The effect of 12-alkoxy modification on the in vitro antileukaemic activity of N-methyl 2,3,8,9-tetramethoxybenzo[c]phenanthridinium salts

Anti-Cancer Drug Design

Volumn 13, Issue 7, 1998, Pages 797-813

  Mackay, Simon P ^e   Comoe, Leopold ^a   Desoize, Bernard ^b   Duval, Olivier ^c   Jardillier, Jean Claude ^b   Waigh, Roger D ^d  

^a Faculte de Pharmacie   (Côte d’Ivoire)

^b INSTITUT JEAN GODINOT   (France)

^c UFR de Pharmacie   (France)

^d UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^e UNIVERSITY OF SUNDERLAND   (United Kingdom)

Author keywords

Antileukaemic; Benzo c phenanthridine; DNA binding; Structure activity relationship; Synthesis

Indexed keywords

ANTILEUKEMIC AGENT; BENZO[C]PHENANTHRIDINE DERIVATIVE; DNA;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL STRAIN K 562; CONTROLLED STUDY; DRUG DNA BINDING; DRUG POTENCY; DRUG STRUCTURE; LEUKEMIA CELL; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; HUMANS; K562 CELLS; LEUKEMIA; LEUKEMIA P388; PHENANTHRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA;

EID: 0031663781     PISSN: 02669536     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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