Results of immunoscintigraphy using a cocktail of radiolabeled monoclonal antibodies in the detection of colorectal cancer

Annals of Surgical Oncology

Volumn 5, Issue 6, 1998, Pages 489-494

  Volpe, Carmine M ^a,c   Abdel Nabi, Hani H ^b   Kulaylat, Mahmoud N ^a   Doerr, Ralph J ^a,b  

^a UNIVERSITY AT BUFFALO   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c BUFFALO GENERAL HOSPITAL   (United States)

Author keywords

Cocktail immunoscintigraphy; Colorectal cancer; Detection

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; IMMUNOGLOBULIN G2B; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY B.72.3;

ADULT; AGED; ARTICLE; CANCER STAGING; CLINICAL ARTICLE; CLINICAL TRIAL; COLORECTAL CANCER; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOSCINTIGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; ISOTOPE LABELING; MALE; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

AGED; ANTIBODIES, MONOCLONAL; ANTIGENS, NEOPLASM; CARCINOEMBRYONIC ANTIGEN; COLORECTAL NEOPLASMS; FEMALE; GLYCOPROTEINS; HUMANS; INDIUM RADIOISOTOPES; MALE; MIDDLE AGED; OLIGOPEPTIDES; PENTETIC ACID; PROSPECTIVE STUDIES; RADIOIMMUNODETECTION; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TOMOGRAPHY, X-RAY COMPUTED;

EID: 0031667209     PISSN: 10689265     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02303640     Document Type: Article

References (23)

1. Landis SH, Murray T, Bolden S, Wingo PA. Cancer statistics, 1998. CA Cancer J Clin 1998;48:10.
2. Bertsch DJ, Burak WE, Young DC, Arnold MW, Martin EW. Radioimmunoguided surgery system improves survival for patients with recurrent colorectal cancer. Surgery 1995;118:634-9.
3. Swedish Rectal Cancer Trial. Improved survival with preoperative radiotherapy in resectable rectal cancer. N Engl J Med 1997;336: 980-7.
4. Moertel CG, Fleming TR, MacDonald JS, et al. Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma. N Engl J Med 1990;322:352-8.
5. 99mTc-IMMU-4 monoclonal antibody scan in colorectal cancer. A prospective study. Arch Surg 1992;127:1321-4.
6. Doerr RJ, Abdel-Nabi H, Merchant B. Indium 111 ZCE-025 immunoscintigraphy in occult recurrent colorectal cancer with elevated carcinoembryonic antigen level. Arch Surg 1990;125: 226-9.
7. Halpern SE, Dillman RO, Amox D, et al. Detection of occult tumor using indium 111-labeled anticarcinoembryonic antigen antibodies. Arch Surg 1992;127:1094-1100.
8. Doerr RJ, Abdel-Nabi H, Krag D, Mitchell E. Radiolabeled antibody imaging in the management of colorectal cancer. Ann Surg 1991;214:118-24.
9. Rodwell JD, Alvarez VL, Lee C, et al. Site-specific covalent modification of monoclonal antibodies: in vitro and in vivo evaluations. Proc Natl Acad Sci USA 1986;83:2632-6.
10. Simpson JF, Primus FJ, Schlom J. Complementation of expression of carcinoembryonic antigen and tumor associated glycoprotein-72 (TAG-72) in human colon adenocarcinomas. Int J Biol Markers 1991;6:83-90.
11. Pressman D, Day ED, Blau M. The use of paired labeling in the determination of tumor-localizing antibodies. Cancer Res 1957;17: 845-50.
12. Gold P, Freedman SO. Specific carcinoembryonic antigens of the human digestive system. J Exp Med 1965;122:467-81.
13. Kohler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 1975;256:495-7.
14. Block GE, Collier BD, Doerr RJ, Martin EW, McKearn TJ, Thurston MO. Symposium on the practical applications for immunoscintigraphy in the surgical management of colorectal cancer. Contemp Surg 1993;42:287-311.
15. Arnold MW, Schneebaum S, Berens A, Petty L, Mojzisik C, Hinkle, Martin EW. Intraoperative detection of colorectal cancer with radioimmunoguided surgery and CC49, a second-generation monoclonal antibody. Ann Surg 1992;216:627-32.
16. Schneebaum S, Papo J, Graif M, Baratz M, Baron J, Skornik Y. Radioimmunoguided surgery benefits for recurrent colorectal cancer. Ann Surg Oncol 1997;4:371-6.
17. Tagliabue E, Porro G, Barbanti P, et al. Improvement of tumor cell detection using a pool of monoclonal antibodies. Hybridoma 1986; 5:107-15.
18. Collier BD, Abdel-Nabi H, Doerr RJ, et al. Immunoscintigraphy performed with In-111-labeled CYT-103 in the management of colorectal cancer: comparison with CT. Radiology 1992;185:179-86.
19. Nabi H, Doerr RJ, Balu D, Farrell E, Evans N. Colorectal carcinoma imaging with IN-111 Mab C46.3-GYK-DTPA (CYT-372). Preliminary clinical results. Eur J Nucl Med 1993;20:874. Abstract.
20. Abdel-Nabi HH, Schwartz AN, Goldfogel G, Ortman-Nabi JA, Matsuoka DM, Unger MW, Wechter DG. Colorectal tumors: Scintigraphy with In-111 anti-CEA monoclonal antibody and correlation with surgical, histopathologic, and immunohistochemical findings. Radiology 1988;166:747-52.
21. Quinlan D, Davidson A, Gamponia E, Lindley J, Doshi H. Detection of tumor-associated glycoprotein-72 (TAG-72) in short-term and long-term surviving colon cancer patients using a first- and second-generation monoclonal antibody. Proc Am Assoc Cancer Res 1991;32:271.
22. Volpe CM, Rodriguez-Bigas M, Petrelli NJ. Wide perineal dissection and its effect on local recurrence following potentially curative abdominoperineal resection for rectal adenocarcinoma. Cancer Invest 1996;14:1-5.
23. Cohen AM, Minsky BD, Schilsky RL. Colon cancer. In: DeVita VT Jr, Hellman S, Rosenberg SA, eds. Cancer: Principles and Practice of Oncology. 4th ed. Philadelphia: JB Lippincott, 1993: 929-77.