Lack of efficacy of propofol in the treatment of early postoperative nausea and vomiting

Anaesthesia and Intensive Care

Volumn 26, Issue 4, 1998, Pages 366-370

  Harper, I ^a   Della Marta, E ^a,b   Owen, H ^a   Plummer, J ^a   Ilsley, A ^a  

^a FLINDERS MEDICAL CENTRE   (Australia)

^b Department of Nursing ^*

Author keywords

Anaesthesia, complications: nausea, vomiting, postoperative; Anaesthetics,intravenous: propofol; Antiemetics

Indexed keywords

ANESTHETIC AGENT; ANTIEMETIC AGENT; DROPERIDOL; INTRALIPID; PROPOFOL;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; GYNECOLOGIC SURGERY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LAPAROSCOPIC SURGERY; NAUSEA; RANDOMIZED CONTROLLED TRIAL; SEDATION; TREATMENT FAILURE; VOMITING;

EID: 0031664866     PISSN: 0310057X     EISSN: None     Source Type: Journal    
DOI: 10.1177/0310057x9802600404     Document Type: Article

References (19)

1. Watcha MF, White PF, Postoperative nausea and vomiting. Its etiology, treatment and prevention. Anesthesiology 1992; 77:162-184.
2. Haigh CG, Kaplan LA, Durham JM, Dupeyron JP, Harmer M, Kenny GN. Nausea and vomiting after gynaecological surgery: a meta-analysis of factors affecting their incidence. Br J Anaesth 1993; 71:517-522.
3. McCollum JSC, Milligan KR, Dundee JW. The antiemetic action of propofol. Anaesthesia 1988; 43:239-240.
4. Scher CS, Amar D, McDowall H, Barst SM. Use of propofol for the prevention of chemotherapy-induced nausea and emesis in oncology patients. Can J Anaesth 1992; 39:170-172.
5. Borgeat A, Wilder-Smith OHG, Saiah M, Rifat K. Subhypnotic doses of propofol possess direct antiemetic properties. Anesth Analg 1992; 74:539-541.
6. Lacroix G, Lessard MR, Trépanier CA. Treatment of postoperative nausea and vomiting: comparison of propofol, droperidol and metoclopramide. Can J Anaesth 1996; 43:115-120.
7. Montgomery JE, Sutherland CJ, Kestin IG, Sneyd JR. Infusions of suhhypnotic doses of propofol for the prevention of postoperative nausea and vomiting. Anaesthesia 1996; 51:554-557.
8. Meddis R. Statistics using ranks. A unified approach. Oxford: Basil Blackwell Publisher Ltd, 1984; 187-192.
9. Plummer JL, Owen H, Ilsley AH, Inglis S. Morphine patient-controlled analgesia is superior to meperidine patient-controlled analgesia for postoperative pain. Anesth Analg 1997; 84:794-799.
10. Lehmann EL. Nonparametrics. Statistical methods based on ranks. New York: McGraw-Hill 1975; 91-95.
11. Campbell NN, Thomas AD. Does propofol have an anti-emetic effect? A prospective study of the anti-emetic effect of propofol following laparoscopy. Anaesth Intensive Care 1991; 19:385-387.
12. Paxton LD, McKay AC, Mirakhur RK. Prevention of nausea and vomiting after day case gynaecological laparoscopy. A comparison of ondansetron, droperidol, metoclopramide and placebo. Anaesthesia 1995: 50:403-406.
13. Tramer M, Moore A, McQuay H. Omitting nitrous oxide in general anaesthesia: meta-analysis of intraoperative awareness and postoperative emesis in randomized controlled trials. Br J Anaesth 1996; 76:186-193.
14. Östman PL, Faure E, Glosten B, Kemen M, Robert MK, Bedwell S. Is the antiemetic effect of the emulsion formulation of propofol due to the lipid emulsion? Anesth Analg 1990; 71:536-540.
15. Torn K, Tuominen M, Tarkkila P, Lindgren L. Effects of subhypnotic doses of propofol on the side effects of intrathecal morphine. Br J Anaesth 1994; 73:411-412.
16. Schulman SR, Rockett CB, Canada AT, Glass PSA. Long-term propofol infusion for refractory postoperative nausea: A case report with quantitative propofol analysis. Anesth Analg 1995; 80:636-637.
17. Ewalenko P, Janny S, Dejonckheere M, Andry G, Wyns C. Antiemetic effect of subhypnotic doses of propofol after thyroidectomy. Br J Anaesth 1996; 77:463-467.
18. Scuderi PE, D'Angelo R, Harris L, Mims GR, Weeks DB, James RL. Small-dose propofol by continuous infusion does not prevent postoperative vomiting in females undergoing outpatient laparoscopy. Anesth Analg 1997: 84:71-75.
19. Zestos MM, Carr AS, McAuliffe G, Smith HS, Sikich N, Lerman J. Subhypnotic propofol does not treat postoperative vomiting in children after adenotonsillectomy. Can J Anaesth 1997; 44:401-404.