Characterization of an anti-RNA recombinant autoantibody fragment (scFv) isolated from a phage display library and detailed analysis of its binding site on U1 snRNA

RNA

Volumn 4, Issue 9, 1998, Pages 1124-1133

  Teunissen, S W M ^a   Stassen, M H W ^a   Pruijn, G J M ^a   Van Venrooij, W J ^a   Hoet, R M A ^a,b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Footprinting; Phage display; RNA antibody complex; Single chain variable fragment; U1 snRNA

Indexed keywords

RIBONUCLEASE A; RNA ANTIBODY; SMALL NUCLEAR RNA;

ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; HUMAN; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; PHAGE DISPLAY; PRIORITY JOURNAL; RNA ANALYSIS; RNA BINDING; RNA SPLICING; RNA STRUCTURE; SEQUENCE ANALYSIS; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; AUTOANTIBODIES; BACTERIOPHAGES; BASE SEQUENCE; BINDING SITES; GENE LIBRARY; HUMANS; IMMUNOGLOBULIN FRAGMENTS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; RNA, SMALL NUCLEAR;

EID: 0031664959     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838298980633     Document Type: Article

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