Plasma and muscle polyamine levels in aerobically exercised rats treated with salbutamol

Journal of Pharmacy and Pharmacology

Volumn 50, Issue 9, 1998, Pages 1059-1064

  Cepero, M ^a   Cubria J C ^a   Reguera, R ^a   Balana Fouce R ^a   Ordonez C ^a   Ordonez D ^a   Escudero, D O ^b  

^a Departamento de Fisiologia Morfologia e Patolgia   (Spain)

^b Campus de Vegazana   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

POLYAMINE; PROPRANOLOL; PUTRESCINE; SALBUTAMOL; SPERMIDINE; SPERMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; EXERCISE; HEART VENTRICLE HYPERTROPHY; HEART WEIGHT; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MUSCLE HYPERTROPHY; MUSCLE LEVEL; MUSCLE MASS; NONHUMAN; RAT;

EID: 0031663625     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.1998.tb06922.x     Document Type: Article

References (32)

1. Bardocz, S., Brown, D. S., Grant, G., Pusztai, A., Stewart, J. C., Palmer, R. M. (1992) Effect of the beta-adrenoceptor agonist clenbuterol and phytohaemaglutinin on growth, protein synthesis and polyamine metabolism of tissues of the rat. Br. J. Pharmacol. 106: 476-482
2. Bartolome, J. W., Huguenard, J., Slotkin, T. A. (1980a) Role of ornithine decarboxylase in cardiac growth and hypertrophy. Science 210: 793-794
3. Bartolome, J. W., Trepanier, P. A., Chaidt, E. A., Slotkin, T. A. (1980b) Role of polyamines in isoproterenol-cardiac induced hypertrophy: effect of α-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase. Mol. Cell. Cardiol. 14: 461-466
4. Bates, P. C., Pell, J. M. (1990) Action and interaction of growth hormone and the beta-agonist elenbuterol on growth, body composition and protein turnover in dwarf mice. Br. J. Nutr. 65: 115-129
5. Benson, D. W., Foley-Nelson, T., Chance, W. T., Zhang, F., James, J. H., Fischer, J. E. (1991) Decreased myofibrillar protein breakdown following treatment with clenbuterol. J. Surg. Res. 50: 1-5
6. Caldarera, C. M., Orlandini, G., Casti, A., Moruzzi, G. (1974) Polyamines and nucleic acid metabolism in myocardial hypertrophy of overloaded heart. J. Mol. Cell. Cardiol. 6: 95-104
7. Carter, W. J., Lynch, M. E. (1994) Comparison of the effects of salbutamol and elenbuterol on skeletal muscle mass and carcass composition in senescent rats. Metabolism 43: 1119-1125
8. Carter, W. J., Dang, A. Q., Faas, F. H., Lynch, M. E. (1991) Effects of elenbuterol on skeletal muscle mass, body composition and recovery from surgical stress in senescent rats. Metabolism 40: 855-860
9. Cubría, J. C., Balaña-Fouce, R., Reguera, R., Ordóñez, D. (1998a) Early alterations of polyamine metabolism induced after acute administration of elenbuterol in mouse heart. Life Sci. In press
10. Cubría, J. C., Reguera, R. M., Balaña-Fouce, R., Ordóñez, C., Ordóñez, D. (1998b) Mouse heart hypertrophy induced by subacute administration of elenbuterol. J. Pharm. Pharmacol. 50: 91-96
11. Escribano, M. I., Merodio, C. (1994) The relevance of polyamine levels in cherimoya (Annona cherimola Mill) fruit ripening. J. Plant Physiol. 143: 207-212
12. Fan, C. H., Koenig, H. (1988) The role of polyamines in β-adrenergic stimulation of calcium influx and membrane transport in rat heart. J. MoI. Cell. Cardiol. 20: 789-799
13. Inman, M. D., O Byrne, P. M. (1996) The effect of regular inhaled albuterol on exercise-induced bronchoconstriction. Am. J. Respir. Crit. Care. Med. 153: 65-69
14. 2+ fluxes, endocytosis, hexose transport, and amino acid transport in mouse kidney cortex is mediated by polyamine synthesis. Proc. Natl Acad. Sci. USA 80: 7210-7214
15. i and membrane transport in rat heart myocytes. Biochem. Biophys. Res. Commun. 153: 1179-1185
16. Libretto, S. E. (1994) A review of the toxicology of salbutamol (albuterol). Arch. Toxicol. 68: 213-216
17. Maltin, C. A., Delday, M. I., May, S. M., Smith, F. E., Lobley, G. E., Reeds, P. J. (1987) The effect of the anabolic agent clenbuterol on overloaded rat skeletal muscle. Biosci. Rep. 7: 143-150
18. Maltin, C. A., Hay, S. M., Delday, M. I., Lobley, G. E., Reeds, P. J. (1989) The action of the β-agonist clenbuterol on protein metabolism in enervated and denervated phasic muscles. Biochem. J. 261: 965-971
19. Maltin, C. A., Jones, P., Mantle, D. (1993) Effect of protease inhibitors and clenbuterol on the in vitro degradation of dysthrophin by endogenous proteases in human skeletal muscle. Biosci. Rep. 13: 159-167
20. McCann, P. P., Pegg, A. E. (1992) Ornithine decarboxylase as an enzyme target for therapy. Pharmacol. Ther. 54: 195-215
21. Pegg, A. E. (1988) Polyamine metabolism and its importance in neoplastic growth and as target for chemotherapy. Cancer Res. 48: 759-774
22. Pegg, A. E., Hibasami, H. (1980) Polyamine metabolism during cardiac hypertrophy. Am. J. Physiol. 239: E272-E278
23. Price, A. H., Clissold, S. P. (1989) Salbutamol in 1980s. A reappraisal of its clinical efficacy. Drugs 38: 77-122
24. Reeds, P. J., Hay, S. M., Dorward, P. M., Palmer, R. M. (1986) Stimulation of muscle growth by clenbuterol: lack of effect on protein muscle biosynthesis. Br. J. Nutr. 60: 85-341
25. Rehfeldt, C., Weikard, R., Reichel, K. (1994) The effect of the beta-adrenergic agonist clenbuterol on the growth of skeletal muscles of rats. Arch. Tierenahr. 45: 333-344
26. Slotkin, T. A., Whitmore, W. L., Orband-Miller, L., Queen, K. L., Haim, K. (1987) Beta-adrenergic control of macromolecule synthesis in neonatal rat heart, kidney and lung: relationship to sympathetic neuronal development. J. Pharmacol. Exp. Ther. 243: 101-109
27. Stadel, J. M., Strulovici, B., Nambi, P., Lavin, T. N., Briggs, M. M., Caron, M. G., Lefkowitz, R. J. (1983) Desensitization of the β-adrenergic receptor of frog erythrocytes recovery and characterization of the down-regulated receptors in sequestered vesicles. J. Biol. Chem. 258: 3032-3038
28. Tipnis, U. R., Steiner, A. L., Skiera, C., Haddox, M. K. (1989) Immunolocalization of ornithine decarboxylase in rat heart atria. J. Mol. Cell. Cardiol. 21: 743-750
29. Willis, W. T., Dallman, P. R., Brooks, G. A. (1988) Physiological and biochemical correlates of increasing work in trained iron-deficient rats. J. Appl. Physiol. 65: 256-263
30. Yang, Y. T., McElligott, M. A. (1989) Multiple actions of beta-adrenergic agonist on skeletal muscle and adipose tissue. Biochem. J. 261: 1-10
31. Zeman, R. J., Ludemann, R., Etlinger, J. D. (1987) Clenbuterol, a beta 2-agonist, retards atrophy in denervated muscles. Am. J. Physiol. 252: E152-E155
32. 2-agonist retards wasting and loss of contractility in irradiated dystrophic mdx muscle. Am. J. Physiol. 267: C865-C867