Novel steroid-linked conjugates of 17β-[N-[N'-(2-chloroethyl)-N'-nitroso]carbamoyl]amino acids and their antineoplastic activity against Noble Nb prostate carcinoma model in rats

Anti-Cancer Drug Design

Volumn 13, Issue 7, 1998, Pages 815-824

  Tang, W ^b   Schneider, M R ^a   Eisenbrand, G ^b  

^a BAYER PHARMA AG   (Germany)

^b Rheinland Pfälzische Technische Universität Kaiserslautern Landau   (Germany)

Author keywords

Antineoplastic; Drug targeting; N nitrosourea; Prostate carcinoma; Steroid linked conjugate

Indexed keywords

17BETA [N [N' (2 CHLOROETHYL) N' NITROSO]CARBAMOYL]ALANYL 19 NORTESTOSTERONE; 17BETA [N [N' (2 CHLOROETHYL) N' NITROSO]CARBAMOYL]GLYCYL 19 NORTESTOSTERONE; ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; TESTOSTERONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DRUG SYNTHESIS; MALE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CARCINOMA; RAT; RECEPTOR AFFINITY; SUBCUTANEOUS DRUG ADMINISTRATION; WEIGHT REDUCTION;

AMINO ACIDS; ANIMALS; ANTINEOPLASTIC AGENTS; MALE; NANDROLONE; PROSTATIC NEOPLASMS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ANDROGEN; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA;

EID: 0031663615     PISSN: 02669536     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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