Detection of Tn917-like sequences within a Tn916-like conjugative transposon (Tn3872) in erythromycin-resistant isolates of Streptococcus pneumoniae

Antimicrobial Agents and Chemotherapy

Volumn 42, Issue 9, 1998, Pages 2312-2318

  McDougal, Linda K ^a   Tenover, Fred C ^a,d   Lee, Linda N ^b   Rasheed, J Kamlle ^a   Patterson, Jan E ^b   Jorgensen, James H ^b   Leblanc, Donald J ^c  

^a NATIONAL CENTER FOR EMERGING AND ZOONOTIC INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c INDIANA UNIVERSITY SCHOOL OF DENTISTRY   (United States)

^d CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROMYCIN; KANAMYCIN; LINCOSAMIDE; MACROLIDE; MIKAMYCIN B;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM ISOLATION; DNA DNA HYBRIDIZATION; DNA FLANKING REGION; GENE DELETION; GENE INSERTION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; STREPTOCOCCUS PNEUMONIAE; TRANSPOSON;

EID: 0031660991     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.42.9.2312     Document Type: Article

References (66)

1. Anderson, D. G., and L. L. McKay. 1983. Simple and rapid method for isolating large plasmid DNA from lactic streptococci. Appl. Environ. Microbiol. 46:549-552.
2. Ayoubi, P., A. O. Kilic, and M. N. Vijayakumar. 1991. Tn5253, the pneumococcal Ω (cat tet) BM6001 element, is a composite structure of two conjugative transposons, Tn5251 and Tn5252. J. Bacteriol. 173:1617-1622.
3. Banai, M. K., and D. J. LeBlanc. 1984. Streptococcus faecalis R plasmid pJH1 contains an erythromycin resistance transposon (Tn3871) similar to transposon Tn917. J. Bacteriol. 158:1172-1174.
4. Birnboim, H. C., and J. Doly. 1979. A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res. 7:1513-1523.
5. Buu-Hoi, A., and T. Horodniceanu. 1980. Conjugative transfer of multiple antibiotic resistance markers in Streptococcus pneumoniae. J. Bacteriol. 143: 313-320.
6. Caillaud, F., C. Carlier, and P. Courvalin. 1987. Physical analysis of the conjugative shuttle transposon Tn1545. Plasmid 17:58-60.
7. Christie, P. J., R. Z. Korman, S. A. Zahler, J. C. Adsit, and G. M. Dunny. 1987. Two conjugation systems associated with Streptococcus faecalis plasmid pCF10: identification of a conjugative transposon that transfers between S. faecalis and Bacillus subtilis. J. Bacteriol. 169:2529-2536.
8. Clermont, D., and T. Horaud. 1994. Genetic and molecular studies of a composite chromosomal element (Tn3705) containing a Tn916-modified structure (Tn3704) in Streptococcus anginosus F22. Plasmid 31:40-48.
9. Clewell, D. B., F. Y. An, B. A. White, and C. Gawron-Burke. 1985. Streptococcus faecalis sex pheromone (cAM373) also produced by Staphylococcus aureus and identification of a conjugative transposon (Tn918). J. Bacteriol. 162:1212-1220.
10. Clewell, D. B., S. E. Flannagan, and D. D. Jaworski. 1995. Unconstrained bacterial promiscuity: the Tn916-Tn1545 family of conjugative transposons. Trends Microbiol. 3:229-236.
11. Clewell, D. B., and C. Gawron-Burke. 1986. Conjugative transposons and the dissemination of antibiotic resistance in streptococci. Annu. Rev. Microbiol. 40:635-659.
12. Clewell, D. B., P. K. Tomich, M. C. Gawron-Burke, A. E. Franke, Y. Yagi, and F. Y. An. 1982. Mapping of Streptococcus faecalis plasmids pAD1 and pAD2 and studies relating to transposition of Tn917. J. Bacteriol. 152:1220-1230.
13. Courvalin, P., and C. Carlier. 1986. Transposable multiple antibiotic resistance in Streptococcus pneumoniae. Mol. Gen. Genet. 205:291-297.
14. de Barbeyrac, B., M. Dupon, P. Rodriguez, H. Renaudin, and C. Bébéar. 1996. A Tn1545-like transposon carries the tet(M) gene in tetracycline resistant strains of Bacteroides ureolyticus as well as Ureaplasma urealyticum but not Neisseria gonorrhoeae. J. Antimicrob. Chemother. 37:223-232.
15. Facklam, R. R., and R. B. Carey. 1985. Streptococci and aerococci, p. 154-175. In E. H. Lennette, A. Balows, W. J. Hausler, Jr., and H. J. Shadomy (ed.), Manual of clinical microbiology, 4th ed. American Society for Microbiology, Washington, D.C.
16. Fitzgerald, G. F., and D. B. Clewell. 1985. A conjugative transposon (Tn919) in Streptococcus sanguis. Infect. Immun. 47:415-420.
17. Flannagan, S. E., L. A. Zitzow, Y. A. Su, and D. B. Clewel. 1994. Nucleotide sequence of the 18-kb conjugative transposon Tn916 from Enterococcus faecalis. Plasmid 32:350-354.
18. Fletcher, H. M., L. Marri, and L. Daneo-Moore. 1989. Transposon-916-like elements in clinical isolates of Enterococcus faecium. J. Gen. Microbiol. 135:3067-3077.
19. Franke, A. E., and D. B. Clewell. 1981. Evidence for a chromosome-borne resistance transposon (Tn916) in Streptococcus faecalis that is capable of "conjugal" transfer in the absence of a conjugative plasmid. J. Bacteriol. 145:494-502.
20. Gawron-Burke, C., and D. B. Clewell. 1982. A transposon in Streptococcus faecalis with fertility properties. Nature 300:281-284.
21. Guild, W. R., M. D. Smith, and N. B. Shoemaker. 1982. Conjugative transfer of chromosomal R determinants in Streptococcus pneumoniae, p. 88-92. In D. Schlessinger (ed.), Microbiology - 1982. American Society for Microbiology, Washington, D.C.
22. Hofmann, J., M. S. Cetron, M. M. Farley, W. S. Baughman, R. R. Facklam, J. A. Elliott, K. A. Deaver, and R. F. Breiman. 1995. The prevalence of drug-resistant Streptococcus pneumoniae in Atlanta. N. Engl. J. Med. 333: 481-486.
23. Horaud, T., F. Delbos, and G. de Cespedes. 1990. Tn3702, a conjugative transposon in Enterococcus faecalis. FEMS Microbiol. Lett. 72:189-194.
24. Inamine, J. M., and V. Burdett. 1985. Structural organization of a 67-kilobase streptococcal conjugative element mediating multiple antibiotic resistance. J. Bacteriol. 161:620-626.
25. Jorgensen, J. H., J. M. Swenson, F. C. Tenover, M. J. Ferraro, J. A. Hindler, and P. R. Murray. 1994. Development of interpretive criteria and quality control limits for broth microdilution and disk diffusion antimicrobial susceptibility testing of Streptococcus pneumoniae. J. Clin. Microbiol. 32:2448-2459.
26. Kanavaki, S., S. Karabela, E. Marinis, and N. J. Legakis. 1994. Antibiotic resistance of clinical isolates of Streptococcus pneumoniae in Greece. J. Clin. Microbiol. 32:3056-3058.
27. Kell, C. M., J. Z. Jordens, M. Daniels, T. J. Coffey, J. Bates, J. Paul, C. Gilks, and B. G. Spratt. 1993. Molecular epidemiology of penicillin-resistant pneumococci isolated in Nairobi, Kenya. Infect. Immun. 61:4382-4391.
28. Klugman, K. 1990. Pneumococcal resistance to antibiotics. Clin. Microbiol. Rev. 3:171-196.
29. Klugman, K. P., T. J. Coffey, and A. Smith. 1994. Cluster of an erythromycin-resistant variant of the Spanish multiply resistant 23F clone of Streptococcus pneumoniae in South Africa. Eur. J. Clin. Microbiol. Infect. Dis. 13:171-174.
30. LeBlanc, D. J., J. M. Inamine, and L. N. Lee. 1986. Broad geographical distribution of homologous erythromycin, kanamycin, and streptomycin resistance determinants among group D streptococci of human and animal origin. Antimicrob. Agents Chemother. 29:549-555.
31. LeBlanc, D. J., J. H. Jorgensen, J. E. Patterson, A. Abu-Al-Jaibat, L. N. Lee, L. K. McDougal, and F. C. Tenover. 1996. Erythromycin-resistant Streptococcus pneumoniae isolates carrying a Tn917-like transposon, abstr. A107, p. 152. In Abstracts of the 96th General Meeting of the American Society for Microbiology 1996. American Society for Microbiology, Washington, D.C.
32. LeBlanc, D. J., and L. N. Lee. 1986. Characterization of two tetracycline resistance determinants in Streptococcus faecalis JH1. J. Bacteriol. 150:835-843.
33. Le Bouguenec, C., G. de Cespedes, and T. Horaud. 1988. Molecular analysis of a composite chromosomal conjugative element (Tn3701) of Streptococcus pyogenes. J. Bacteriol. 170:3930-3936.
34. Le Bouguenec, C., G. de Cespedes, and T. Horaud. 1990. Presence of chromosomal elements resembling the composite structure Tn3701 in streptococci. J. Bacteriol. 172:727-734.
35. Martin, P., P. Trieu-Cuot, and P. Courvalin. 1986. Nucleotide sequence of the tet(M) tetracycline resistance determinant of the streptococcal conjugative shuttle transposon Tn1545. Nucleic Acids Res. 14:7047-7058.
36. McDougal, L. K., R. Facklam, M. Reeves, S. Hunter, J. M. Swenson, B. C. Hill, and F. C. Tenover. 1992. Analysis of multiply antimicrobial-resistant isolates of Streptococcus pneumoniae from the United States. Antimicrob. Agents Chemother. 36:2176-2184.
37. McDougal, L. K., J. K. Rasheed, J. W. Biddle, and F. C. Tenover. 1996. Identification of multiple clones of extended-spectrum cephalosporin-resistant Streptococcus pneumoniae in the United States. Antimicrob. Agents Chemother. 39:2282-2288.
38. Miller, S. A., D. D. Dykes, and H. F. Polesky. 1988. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 16:1215.
39. Muñoz, R., T. J. Coffey, M. Daniels, C. G. Dowson, G. Laible, J. Casal, R. Hakenbeck, M. Jacobs, J. M. Musser, B. G. Spratt, and A. Tomasz. 1990. Intercontinental spread of a multiresistant clone of serotype 23F Streptococcus pneumoniae. J. Infect. Dis. 164:302-306.
40. Murray, B. E., F. Y. An, and D. B. Clewell. 1988. Plasmids and pheromone response of the β-lactamase producer Streptococcus (Enterococcus) faecalis HH22. Antimicrob. Agents Chemother. 32:547-551.
41. National Committee for Clinical Laboratory Standards. 1997. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, 4th ed. Approved standard M7-A4. National Committee for Clinical Laboratory Standards, Wayne, Pa.
42. Norgren, M., and J. R. Scott. 1991. The presence of conjugative transposon Tn916 in the recipient strain does not impede transfer of a second copy of the element. J. Bacteriol. 173:319-324.
43. Ochman, H., A. S. Gerber, and D. L. Hart. 1988. Genetic applications of an inverse polymerase chain reaction. Genetics 120:621-623.
44. Oggioni, M. R., C. G. Dowson, J. M. Smith, R. Provvedi, and G. Pozzi. 1996. The tetracycline resistance gene tet(M) exhibits mosaic structure. Plasmid 35:156-163.
45. Olsvik, B., F. C. Tenover, I. Olsen, and J. K. Rasheed. 1996. Three subtypes of the tet(M) gene identified in bacterial isolates from periodontal pockets. Oral Microbiol. Immunol. 5:299-303.
46. Poyart-Salmeron, P., P. Trieu-Cuot, C. Carlier, and P. Courvalin. 1990. The integration-excision system of the conjugative transposon Tn1545 is structurally and functionally related to those of lambdoid phages. Mol. Microbiol. 4:1513-1520.
47. Rice, L. B., S. H. Marshall, and L. L. Carias. 1992. Tn5381, a conjugative transposon identifiable as a circular form in Enterococcus faecalis. J. Bacteriol. 174:7308-7315.
48. Roberts, M. C. 1990. Characterization of the tet(M) determinants in urogenital and respiratory bacteria. Antimicrob. Agents Chemother. 34:476-478.
49. Rollins, L. D., L. N. Lee, and D. J. LeBlanc. 1985. Evidence for a disseminated erythromycin resistance determinant mediated by Tn917-like sequences among group D streptococci isolated from pigs, chickens, and humans. Antimicrob. Agents Chemother. 27:439-444.
50. Rubens, C. E., and L. M. Heggen. 1988. Tn916ΔE: a Tn916 transposon derivative expressing erythromycin resistance. Plasmid 20:137-142.
51. Ruoff, K. L. 1995. Streptococci, p. 299-307. In P. R. Murray, E. J. Baron, M. A. Pfaller, F. C. Tenover, and R. H. Yolken (ed.), Manual of clinical microbiology, 6th ed. American Society for Microbiology, Washington, D.C.
52. Salyers, A. A., N. B. Shoemaker, A. M. Stevens, and L. Li. 1995. Conjugative transposons: an unusual and diverse set of integrated gene transfer elements. Microbiol. Rev. 59:579-590.
53. Scott, J. R., and G. G. Churchward. 1995. Conjugative transposition. Annu. Rev. Microbiol. 49:367-397.
54. Shaw, J. H., and D. B. Clewell. 1985. Complete nucleotide sequence of macrolide-lincosamide-streptogramin B-resistance transposon Tn917 in Streptococcus faecalis. J. Bacteriol. 164:782-796.
55. Soares, S., K. G. Kristinsson, J. M. Musser, and A. Tomasz. 1993. Evidence for the introduction of a multiresistant clone of serotype 6B Streptococcus pneumoniae from Spain to Iceland in the late 1980s. J. Infect. Dis. 168:158-163.
56. Su, Y. A., and D. B. Clewell. 1993. Characterization of the left 4 kb of conjugative transposon Tn916: determinants involved in excision. Plasmid 30:234-250.
57. Sutcliffe, J., A. Tait-Kamradt, and L. Wondrack. 1996. Streptococcus pneumoniae and Streptococcus pyogenes resistant to macrolides but sensitive to clindamycin: a common resistance pattern mediated by an efflux system. Antimicrob. Agents Chemother. 40:1817-1824.
58. Swartley, J. S., C. F. McAllister, R. A. Hajjeh, D. W. Heinrich, and D. S. Stephens. 1993. Deletions of Tn916-like transposons are implicated in tet(M)-mediated resistance in pathogenic Neisseria. Mol. Microbiol. 10:299-310.
59. Tomich, P. K., F. Y. An, and D. B. Clewell. 1980. Properties of erythromycin-inducible transposon Tn917 in Streptococcus faecalis. J. Bacteriol. 141:1366-1374.
60. Trieu-Cuot, R., and P. Courvalin. 1983. Nucleotide sequence of the Streptococcus faecalis plasmid gene encoding the 3′5′-aminoglycoside phosphotransferase type III. Gene 23:331-341.
61. Trieu-Cuot, R., and P. Courvalin. 1990. Nucleotide sequence of the erythromycin resistance gene of the conjugate transposon Tn1545. Nucleic Acids Res. 18:3660.
62. Van de Klundert, J. A. M., and J. S. Vliegenthart. 1993. PCR detection of genes coding for aminoglycoside-modifying enzymes, p. 547-552. In D. H. Persing, T. F. Smith, F. C. Tenover, and T. J. White (ed.), Diagnostic molecular microbiology: principles and applications. American Society for Microbiology, Washington, D.C.
63. Vijayakumar, M. N., S. D. Priebe, and W. R. Guild. 1986. Structure of a conjugative element in Streptococcus pneumoniae. J. Bacteriol. 166:978-984.
64. Vijayakumar, M. N., S. D. Priebe, G. Pozzi, J. M. Hageman, and W. R. Guild. 1986. Cloning and physical characterization of chromosomal conjugative elements in streptococci. J. Bacteriol. 166:972-977.
65. Weisblum, B. 1995. Erythromycin resistance by ribosome modification. Antimicrob. Agents Chemother. 39:577-585.
66. Yoshida, R., M. Kaku, S. Kohno, K. Ishida, R. Mizukane, H. Takemura, H. Tanaka, T. Usui, K. Tomono, H. Koga, and K. Hara. 1995. Trends in antimicrobial resistance of Streptococcus pneumoniae in Japan. Antimicrob. Agents Chemother. 39:1196-1198.