. Demers, H. Dubeau, K. Messing, HPRT-mutant frequency and lymphocyte characteristics of workers exposed to ionizing radiation on a sporadic basis: a comparison of two exposure indicators, job title and dose, Mutat. Res. 319 (1993) 61-70.
29. R.J. Albertini, D.L. Sylvester, B.D. Dannenberg, E.F. Allen, Mutation in vivo in human somatic cells: studies using peripheral blood mononuclear cells, in: R.A. Fleck, A. Hollaender (Eds.), Genetic Toxicology, Plenum, New York, 1982, pp. 403-424.
30. R.J. Albertini, J.A. Nicklas, J.C. Fuscoe, T.R. Skopek, R.F. Branda, J.P. O'Neill, In vivo mutations in human blood cells: biomarkers for molecular epidemiology, Environ. Health Perspect. 99 (1993) 135-141.
31. M.M. Ammenheuser, J.B. Ward Jr., E.B. Whorton, J.M. Killian, M.S. Legator, Elevated frequencies of 6-thioguanine-resistant lymphocytes in multiple sclerosis patients treated with cyclophosphamide: a prospective study, Mutat. Res. 204 (1988) 509-520.
32. M.M. Ammenheuser, W.W. Au, E.B. Whorton, J.A. Belli, J.B. Ward, Comparison of hprt variant frequencies and chromosome aberration frequencies in lymphocytes from radiotherapy and chemotherapy patients: a prospective study, Environ. Mol. Mutagen. 18 (1991) 126-135.
33. A.D. Tates, T. Grummt, M. Tornqvist, P.B. Farmer, F.J. van Dam, H. van Mossel, H.M. Schoemaker, S. Osterman-Golkar, C. Uebel, Y.S. Tang, A.H. Zwinderman, A.T. Natarajan, L. Ehrenberg, Biological and chemical monitoring of occupational exposure to ethylene oxide, Mutat. Res. 250 (1991) 483-497.
34. A.D. Tates, P.J. Boogaard, F. Darroudi, A.T. Natarajan, M.E. Caubo, N.J. van Sittert, Biological effect monitoring in industrial workers following incidental exposure to high concentrations of ethylene oxide, Mutat. Res. 329 (1995) 63-77.
35. J.B. Ward Jr., M.M. Ammenheuser, E.B. Whorton Jr., W.E. Bechtold, K.T. Kelsey, M.S. Legator, Biological monitoring for mutagenic effects of occupational exposure to butadiene, Toxicology 113 (1996) 84-90.
36. M.F. Vine, Micronuclei, in: B.S. Hulka, T.C. Wilcosky, J.D. Griffith (Eds.), Biological Markers, Oxford Univ. Press, New York, 1990, pp. 125-146.3
37. J.A. Heddle, M.C. Cimino, M. Hayashi, F. Romagna, M.D. Shelby, J.D. Tucker, P.H. Vanpary, J.T. MacGregor, Micronuclei as an index of cytogenetic damage: past,3 present, and future, Environ. Mol. Mutagen. 18 (1991) 277-291.
38. L.E. Moore, M.L. Warner, A.H. Smith, D. Kalman, M.T. Smith, Use of the fluorescent micronucleus assay to detect the genotoxic effects of radiation and arsenic exposure in exfoliated human epithelial cells, Environ. Mol. Mutagen. 27 (1996) 176-184.
39. H.F. Stich, M.P. Rosin, Quantitating the synergistic effect on smoking and alcohol consumption with the micronucleus test on human buccal mucosa cells, Int. J. Cancer 31 (1983) 305-308.
40. F. Sarto, R. Tomanin, L. Giacomelli, G. Iannini, A.R. Cupiraggi, The micronucleus assay in human exfoliated cells of the nose and mouth: application to occupational exposures to chromic acid and ethylene oxide, Mutat. Res. 244 (1990) 345-351.
41. E. Fontham, 3 P. Correa, E. Rodriguez, Y. Lin, Validation of smoking history with the micronuclei test, in: D. Hoffmann, C.C. Harris (Eds.), Mechanisms in Tobacco Carcinogenesis, Banbury Report 23, 1986, pp. 113-119.
42. A. Forni, Comparison of chromosome aberrations and micronuclei in testing genotoxicity in humans, Toxicol. Lett. 72 (1994) 185-190.
43. C. Bolognesi, M. Parrini, F. Merlo, S. Bonassi, Frequency of micronuclei in lymphocytes from a group of floriculturists exposed to pesticides, J. Toxicol. Environ. Health 40 (1993) 405-411.
44. B. Hogstedt, B. Gullberg, K. Hedner, A. Kolnig, F. Mitelman, S. Skerfving, B. Widegren, Chromosome aberrations and micronuclei in bone marrow cells and peripheral blood lymphocytes in humans exposed to ethylene oxide, Hereditas 98 (1983) 105-113.
45. B. Hogstedt, Micronuclei in lymphocytes with preserved cytoplasm, Mutat. Res. 130 (1984) 63-72.
46. C. Di Giorgio, M.P. De Meo, M. Laget, H. Guiraud, A. Botta, G. Dumenil, The micronucleus assay in human lymphocytes: screening for inter-individual variability and application to biomonitoring, Carcinogenesis 15 (1994) 313-317.
47. J. Nath, J.D. Tucker, J.C. Hando, Y chromosome aneuploidy,3 micronuclei, kinetochores and aging in men, Chromosoma 103 (1995) 725-731.
48. M. Fenech, A.A. Morley, Kinetochore detection in micronuclei: an alternative method for measuring chromosome loss, Mutagenesis 4 (1989) 98-104.
49. Y. Gagnon, V. Ringenburg, J. Fajen, Problems with the NIOSH method 2520 for methyl bromide, Appl. Occup. Environ. Hyg. 9 (1994) 165-167.
50. Code of Federal Regulations 29 (July 1996), Subtitle B-Regulations relating to Labor, Part 1910, Table Z-1, Government Printing Office, Washington, DC, 1996.
51. E. Hallier, T. Langhof, D. Dannappel, M. Leutbecher, K. Schroder, H.W. Goergens, A. Muller, H.M. Bolt, Polymorphism of glutathione conjugation of methyl bromide, ethylene oxide and dichloromethane in human blood: influence on the induction of sister chromatid exchanges (SCE) in lymphocytes, Arch. Toxicol. 67 (1993) 173-178.
52. H.C. Pitot, Y.P. Dragan, Chemical carcinogenesis, in: C.D. Klaassen (Ed.), Casarett and Doull's Toxicology, 5th edn., McGraw-Hill, New York, 1996, pp. 201-267.
53. D.L. Eisenbrandt, K.D. Nitschke, Inhalation toxicity of sulfuryl fluoride in rats and rabbits, Fundam. Appl. Toxicol. 12 (1989) 540-557.