Effect of endurance training on cardiac morphology in Alaskan sled dogs

Journal of Applied Physiology

Volumn 85, Issue 4, 1998, Pages 1368-1375

  Stepien, R L ^a   Hinchcliff, K W ^b   Constable, P D ^c   Olson, J ^d  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d Raven Veterinary Services   (United States)

Author keywords

Athlete's heart; Dog; Echocardiography; Exercise; Left ventricular hypertrophy

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; DOG; ENDURANCE; FEMALE; FUNCTIONAL ASSESSMENT; HEART FUNCTION; M MODE ECHOCARDIOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; TRAINING; TWO DIMENSIONAL ECHOCARDIOGRAPHY;

EID: 0031667603     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1998.85.4.1368     Document Type: Article

References (71)

1. Barnard, R. J., K. Corre, and H. Cho. Effect of training on the resting heart rate of rats. Eur. J. Appl. Physiol. 35: 285-289, 1976.
2. Barnard, R. J., H. W. Duncan, K. M. Baldwin, G. Grimditch, and G. D. Buckberg. Effects of intensive exercise training on myocardial performance and coronary blood flow. J. Appl. Physiol. 49: 444-449, 1980.
3. Bjornstad, H., L. Storstein, H. D. Meen, and O. Hals. Ambulatory electrocardiographic findings in top athletes, athletic students and control subjects. Cardiology 84: 42-50, 1994.
4. Blomqvist, C. G., and B. Saltin. Cardiovascular adaptations to physical training. Annu. Rev. Physiol. 45: 169-189, 1983.
5. Bonagura, J. D., M. R. O'Grady, and D. S. Herring. Echocardiography. Principles of interpretation. Vet. Clin. North Am. Small Anim. Pract. 15: 1177-1194, 1985.
6. Carew, T. E., and J. W. Covell. Left ventricular function in exercise-induced hypertrophy in dogs. Am. J. Cardiol. 42: 82-88, 1978.
7. Clifford, P. S., B. Hanel, and N. H. Secher. Arterial blood pressure response to rowing. Med. Sci. Sports Exerc. 26: 715-719, 1994.
8. Colan, S. D., S. P. Sanders, D. MacPherson, and K. M. Borow. Left ventricular diastolic function in elite athletes with physiologic cardiac hypertrophy. J. Am. Coll. Cardiol. 6: 545-554, 1985.
9. Coleman, B., L. N. Cothran, E. L. Ison-Franklin, and E. W. Hawthorne. Estimation of left ventricular mass in conscious dogs. Am. J. Physiol. 251 (Heart Circ. Physiol. 20): H1149-H1157, 1986.
10. Constable, P. D., K. W. Hinchcliff, J. Olson, and R. L. Hamlin. Athletic heart syndrome in dogs competing in a long-distance sled race. J. Appl. Physiol. 76: 433-438, 1994.
11. Convertino, V. A. Blood volume: its adaptation to endurance training. Med. Sci. Sports Exerc. 23: 1338-1348, 1991.
12. Devereux, R. B. Detection of left ventricular hypertrophy of M-mode echocardiography. Anatomic validation, standardization, and comparison of other methods. Hypertension 9, Suppl. II: II-19-II-26, 1987.
13. Devereux, R. B., and N. Reichek. Echocardiographic determination of left ventricular mass in man. Circulation 55: 613-618, 1977.
14. Douglas, P. S., M. L. O'Toole, D. B. Hiller, and N. Reichek. Left ventricular structure and function by echocardiography in ultraendurance athletes. Am. J. Cardiol. 58: 805-809, 1986.
15. Fagard, R., A. Aubert, J. Staessen, E. Vanden Eynde, L. Vandees, and A. Amery. Cardiac structure and function in cyclists and runners. Comparative echocardiographic study. Br. Heart J. 52: 124-129, 1984.
16. Fagard, R. H. Impact of different sports and training on cardiac structure and function. Cardiol. Clin. 10: 241-256, 1992.
17. Fagard, R. H. Athlete's heart: a meta-analysis of the echocardiographic experience. Int. J. Sports Med. 17: S140-S144, 1996.
18. Freeman, A. R., and S. A. Levine. The clinical significance of the systolic murmur. A study of 1,000 consecutive "non-cardiac" cases. Ann. Intern. Med. 6: 1371-1385, 1933.
19. Gilbert, C. A., D. O. Nutter, J. M. Felner, J. V. Perkins, S. B. Heymsfield, and R. C. Schlant. Echocardiographic study of cardiac dimensions and function in the endurance-trained athlete. Am. J. Cardiol. 40: 528-533, 1977.
20. Grandjean, D., and B. M. Paragon. Nutrition of racing and working dogs. II. Determination of energy requirements and the nutritional impact of stress. Comp. Cont. Educ. Pract. Vet. 15: 45-57, 1993.
21. Grossman, W., D. Jones, and L. P. McLaurin. Wall stress and patterns of hypertrophy in the human left ventricle. J. Clin. Invest. 56: 56-64, 1975.
22. Herrmann, G. R. Experimental heart disease. I. Methods of dividing hearts; with sectional and proportional weights and ratios for 200 normal dogs' hearts. Am. Heart J. 1: 213-231, 1925.
23. Hoffmann, M. D., K. M. Kassay, A. I. Zeni, and P. S. Clifford. Does the amount of exercising muscle alter the aerobic demand of dynamic exercise? Eur. J. Appl. Physiol. 74: 541-547, 1996.
24. Huonker, M., D. Konig, and J. Keul. Assessment of left ventricular dimensions and functions in athletes and sedentary subjects at rest and during exercise using echocardiography, Doppler sonography and radionuclide ventriculography. Int. J. Sports Med. 17, Suppl. 3: S173-S179, 1996.
25. Huston, T. P., J. C. Puffer, and W. M. Rodney. The athletic heart syndrome. N. Engl. J. Med. 313: 24-32, 1985.
26. Karjalainen, J., M. Mantysaari, M. Viitasalo, and U. Kujala. Left ventricular mass, geometry, and filling in endurance athletes: association with exercise blood pressure. J. Appl. Physiol. 82: 531-537, 1997.
27. Lewis, J. F., P. Spirito, A. Pelliccia, and B. J. Maron. Usefulness of Doppler echocardiographic assessment of diastolic filling in distinguishing "athlete's heart" from hypertrophic cardiomyopathy. Br. Heart J. 68: 296-300, 1992.
28. Lombard, C. W. Normal values of the canine M-mode echocardiogram. Am. J. Vet. Res. 45: 2015-2018, 1984.
29. Lust, R. M., L. O. Lutherer, and M. W. Cooper. Applicability of echocardiography in volume determinations in experimental animals. J. Appl. Physiol. 56: 1670-1674, 1984.
30. Mackintosh, I. C., I. C. Dormehl, A. L. van Gelder, and M. du Plessis. Blood volume, heart rate, and left ventricular ejection fraction changes in dogs before and after exercise during endurance training. Am. J. Vet. Res. 44: 1960-1962, 1983.
31. Maron, B. J. Structural features of the athlete's heart as defined by echocardiography. J. Am. Coll. Cardiol. 7: 190-203, 1986.
32. Mashiro, I., R. R. Nelson, J. N. Cohn, and J. A. Franciosa. Ventricular dimensions measured noninvasively by echocardiography in the awake dog. J. Appl. Physiol. 42: 953-959, 1976.
33. McKeever, K. H., W. A. Schurg, and V. A. Convertino. Exercise training-induced hypervolemia in greyhounds: role of water intake and renal mechanisms. Am. J. Physiol. 248 (Renal Fluid Electrolyte Physiol. 17): R422-R425, 1985.
34. Missault, L., D. Duprez, L. Jordaens, M. de Buyzere, K. Bonny, L. Adang, and D. Clement. Cardiac anatomy and diastolic filling in professional road cyclists. Eur. J. Appl. Physiol. 66: 405-408, 1993.
35. Morganroth, J., B. J. Maron, W. L. Henry, and S. E. Epstein. Comparative left ventricular dimensions in trained athletes. Ann. Intern. Med. 82: 521-524, 1975.
36. Morrison, S. A., N. S. Moise, J. Scarlett, H. Mohammed, and A. E. Yeager. Effect of breed and body weight on echocardiographic values in four breeds of dogs of differing somatotype. J. Vet. Intern. Med. 6: 220-224, 1992.
37. Mumford, M., and R. Prakash. Electrocardiographic and echocardiographic characteristics of long-distance runners. Comparison of left ventricular function with age- and sex-matched controls. Am. J. Sports Med. 9: 23-27, 1981.
38. Oakley, C. M. The electrocardiogram in the highly trained athlete. Cardiol. Clin. 10: 295-302, 1992.
39. Oakley, G. D. G. The athletic heart. Cardiol. Clin. 5: 319-329, 1987.
40. O'Grady, M. R., J. D. Bonagura, J. D. Powers, and D. S. Herring. Quantitative cross-sectional echocardiography in the normal dog. Vet. Radiol. 27: 34-49, 1986.
41. Page, A., G. Edmunds, and R. B. Atwell. Echocardiographic values in the greyhound. Aust. Vet. J. 70: 361-364, 1993.
42. Pavlik, G., N. Bachl, W. Wollein, G. Langfy, and L. Prokop. Resting echocardiographic parameters after cessation of regular endurance training. Int. J. Sports Med. 7: 226-231, 1986.
43. Pelliccia, A. Outer limits of physiologic hypertrophy and relevance to the diagnosis of primary cardiac disease. Cardiol. Clin. 10: 267-279, 1992.
44. Pelliccia, A., B. J. Maron, A. Spataro, M. A. Proschan, and P. Spirito. The upper limit of physiologic cardiac hypertrophy in highly trained elite athletes. N. Engl. J. Med. 324: 295-301, 1991.
45. Perrault, H., and R. A. Turcotte. Exercise-induced cardiac hypertrophy. Fact or fallacy? Sports Med. 17: 288-308, 1994.
46. Riedhammer, H. H., W. Rafflenbeul, W. H. Weihe, and H. P. Krayenbuhl. Left ventricular contractile function in trained dogs with cardial hypertrophy. Basic Res. Cardiol. 71: 297-308, 1976.
47. Rippe, J. M., L. A. Pape, J. S. Albert, I. S. Ockene, J. A. Paraskos, P. Kotilainen, J. Ana, and W. Webster. Studies of systolic mechanics and diastolic behavior of the left ventricle in the trained racing greyhound. Basic Res. Cardiol. 77: 619-644, 1982.
48. Ritzer, T. F., A. A. Bove, and R. A. Carey. Left ventricular performance characteristics in trained and sedentary dogs. J. Appl. Physiol. 48: 130-138, 1980.
49. Roeske, W. R., R. A. O'Roarke, A. Klein, G. Leopold, and J. S. Karliner. Noninvasive evaluation of ventricular hypertrophy in professional athletes. Circulation 53: 286-292, 1976.
50. Sahn, D. J., A. DeMaria, J. Kisslo, and A. Weyman. Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation 58: 1072-1083, 1978.
51. Schaible, T. F., and J. Scheuer. Cardiac adaptations to chronic exercise. Prog. Cardiovasc. Dis. 27: 297-324, 1985.
52. Schiller, N. B., C. G. Skioldegrand, E. J. Schiller, C. C. Mavroudis, N. H. Silverman, S. H. Rahimtoola, and M. J. Lipton. Canine left ventricular mass estimation by two-dimensional echocardiography. Circulation 68: 210-216, 1983.
53. Schneider, H. P., R. C. Truex, and J. O. Knowles. Comparative observations of the hearts of mongrel and greyhound dogs. Anat. Rec. 149: 173-180, 1964.
54. Serra Grima, J. R., J. Doxandabaratz, and J. L. Ventura. The veteran athlete. An exercise testing electrocardiographic, thorax X-ray and echocardiographic study. J. Sports Med. 21: 122-129, 1981.
55. Shub, C., A. L. Klein, P. K. Zacariah, K. R. Bailey, and A. J. Tajik. Determination of left ventricular mass by echocardiography in a normal population: effect of age and sex in addition to body size. Mayo Clin. Proc. 69: 205-211, 1994.
56. Snyder, P. S., T. Sato, and C. E. Atkins. A comparison of echocardiographic indices of the nonracing, healthy greyhound to reference values from other breeds. Vet. Radiol. Ultrasound 36: 387-392, 1995.
57. Stack, R. S., J. E. Ramage, R. P. Bauman, J. C. Rembert, H. R. Phillips, and J. A. Kisslo. Validation of in vivo two-dimensional echocardiographic measurements using myocardial mass estimates in dogs. Am. Heart J. 113: 725-731, 1987.
58. Stahl, W. R. Organ weights of primates and other mammals. Science 150: 1039-1042, 1965.
59. Steel, J. D., R. I. Taylor, P. E. Davis, G. A. Stewart, and P. W. Salmon. Relationships between heart score, heart weight and body weight in greyhound dogs. Aust. Vet. J. 52: 561-564, 1976.
60. Steinhaus, A. H., L. A. Hoyt, and H. A. Rice. Studies in the physiology of exercise. X. The effects of running and swimming on the organ weights of growing dogs. Am. J. Physiol. 99: 512-520, 1932.
61. Stone, H. L. Cardiac function and exercise training in conscious dogs. J. Appl. Physiol. 42: 824-832, 1977.
62. Teichholz, L. E., T. Kreulen, M. V. Herman, and R. Gorlin. Problems in echocardiographic volume determinations: echocardiographic-angiocardiographic correlations in the presence or absence of asynergy. Am. J. Cardiol. 37: 7-11, 1976.
63. Thomas, W. P., C. E. Gaber, G. J. Jacobs, P. M. Kaplan, C. W. Lombard, N. S. Moise, and B. L. Moses. Recommendations for standards in transthoracic two-dimensional echocardiography in the dog and cat. J. Vet. Intern. Med. 7: 247-252, 1993.
64. Tipton, C. M., R. A. Carey, W. C. Eastin, and H. H. Erickson. A submaximal test for dogs: evaluation of effects of training, detraining, and cage confinement. J. Appl. Physiol. 37: 271-275, 1974.
65. Urhausen, A., T. Monz, and W. Kindermann. Sports-specific adaptation of left ventricular muscle mass in athlete's heart. I. An echocardiographic study with combined isometric and dynamic exercise trained athletes (male and female rowers). Int. J. Sports Med. 17: S145-S151, 1996.
66. Van Citters, R. L., and D. L. Franklin. Cardiovascular performance of Alaska sled dogs during exercise. Circ. Res. 24: 33-42, 1969.
67. Weyman, A. E. Principles and Practice of Echocardiography. Philadelphia, PA: Lea & Febiger, 1994.
68. Woodiwiss, A. J., and G. R. Norton. Exercise-induced cardiac hypertrophy is associated with an increased myocardial compliance. J. Appl. Physiol. 78: 1303-1311, 1995.
69. Wyatt, H. L., M. K. Heng, S. Meerbaum, J. D. Hestenes, J. M. Cobo, R. M. Davidson, and E. Corday. Cross-sectional echocardiography. I. Analysis of mathematic models for quantifying mass of the left ventricle in dogs. Circulation 60: 1104-1113, 1979.
70. Wyatt, H. L., and J. H. Mitchell. Influences of physical training on the heart of dogs. Circ. Res. 35: 883-889, 1974.
71. Zehender, M., T. Meinertz, J. Keul, and H. Just. ECG variants and cardiac arrhythmias in athletes: clinical relevance and prognostic importance. Am. Heart J. 119: 1378-1391, 1990.