Raman detection of macular carotenoid pigments in intact human retina

Investigative Ophthalmology and Visual Science

Volumn 39, Issue 11, 1998, Pages 2003-2011

  Bernstein, Paul S ^a   Yoshida, Mihoko D ^b   Katz, Nikita B ^a   McClane, Robert W ^b   Gellermann, Werner ^b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAROTENOID; XANTHOPHYLL; ZEAXANTHIN;

ARTICLE; BLINDNESS; CONTRAST ENHANCEMENT; CRITICAL FLICKER FUSION; DIAGNOSTIC TEST; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PSYCHOPHYSIOLOGY; RAMAN SPECTROMETRY; RETINA MACULA AGE RELATED DEGENERATION; RETINA MACULA LUTEA; VISUAL ACUITY;

ANIMALS; BETA CAROTENE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; LUTEIN; MACULA LUTEA; RANA PIPIENS; RETINA; RETINAL PIGMENTS; SPECTRUM ANALYSIS, RAMAN; XANTHOPHYLLS;

EID: 0031661348     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Snodderly DM, Brown PK, Delori FC, Auran JD. The macular pigment, I: absorbance spectra, localization, and discrimination from other yellow pigments in primate retinas. Invest Ophthalmol Vis Sci. 1984;25:660-673.
2. Snodderly DM, Auran JD, Delori FC. The macular pigment, II: spatial distribution in primate retinas. Invest Ophthalmol Vis Sci. 1984;25:674-685.
3. Bone RA, Landrum JT, Tarsis SL. Preliminary identification of the human macular pigment. Vision Res. 1985;25:1531-1535.
4. Handelman GJ, Snodderly DM, Adler AJ, Russett MD, Dratz EA. Measurement of carotenoids in human and monkey retinas. Methods Enzymol. 1992;213:220-230.
5. Gass JDM. Stereoscopic Atlas of Macular Disease. 4th ed. St. Louis, MO: CV Mosby; 1997.
6. Schalch W. Carotenoids in the retina: a review of their possible role in preventing or limiting damage caused by light or oxygen. In: Emerit I, Chance B, eds. Free Radicals and Aging. Basel, Switzerland: Birkhauser-Verlag; 1992:280-298.
7. Snodderly DM. Evidence for protection against age-related macular degeneration by carotenoids and antioxidant vitamins. Am J Clin Nutr. 1995;62(suppl):1448S-1461S.
8. Eye Disease Case Control Study Group. Antioxidant status and age related macular degeneration. Arch Ophthalmol. 1993;111:104-109.
9. Seddon JM, Ajani UA, Sperduto RD, Hiller R, Blair N, Burton TC, Farber MD, Gragoudas ES, Haller J, Miller DT, Yannuzzi LA, Willett W. Dietary carotenoids, vitamins A, C, E and advanced age-related macular degeneration: a multicenter study. JAMA. 1994;272:1413-1420.
10. Landrum JT, Bone RA, Kilburn MD. The macular pigment: a possible role in protection from age-related macular degeneration. Adv Pharmacol. 1997;38:537-556.
11. Hammond BR, Johnson EJ, Russell RM, Krinsky NI, Yeum K-J, Edwards RB, Snodderly DM. Dietary modification of human macular pigment density. Inv Ophthalmol Vis Sci. 1997;38:1795-1801.
12. Hammond BR, Wooten BR, Snodderly DM. Individual variations in the spatial profile of human macular pigment. J. Opt Soc Am A. 1997;14:1187-1196.
13. Koyama Y. Proton nuclear magnetic resonance and Raman spectroscopies of cis-trans-carotenoids from pigment-protein complexes. Methods Enzymol. 1992;213:298-305.
14. Redd DC, Yue KT, Martin LG, Kaufman SL. Raman spectroscopy of human atherosclerotic plaque: implications for laser angioplasty. J Vasc Interv Radiol. 1991;2:247-252.
15. Frank CJ, Redd DCB, Gansler TS, McCreery RL. Characterization of human breast biopsy specimens with near-IR Raman spectroscopy. Anal Chem. 1994;66:319-326.
16. Yu NT, Cai M-Z, Lee B-S, Kuck JFR, McFall-Ngai M, Horwitz J. Resonance Raman detection of a carotenoid in the lens of the deep-sea hatchetfish. Exp Eye Res. 1991;52:475-479.
17. Khachik F, Beecher GR, Goli MB, Lusby WR. Separation and quantification of carotenoids in food. Methods Enzymol. 1992; 213:347-359.
18. 2 lifetime of β-carotene. Chem Phys Lett. 1991;178:89-96.
19. Koyama Y, Takatsuka I, Nakata M, Tasumi M. Raman and infrared spectra of the all-trans, 7-cis, 9-cis, 13-cis and 15-cis isomers of β-carotene: key bands distinguishing stretched or terminal-bent configurations from central-bent configurations. J Raman Spectroscopy. 1988;19:37-49.
20. Delori FC, Parker JS, Mainster MA. Light levels in fundus photography and fluorescein angiography. Vision Res. 1980;20:1099-1104.
21. ANSI Z136.1-1993. American National Standards for Safe Use of Laser. New York, NY: American National Standards Institute; 1993.
22. Bridges CDB. Storage, distribution and utilization of vitamins A in the eyes of adult amphibians and tadpoles. Vision Res. 1975;15:1311-1323.
23. Matthies R. Biological applications of resonance Raman spectroscopy in the visible and ultraviolet: vision pigments, purple membrane, and nucleic acids. Chem Biochem Applic Laser. 1979;4:55-99.