Methotrexate effects on trophoblast and the corpus luteum in early pregnancy

American Journal of Obstetrics and Gynecology

Volumn 179, Issue 3 I, 1998, Pages 604-609

  Creinin, M D ^a   Stewart Akers, A M ^a   DeLoia, J A ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

17 hydroxyprogesterone; Abortion; Methotrexate; Misoprostol; Progesterone; Serum human chorionic gonadotropin

Indexed keywords

CHORIONIC GONADOTROPIN BETA SUBUNIT; HYDROXYPROGESTERONE; METHOTREXATE; MISOPROSTOL; PROGESTERONE;

ADULT; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CORPUS LUTEUM; DRUG MECHANISM; FEMALE; FIRST TRIMESTER PREGNANCY; GESTATIONAL AGE; HORMONE BLOOD LEVEL; HUMAN; INDUCED ABORTION; PATIENT SELECTION; PRIORITY JOURNAL; TROPHOBLAST;

EID: 0031664658     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9378(98)70052-3     Document Type: Article

References (17)

1. MD Creinin E Vittinghoff L Keder PD Darney G Tiller Methotrexate and misoprostol for early abortion: a multicenter trial, I: safety and efficacy Contraception 53 1996 321 327
2. MD Creinin E Vittinghoff Methotrexate anal misoprostol versus misoprostol alone for early abortion: a randomized controlled trial JAMA 272 1994 1190 1195
3. MD Creinin E Vittinghoff S Galbraith C Klaisle A randomized trial comparing misoprostol 3 and 7 days following methotrexate for early abortion Am J Obstet Gynecol 1995 1578 1584
4. MD Creinin M Krohn Methotrexate pharmacokinetics and effects in women receiving methotrexate 50 mg and 60 mg per square meter for early abortion Am J Obstet Gynecol 177 1997 1444 1449
5. C Floridon O Nielsen C Byrjalsen B Hølund G Kerndrup SG Thomsen Ectopic pregnancy: histopathology and assessment of cell proliferation with and without methotrexate treatment Fertil Steril 65 1996 730 738
6. D Schafer J-P Pfuhl R Baumann S Neubert H-G Bender H Naujoks Trophoblast tissue culture of human intrauterine and ectopic pregnancies and treatment with methotrexate Hum Reprod 7 1992 311 319
7. MD Creinin PD Darney Methotrexate and misoprostol for early abortion Contraception 48 1993 339 348
8. MD Creinin Methotrexate for abortion at ≤42 days gestation Contraception 48 1993 519 525
9. E Radwanska J Frankenberg EI Allen Plasma progesterone levels in normal and abnormal early human pregnancy Fertil Steril 30 1978 398 402
10. ST Nakajima T McAuleffe M Gibson The 24-hour pattern of the levels of serum progesterone and immunoreactive human chorionic gonadotropin in normal early pregnancy J Clin Endocrinol Metab 71 1990 345 353
11. TR Yeko MJ Gorrill LH Hughes IA Rodi JE Buster MV Sauer Timely diagnosis of early ectopic pregnancy using a single blood progesterone measurement Fertil Steril 48 1987 1048 1050
12. CJ Hubinont C Thomas JF Schwers Luteal function in ectopic pregnancy Am J Obstet Gynecol 156 1987 669 674
13. TG Stovall FW Ling BJ Cope JE Buster Preventing ruptured ectopic pregnancy with a single serum progesterone Am J Obstet Gynecol 160 1989 1425 1431
14. RH Buck SM Joubert RJ Norman Serum progesterone in the diagnosis of ectopic pregnancy: a valuable diagnostic test? Fertil Steril 50 1988 752 755
15. S Daya Human chorionic gonadotropin increase in normal early pregnancy Am J Obstet Gynecol 156 1987 286 290
16. D Tulchinsky CJ Hobel E Yeager JR Marshall Plasma estrone, estradiol, estriol, progesterone, and 17-hydroxyprogesterone in human pregnancy, I: normal pregnancy Am J Obstet Gynecol 112 1972 1095 1100
17. WL Hermann AM Schindler R Wyss P Bischof Effects of the antiprogesterone RU 486 in early pregnancy and during the menstrual cycle EE Baulieu SJ Segal The antipro-gestin RU 486 and human fertility control 1985 Plenum Press New York 179 198