The effect of interferon-γ and tumor necrosis factor-α on the expression of ICAM-1 and HLA-DR molecules on cells of a human germ cell neoplasm and their susceptibility to lysis by lymphokine-activated killer cells

Pathobiology

Volumn 66, Issue 5, 1998, Pages 205-208

  Eisenthal, Avi ^a   Marder, Oleg ^a   Maymon, Batya ^a   Misonzhnik, Faina ^a   Skornick, Yehuda ^a   Brazowski, Eli ^a   Czernobilsky, Bernard ^a   Walt, Heinrich ^b   Lifschitz Mercer, Beatriz ^a  

^a TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^b UNIVERSITÄTSSPITAL ZÜRICH   (Switzerland)

Author keywords

Cytokines; Cytotoxicity; Germ cell tumor, human; ICAM 1; LAK cells

Indexed keywords

CHROMIUM 51; GAMMA INTERFERON; HLA DR ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL SURFACE; CONTROLLED STUDY; CYTOLYSIS; GERM CELL TUMOR; HUMAN; HUMAN CELL; LYMPHOKINE ACTIVATED KILLER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0031666980     PISSN: 10152008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000028024     Document Type: Article

References (18)

1. Skakkebaek NE, Berthelsen JG: Carcinoma m situ of the testis and invasive growth of different types of germ cell tumors. A revised germ cell theory. Int J Androl 1981;4:26-34.
2. Mummery CL, Van Rooyen M, Crakce M, Van Raaij J, Van Zoelen EJ, Alitalo K: Fibroblast growth factor-mediated growth regulation and receptor expression in embryonal carcinoma and embryonic stem cells and human germ cell tumors. Biochem Biophys Res Commun 1993; 191:188-195.
3. Hofmann MC, Jeltsch W, Bregcher J, Walt H: Alkaline phosphatase isozymes in human testicular germ cell tumors, their precancerous stage, and three related cell lines. Cancer Res 1989;49:4696-4700.
4. Niederberger M, DeLozier-Blanchet CD, Hedinger CE, Walt H: Differences between subcutaneous and intraperitoneal forms of three human testicular teratocarcinomas in nude mice. Cancer 1988;61:1571-1578.
5. Roberts K, Lotze MT, Rosenberg SA: Separation and functional studies of the human lymphokine-activated killer cell. Cancer Res 1987; 47:4366-4371.
6. Piontek GE, Taniguchi K, Ljunggren HG, Gronberg A, Kiessling R, Klein G, Karre K: Yac-1 MHC class I variants reveal an association between decreased NK sensitivity and increased H-2 expression after interferon treatment or in vivo passage. J Immunol 1985;135: 4281-4288
7. Chong AS, Boussy IA, Jiang XL, Lamas M, Graf LH Jr:CD54/ICAM-I is a costimulator of NK cell-mediated cytotoxicity. Cell Immunol 1994;157:92-105.
8. Kondo S, Yin D, Takeuchi J, Morimura T, Miyataka DI, Nakatsu S, Oda Y, Kikuchi H: Tumor necrosis factor-alpha induces an increase in the susceptibility of human glioblastoma U87-MG cells to natural killer cell-mediated lysis. Br J Cancer 1994;69:627-632.
9. Watanabe Y, Morita M, Ikematsu N, Akaike T: Tumor necrosis factor alpha and interleukin-1 beta but not Interferon-gamma induce vascular cell adhesion molecule-1 expression on primary cultured murine hepatocytes. Biochem Biophys Res Commun 1995;209:335-342.
10. Norgauer J, Bartles F, Gohring U, Schopf E, Gebicke-Haerter P, Kownatzki E, Knitmann J: Expression of intracellular adhesion molecule-1 is regulated by the actin network in epidermoid carcinoma cells. Exp Cell Res 1995;219:15-20.
11. Walt H, Hedinger CE: Differentiation of human testicular embryonal carcinoma and teratocarcinoma grown in nude mice and soft agar cultures. Cell Differ 1984;15:81-86.
12. Eisenthal A, Skornick Y, Ron I, Zakuth V, Chaitchik S: Phenotypic and functional profile of peripheral blood mononuclear cells isolated from melanona patients undergoing combined immunotherapy and chemotherapy. Cancer Immunol Immunother 1993;37:367-372.
13. Abdel-Wahab ZA, Osanto S, Darrow TL, Barber JR, Vervaert CE, Gangavalli R, McCallister TJ, Seigler HF: Transduction of human melanoma cells with the gamma-interferon. Cancer Gene Ther 1993;1:171-179.
14. Paolieri F, Battifora M, Riccio AM, Pesce G, Canonica GW, Bagnasco M: Intercellular adhesion molecule-1 on cultured human epithelial cell lines: Influence of proinflammatory cytolanes. Allergy 1997;52:521-531.
15. Bornstem J, Lahat N, Kinarty A, Revel M, Abramovici H, Shapiro S: Interferon-β and γ, but not tumor necrosis factor-α, demonstrate immunoregulatory effects on carcinoma cell lines infected with human papilloma virus. Cancer 1997;79:924-934.
16. Pfizenmaier K, Scheurich P, Schluter C, Kronke M: Tumor necrosis factor enhances HLA-A,B,C and HLA-DR gene expression in human tumor cells. J Immunol 1987;138:975-980.
17. Kim JD, Lee JL, Park JH, Lee JM, Kim YH, Kim SJ: Induction of ICAM-1 and HLA-DR expression by IFN-gamma in malignant melanoma cell lines. Yonsei Med J 1995;36:15-25.
18. Grimm EA, Mazumder A, Zhang HZ, Rosenberg SA: Lymphokine-activated killer cell phenomenon: Lysis of natural killer resistant fresh solid tumor cells by interleukin-2 activated autologous human peripheral blood lymphocytes. J Exp Med 1982;155:1823-1841.