Effects of nicotine and mecamylamine microinjections into the nucleus accumbens on ethanol and sucrose self-administration

Alcoholism: Clinical and Experimental Research

Volumn 22, Issue 6, 1998, Pages 1190-1198

  Nadal, R ^a,b   Chappell, A M ^a   Samson, H H ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Acetylcholine; Alcohol; Dopamine; Mesolimbic; Reinforcement

Indexed keywords

ACETYLCHOLINE; ALCOHOL; DOPAMINE; MECAMYLAMINE; NICOTINE;

ALCOHOL CONSUMPTION; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRINKING BEHAVIOR; MALE; MICROINJECTION; NEUROMODULATION; NEUROPSYCHOLOGY; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; REINFORCEMENT;

ANIMALIA;

EID: 0031666575     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1998.tb03898.x     Document Type: Article

References (48)

1. Collins AC, Romm E, Selvaag S, Turner S, Marks MJ: A comparison of the effects of chronic nicotine infusion on tolerance to nicotine and cross-tolerance to ethanol in long- and short-sleep mice. J Pharmacol Exp Ther 266:1390-1397, 1993
2. Meliska CJ, Bartke A, McGlacken G, Jensen RA: Ethanol, nicotine, amphetamine, and aspartame consumption and preferences in C57BL/6 and DBA/2 mice. Pharmacol Biochem Behav 50:619-626, 1995
3. Hatchell PC, Collins AC: The influence of genotype and sex on behavioral sensitivity to nicotine in mice. Psychopharmacology 71:45-49, 1980
4. Gessa GL, Muntoni F, Collu M, Vargiu L, Mereu G: Low doses of ethanol activate dopaminergic neurons in the ventral tegmental area. Brain Res 348:201-203, 1985
5. Brodie MS, Shefner SA, Dunwiddie TV: Ethanol increases the firing rate of dopamine neurons of the rat ventral tegmental area in vitro. Brain Res 508:65-69, 1990
6. Di Chiara G, Imperato A: Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc Natl Acad Sci USA 85:5274-5278, 1988
7. Weiss F, Lorang MT, Bloom FE, Koob GF: Oral ethanol self-administration stimulates dopamine release in the rat nucleus accumbens: Genetic and motivational determinants. J Pharmacol Exp Ther 267:250-258, 1993
8. Hodge CW, Samson HH, Haraguchi M: Microinjections of dopamine agonists in the nucleus accumbens increase ethanol-reinforced responding. Pharmacol Biochem Behav 43:249-254, 1992
9. Hodge CW, Samson HH, Chappelle AM: Alcohol self-administration: Further examination of the role of dopamine receptors in the nucleus accumbens. Alcohol Clin Exp Res 21:1083-1091, 1997
10. Samson HH, Hodge CW, Tolliver GA, Haraguchi M: Effect of dopamine agonists and antagonists on ethanol-reinforced behavior: The involvement of the nucleus accumbens. Brain Res Bull 30:133-141, 1993
11. Mereu G, Yoon K-WP, Boi V, Gessa GL, Naes L, Westfall TC: Preferential stimulation of ventral tegmental area dopaminergic neurons by nicotine. Eur J Pharmacol 141:395-399, 1987
12. Nisell M, Nomikos GG, Hertel P, Panagis G, Svensson TH: Conditioned-independent sensitization of locomotor stimulation and mesocortical dopamine release following chronic nicotine treatment in the rat. Synapse 22:369-381, 1996
13. Imperato A, Mulas A, Di Chiara G: Nicotine preferentially stimulates dopamine release in the limbic system of freely moving rats. Eur J Pharmacol 132:337-338, 1986
14. Mifsud J-C, Hernández L, Hoebel BG: Nicotine infused into the nucleus accumbens increases synaptic dopamine as measured by in vivo microdialysis. Brain Res 478:365-367, 1989
15. Nisell M, Nomikos GG, Svensson TH: Systemic nicotine-induced dopamine release in the rat nucleus accumbens is regulated by nicotinic receptors in the ventral tegmental area. Synapse 16:36-44, 1994
16. Corrigall WA, Franklin KBJ, Coen KM, Clarke PBS. The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine. Psychopharmacology 107:285-289, 1992
17. Kita T, Okamoto M, Nakashima T: Nicotine-induced sensitization to ambulatory stimulant effect produced by daily administration into the ventral tegmental area and the nucleus accumbens in rats. Life Sci 50: 583-590, 1992
18. Leikola-Pelho T, Jackson DM: Preferential stimulation of locomotor activity by ventral tegmental microinjections of (-)-nicotine. Pharmacol Toxicol 70:50-52, 1992
19. Clarke PBS, Kumar R: Characterization of the locomotor stimulant action of nicotine in tolerant rats. Br J Pharmacol 80:587-594, 1983
20. Blomqvist O, Engel JA, Nissbrandt H, Söderpalm B: The mesolimbic dopamine-activating properties of ethanol are antagonized by mecamylamine. Eur J Pharmacol 249:207-213, 1993
21. Blomqvist O, Söderpalm B, Engel JA: Ethanol-induced locomotor activity: Involvement of central nicotinic acetylcholine receptors? Brain Res Bull 29:173-178, 1992
22. Katner SN, McBride WJ, Lumeng L, Li T-K, Murphy JM: Involvement of CNS cholinergic systems in alcohol drinking of P rats. Addict Biol 2:215-223, 1997
23. Blomqvist O, Ericson M, Johnson DH, Engel JA, Söderpalm B: Voluntary ethanol intake in the rat: Effects of nicotinic acetylcholine receptor blockade or subchronic nicotine treatment. Eur J Pharmacol 314:257-267, 1996
24. Potthoff AD, Ellison G, Nelson L: Ethanol intake increases during continuous administration of amphetamine and nicotine, but not several other drugs. Pharmacol Biochem Behav 18:489-493, 1983
25. Johnson DH, Blomqvist O, Engel JA, Söderpalm B: Suchronic intermittent nicotine treatment enhances ethanol-induced locomotor stimulation and dopamine turnover in mice. Behav Pharmacol 6:203-207, 1995
26. Nadal R, Samson HH: Operant ethanol self-administration after nicotine treatment and withdrawal. Submitted for publication, 1998
27. A agonist muscimol on self-administration of ethanol and sucrose. Pharmacol Biochem Behav 53:971-977, 1996
28. 10 dopamine neurons by gamma-aminobutyric acid agonists. J Pharmacol Exp Ther 253:858-866, 1990
29. Samson HH: Initiation of ethanol reinforcement using a sucrose-substitution procedure in food- and water-sated rats. Alcohol Clin Exp Res 10:436-442, 1986
30. Samson HH, Tolliver GA, Haraguchi M, Kalivas PW: Effects of d-amphetamine injected into the nucleus accumbens on ethanol reinforced behavior. Brain Res Bull 27:267-271, 1991
31. Samson HH, Hodge CW: Neurobehavioral regulation of ethanol intake, in Deitrich RA, Erwin VG (eds): Pharmacological Effects of Ethanol on the Nervous System. Boca Raton, CRC Press, 1996, p 203
32. Collins AC: The nicotinic cholinergic receptor as a potential site of ethanol action, in Deitrich RA, Erwin VG (eds): Pharmacological Effects of Ethanol on the Nervous System. Boca Raton, CRC Press, 1996, p 95
33. 3H]dopamine release from mouse striatal synaptosomes. J Neurochem 62:1390-1398, 1994
34. Levin DE, Briggs SJ, Christopher NC, Auman JT: Working memory performance and cholinergic effects in the ventral tegmental area and substantia nigra. Brain Res 657:165-170, 1994
35. Katner SN, McBride WJ, Lumeng L, Li T-K, Murphy JM: Effects of cholinergic agents on locomotor activity of P and NP rats. Alcohol Clin Exp Res, 20:1004-1010, 1996
36. Welzl H, Bättig K, Berz S: Acute effects of nicotine injection into the nucleus accumbens on locomotor activity in nicotine-naive and nicotine-tolerant rats. Pharmacol Biochem Behav 37:743-746, 1990
37. Ericson M, Blomqvist O, Engel JA, Söderpalm B: Ethanol activates the mesolimbic system via an indirect loop involving the ventral tegmental nicotinic acetylcholine receptors. Soc Neurosci 23:2399, 1997
38. Blomqvist O, Ericson M, Engel JA, Söderpalm B: Accumbal dopamine overflow after ethanol: Localization of the antagonizing effect of mecamylamine. Eur J Pharmacol 334:149-156, 1997
39. O'Dell TJ, Christensen BN: Mecamylamine is a selective non-competitive antagonist of N-methyl-D-aspartate- and aspartate-induced currents in horizontal cells dissociated from the catfish retina. Neurosci Let 94:93-96, 1988
40. Rassnikc S, Pulvirenti L, Koob GF: Oral ethanol self-administration in rats is reduced by the administration of dopamine and glutamate receptor antagonists into the nucleus accumbens. Psychopharmacology 109:92-98, 1992
41. Nagata K, Aistrup GL, Huang C-S, Marszalec W, Song J-H, Yeh JZ, Narahashi T: Potent modulation of neuronal nicotinic acetylcholine receptor-channel by ethanol. Neurosci Let 217:189-193, 1996
42. Nadal R, Prat G, Pallarés M, Hernández-Torres M, Ferré N: Effects of bromocriptine on self-administration of sweetened solutions in rats. Psychopharmacology 128:45-53, 1996
43. May T, Wolf U, Wolffgramm J: Striatal dopamine receptors and adenylyl cyclase activity in a rat model of alcohol addiction: Effects of ethanol and lisuride treatment. J Pharmacol Exp Ther 275:1195-1203, 1995
44. McBride WJ, Murphy JM, Lumeng L, Li T-K: Serotonin, dopamine and GABA involvement in alcohol drinking of selectively bred rats. Alcohol 7:199-205, 1990
45. Weiss F, Mitchiner M, Bloom FE, Koob GF: Free-choice responding for ethanol versus water in alcohol preferring (P) and unselected Wistar rats is differentially modified by naloxone, bromocriptine, and methysergide. Psychopharmacology 101:178-186, 1990
46. Linseman MA: Effects of dopaminergic agents on alcohol consumption by rats in a limited access paradigm. Psychopharmacology 100: 195-200, 1990
47. George SR, Fan T, Ng GYK, Jung SY, O'Dowd BF, Naranjo CA: Low endogenous dopamine function in brain predisposes to high alcohol preference and consumption: Reversal by increasing synaptic dopamine. J Pharmacol Exp Ther 273:373-379, 1995
48. Blomqvist O, Ericson M, Engel JA, Söderpalm B: Ethanol and nicotine: dose-dependent interactions in the regulation of locomotor activity and mesolimbic dopamine in rodents. Soc Neurosci 23:2400, 1997