Importance of a conserved TCR J α-encoded tyrosine for T cell recognition of an HLA B27/peptide complex

European Journal of Immunology

Volumn 28, Issue 9, 1998, Pages 2704-2713

  Bowness, Paul ^a   Allen, Rachel L ^a   Barclay, Douglas N ^a   Yvonne Jones, E ^b   McMichael, Andrew J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

HLA B27; TCR; Tetrameric MHC complex

Indexed keywords

HLA B27 ANTIGEN; T LYMPHOCYTE RECEPTOR; TYROSINE;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; ARTICLE; CONTROLLED STUDY; DEGRANULATION; DNA TRANSFECTION; GENETIC CONSERVATION; MAST CELL LEUKEMIA; NONHUMAN; PRIORITY JOURNAL; RAT; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; T LYMPHOCYTE; T LYMPHOCYTE RECEPTOR GENE;

AMINO ACID SEQUENCE; ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, VIRAL; COMPLEMENTARITY DETERMINING REGIONS; HLA-B27 ANTIGEN; HUMANS; IMMUNOGLOBULIN ALPHA-CHAINS; INFLUENZA A VIRUS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; RATS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA;

EID: 0031666385     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199809)28:09<2704::AID-IMMU2704>3.0.CO;2-B     Document Type: Article

References (28)

1. Davis, M. M. and Bjorkman, P. J., T cell antigen receptor genes and T cell recognition. Nature 1989. 334: 395-402.
2. Chothia, C., Boswell, D. R. and Lesk, A. M., The outline structure of the T-cell alpha beta receptor. EMBO J. 1988. 7: 3745-3755.
3. Engel, I., Ottenhoff, T. H. M. and Klausner, R. D., High-efficiency expression and solubilization of functional T cell antigen receptor heterodimers. Science 1992. 256: 1318-1321.
4. Jorgensen, J. L., Esser, U., Fazekas de St. Groth, B., Reay, P. A. and Davis, M. M., Mapping T-cell receptor-peptide contacts by variant peptide immunization of single-chain transgenics. Nature 1992. 355: 224-230.
5. Romero, P., Casanova, J. L., Cerottini, J. C., Maryanski, J. L. and Luescher, I. F., Differential T cell receptor photoaffinity labeling among H-2Kd restricted cytotoxic T lymphocyte clones specific for a photoreactive peptide derivative. Labeling of the alpha-chain correlates with J alpha segment usage. J. Exp. Med. 1993. 177: 1247-1256.
6. Garboczi, D. N., Ghosh, P., Utz, U., Fan, Q. R., Biddison, W. E. and Wiley, D. C., Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature 1996. 384: 134-141.
7. Ding, Y.-H., Smith, K. J., Garboczi, D. N., Utz, U., Biddison, W. E. and Wiley, D. C., Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/tax peptide complex using different TCR amino acids. Immunity 1998. 8: 403-411.
8. Bowness, P., Moss, P. A. H., Rowland-Jones, S. L., Bell, J. I. and McMichael, A. J., Conservation of T-Cell Receptor Usage by HLA B27-Restricted Influenza-Specific Cytotoxic T-Lymphocytes Suggests a General Pattern for Antigen-Specific Major Histocompatibility Complex Class-I-Restricted Responses. Eur. J. Immunol. 1993. 23: 1417-1421.
9. Koop, B. F., Rowen, L., Wang, K. et al., The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. Genomics 1994. 19: 478-493.
10. Callan, M. F., Reyburn, H. T., Bowness, P., Ottenhoff, T. H., Engel, I., Klausner, R. D., Bell, J. I. and McMichael, A. J., A method for producing monoclonal antibodies to human T-cell-receptor beta-chain variable regions. Proc. Natl. Acad. Sci. USA 1993. 90: 10454-10458.
11. Bowness, P., Allen, R. L. and McMichael, A. J., Identification of T cell receptor recognition residues for a viral peptide presented by HLA B27. Eur. J. Immunol. 1994. 24: 2357-2363.
12. Garcia, K. C., Degano, M., Stanfield, R. L., Brunmark, A., Jackson, M. R., Peterson, P. A., Teyton, L. and Wilson, I. A., An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex. Science 1996. 274: 209-219.
13. Madden, D. R., Gorga, J. C., Strominger, J. L. and Wiley, D. C., The structure of HLA B27 reveals nonamer self-peptides bound in an extended conformation. Nature 1991. 353: 321-325.
14. Madden, D. R., Gorga, J. C., Strominger, J. L. and Wiley, D. C., The three dimensional structure of HLA-B27 at 2.1 Å resolution suggests a general mechanism for tight peptide binding to MHC. Cell 1992. 70: 1035-1048.
15. Rabinowitz, J. D., Beeson, C., Lyons, D. S., Davis, M. M. and McConnell, H. M., Kinetic discrimination in T-cell activation. Proc. Natl. Acad. Sci. USA 1996. 93: 1401-1405.
16. Nalefski, E. A., Kasibhatla, S. and Rao, A., Functional analysis of the antigen binding site on the T cell receptor alpha chain. J. Exp. Med. 1992. 175: 1553-1563.
17. Chang, H. C., Smolyar, A., Spoerl, R., Witte, T., Yao, Y., Goyarts, E. C., Nathenson, S. G. and Reinherz, E. L., Topology of T cell receptor-peptide/class I MHC interaction defined by charge reversal complementation and functional analysis. J. Mol. Biol. 1997. 271: 278-293.
18. Garcia, K. G., Degano, M., Pease, L. R., Huang, M., Peterson, P. A., Teyton, L. and Wilson, I. A., Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen. Science 1998. 279: 1166-1173.
19. Moss, P. A. and Bell, J. I., Sequence analysis of the human αβ T-cell receptor CDR3 region. Immunogenetics 1995. 42: 10-18.
20. Callan, M. F. C., Reyburn, H. T., Bowness, P., Rowland, J. S., Bell, J. I. and McMichael, A. J., Selection of T cell receptor variable gene-encoded amino acids on the third binding site loop: A factor influencing variable chain selection in a T cell response. Eur. J. Immunol. 1995. 25: 1529-1534.
21. Barber, D. F., Lopez, D. and Lopez de Castro, J., T cell receptor diversity in alloreactive responses against HLA-B27 (B*2705) is limited by multiple-level restrictions in both alpha and beta chains. Eur. J. Immunol. 1995. 25: 2479-2485.
22. Viney, J. L., Prosser, H. M., Hewitt, C. R., Lamb, J. R. and Owen, M. J., Generation of monoclonal antibodies against a human T cell receptor beta chain expressed in transgenic mice. Hybridoma 1992. 11: 701-713.
23. Altman, J. D., Moss, P., Goulder, P., Barouch, D. H., McHeyzer, W. M., Bell, J. I., McMichael, A. J. and Davis, M. M., Phenotypic analysis of antigen-specific T lymphocytes. Science 1996. 274: 94-96.
24. Stuart, D. L., Levine, M., Muirhead, H. and Stammers, D. K., The crystal structure of cat pyruvate kinase at a resolution of 2.6 A. J. Mol. Biol. 1979. 134: 109-142.
25. Jones, T. A., Zou, J. Y., Cowan, S. and Kjeldgaard, M., Improved methods for building protein models in electron density maps and the location of errors in these models. Appl. Crystallogr. 1991. A47: 110-119.
26. Kraulis, P. J., MOLSCRIPT: a program to produce both detailed and schematic plots of protein structure. J. Appl. Crystallogr. 1991. 24: 946-950.
27. Esnouf, R. M., An extensively modified version of MolScript that includes greatly enhanced colouring capabilities. J. Mol. Graphics 1997. 15: 133-138.
28. Merritt, E. A. and Murphy, M. E. P., Raster3D version 2.0. A program for photorealistic molecular graphics. Acta Crystallogr. 1994. D50: 869-873.