HPV 16 infection and progression of cervical intra-epithelial neoplasia: Analysis of HLA polymorphism and HPV 16 E6 sequence variants

International Journal of Cancer

Volumn 78, Issue 2, 1998, Pages 166-171

  Bontkes, Hetty J ^a   Van Duin, Mark ^a   De Gruijl, Tanja D ^a   Duggan Keen, Maggie F ^c   Walboomers, Jan M M ^a   Strukart, Marij J ^a   Verheijen, René H M ^a   Helmerhorst, Theo J M ^b   Meijer, Chris J L M ^a   Scheper, Rik J ^a   Adam Stevens, F R ^c,d   Dyer, Philip A ^d   Sinnott, Paul ^d   Stern, Peter L ^c  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c CHRISTIE HOSPITAL   (United Kingdom)

^d ST MARY S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER SUSCEPTIBILITY; CONDYLOMA; DISEASE ASSOCIATION; DISEASE COURSE; FEMALE; GENE SEQUENCE; GENETIC POLYMORPHISM; HLA SYSTEM; HUMAN; IMMUNOPHENOTYPING; MAJOR CLINICAL STUDY; PAPANICOLAOU TEST; PRIORITY JOURNAL; UTERINE CERVIX CARCINOMA IN SITU; VIRUS GENE; WART VIRUS;

ADULT; ALLELES; CERVICAL INTRAEPITHELIAL NEOPLASIA; DISEASE PROGRESSION; FEMALE; GENOTYPE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; MIDDLE AGED; ONCOGENE PROTEINS, VIRAL; OPEN READING FRAMES; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; POLYMORPHISM, GENETIC; PROSPECTIVE STUDIES; REPRESSOR PROTEINS; TUMOR VIRUS INFECTIONS; UTERINE CERVICAL NEOPLASMS; VARIATION (GENETICS);

EID: 0031665699     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19981005)78:2<166::AID-IJC8>3.0.CO;2-X     Document Type: Article

References (21)

1. APPLE, R.J., BECKER, T.M., WHEELER, C.M. and ERLICH, H.A., Comparison of human leukocyte antigen DR-DQ disease associations found with cervical dysplasia and invasive cervical carcinoma. J. nat. Cancer Inst., 87, 427-136 (1995).
2. APPLE, R.J., ERLICH, H.A., KLITZ, W., MANOS, M.M., BECKER, T.M. and WHEELER, C.M., HLA DR-DQ associations with cervical carcinoma show papillomavirus-type specificity. Nature (Genet.), 6, 157-162 (1994).
3. BONTKES, H.J., WALBOOMERS, J.M.M., MEIJER, C.J.L.M., HELMERHORST, T.J.M. and STERN, P.L., Specific HLA class I down-regulation is an early event in cervical dysplasia associated with clinical progression. Lancet, 351, 187-188 (1998).
4. DE RODA HUSMAN, A.M., WALBOOMERS, J.M.M., VAN DEN BRULE, A.J.C., MEIJER, C.J.L.M. and SNIJDERS, P.J.F., The use of general primers GP5 and GP6 elongated at their 3′ ends with adjacent highly conserved sequences improves human papillomavirus detection by PCR. J. gen. Virol., 76, 1057-1062 (1995).
5. DUGGAN-KEEN, M.F., KEATING, P.J., STEVENS, F.R.A., SINNOTT, P., SNIJDERS, P.J.F., WALBOOMERS, J.M.M., DAVIDSON, S., HUNTER, R.D., DYER, P.A. and STERN, P.L., Immunogenetic factors in HPV-associated cervical cancer: influence on disease progression. Europ. J. Immunogenet., 23, 275-284 (1996).
6. KEATING. P.J., CROMME, F.V., DUGGAN-KEEN, M., SNLIJDERS, P.J.F., WALBOOMERS, J.M.M., HUNTER, R.D., DYER, P.A. and STERN, P.L., Frequency of down regulation of individual HLA-A and -B alleles in cervical carcinomas in relation to TAP-1 expression. Brit. J. Cancer, 72, 405-411 (1995).
7. LONDESBOROUGH, P., Ho, L., TERRY, G., CUZICK, J., WHEELER, C. and SINGER, A., Human papillomavirus genotype as a predictor of persistence and development of high-grade lesions in women with minor cervical abnormalities. Int. J. Cancer, 69, 364-368 (1996).
8. MELKERT, P.W., HOPMAN, E., VAN DEN BRULE, A.J., RISSE, E.K., VAN DIEST, P.J., BLEKER, O.P., HELMERHORST, T., SCHIPPER, M.E., MEIJER, C.J.L.M. and WALBOOMERS, J.M.M., Prevalence of HPV in cytomorphologically normal cervical smears, as determined by the polymerase chain reaction, is age-dependent. Int. J. Cancer, 53, 919-923 (1993).
9. MEYERS, G., BERNARD, H.U., DELIUS, H., FAVRE, M., ICENOGLE, J., VAN RANST, M. and WHEELER, C., Human papillomaviruses. A compilation and analysis of nucleic acid and amino acid sequences, Los Alamos National Laboratory, Los Alamos, NM (1995).
10. ODUNSI K., TERRY, G., Ho, L., BELL, J., CUZICK, J. and GANESAN, T.S., Susceptibility to human papillomavirus-associated cervical epithelial neoplasia is determined by specific DR-DQ alleles. Int. J. Cancer, 67, 595-602 (1996).
11. REMMINK, A.J., WALBOOMERS, J.M.M., HELMERHORST, T.J.M., VOORHORST, F.J., ROZENDAAL, L., RISSE, E.K.J., MEIJER, C.J.L.M. and KENEMANS, P., The presence of persistent high-risk HPV genotypes in dysplastic cervical lesions is associated with progressive disease: natural history up to 36 months. Int. J. Cancer, 61, 306-311 (1995).
12. SASTRE-GARAU, X., LOSTE, M.N., VINCENT-SALOMON, A., FAVRE, M., MOURET, E., DE LA ROCHEFORDIÉRE, A., DURAND, J.C., TARTOUR, E., LEPAGE, V. and CHARRON, D., Decreased frequency of HLA-DRB1*13 alleles in French women with HPV-positive carcinoma of the cervix. Int. J. Cancer, 69, 159-164 (1996).
13. SCHAFER, A., FRIEMANN, W., MIELKE, M., SCHWATLANDER, B. and KOCH, M.A., The increased frequency of cervical dysplasia in women infected with the human immunodeficiency virus is related to the degree of immunosuppression. Amer. J. Obstet. Gynaecol., 164, 593-599 (1991).
14. SCHIPPER, R.F., SCHREUDER, G.M.T., D'AMARO, J. and OUDSHOORN, M., HLA gene and haplotype frequencies in Dutch blood donors. Tissue Antigens, 48, 562-574 (1996).
15. STERN, P.L., Immunity' to human papillomavirus-associated cervical neoplasia. Adv. Cancer Res., 69, 175-211 (1996).
16. SYRJÄNEN, K., NURMI, T., MANTYJARVI, R., ILONEN, J., SYRJÄNEN, S., SURCEL, H.M., YLISKOSKI, M., VAYRYNEN, M., CHANG, F. and SAARIKOSKI, S., HLA types in women with cervical human papillomavirus (HPV) lesions prospectively followed up for 10 years. Cytopathology, 7, 99-107 (1996).
17. TERRY, G., Ho, L. and CUZICK, J., Analysis of E2 amino acid variants of human papillomavirus types 16 and 18 and their associations with lesion grade and HLA-DR/DQ type. Int. J. Cancer, 73, 651-655 (1997).
18. WANK, R. and THOMSSEN, C., High risk of squamous cell carcinoma of the cervix for women with HLA-DQw3. Nature, 352, 723-725 (1991).
19. XI, L.F., KOUTSKY, L.A., GALLOWAY, D.A., KUYPERS, J., HUGHES, J.P., WHEELER, C.M., HOLMES, K.K. and KIVIAT, N.B., Genomic variation of human papillomavirus type 16 and risk for high grade cervical intraepithelial neoplasia. J. nat. Cancer Inst., 89, 796-802 (1997).
20. YAMADA, T., MANOS, M.M., PETO, J., GREER, C.E., MUNOZ, N., BOSCH, F.X. and WHEELER, C.M., Human papillomavirus type 16 sequence variation in cervical cancers: a worldwide perspective. J. Virol., 71, 2463-2472 (1997).
21. ZUR HAUSEN, H., Molecular pathogenesis of cancer of the cervix and its causation by specific human papillomavirus types. In: H. zur Hausen (ed.), Human pathogenic papillomaviruses, pp. 131-156, Springer-Verlag, New York (1994).