The Membrane Proximal Region of the Integrin β Cytoplasmic Domain Can Mediate Oligomerization

Cell Communication and Adhesion

Volumn 5, Issue 5, 1998, Pages 335-347

  Zage, Peter E ^a   Marcantonio, Eugene E ^a,b  

^a Columbia University ^*  (United States)

^b Black Bldg 1427 ^*  (United States)

Author keywords

Cytoplasmic domains; Integrin receptors; Oligomerization

Indexed keywords

CELL MEMBRANE PROTEIN; CHIMERIC PROTEIN; INTEGRIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CYTOPLASM; HUMAN; HUMAN CELL; LIGAND BINDING; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD29; CARRIER PROTEINS; CELL ADHESION MOLECULES; CELLS, CULTURED; CHICKENS; CYTOPLASM; FIBRONECTINS; FLUORESCENT ANTIBODY TECHNIQUE; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GENE DELETION; HUMANS; INTERMEDIATE FILAMENT PROTEINS; KIDNEY; MOLECULAR SEQUENCE DATA; MUTAGENESIS; OLIGONUCLEOTIDES; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE KINASES; RATS; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; SOLUBILITY; TRANSFECTION;

EID: 0031659894     PISSN: 10615385     EISSN: None     Source Type: Journal    
DOI: 10.3109/15419069809010780     Document Type: Article

References (54)

1. Akiyama S.K., Yamada S.S., Yamada KM. and LaFlamme S.E. (1994) Transmembrane Signal Transduction by Integrin Cytoplasmic Domains Expressed in Single-Subunit Chimeras. Journal of Biological Chemistry 269, 15961-4.
2. Argraves W.S., Suzuki S, Arai H., Thompson K., Pierschbacher M.D. and Ruoslahti E. (1987) Amino Acid Sequence of the Human Fibronectin Receptor. J. Cell Biol. 105, 1183-90.
3. Baron M.D., Davison M.D., Jones P and Critchley D.R. (1987) The Sequence of Chick α-Actinin Reveals Homologies to Spectrin and Calmodulin. Journal of Biological Chemistry 262, 17623-9.
4. Briesewitz R., Kern A. and Marcantonio E.E. (1993) Ligand-Dependent and -Independent Integrin Focal Contact Localization: The Role of the α Chain Cytoplasmic Domain. Mol. Biol. Cell 4, 593-604.
5. Briesewitz R., Kern A. and Marcantonio E.E. (1995) Assembly and Function of Integrin Receptors Is Dependent on Opposing α and β Cytoplasmic Domains. Mol. Biol. Cell 6, 997-1010.
6. FAK. Journal of Biological Chemistry 269, 20567-74
7. Chen H.-C., Appeddu P.A., Parsons J.T., Hildebrand J.D., Schaller M.D. and Guan J.-L. (1995) Interaction of Focal Adhesion Kinase with Cytoskeletal Protein Talin. Journal of Biological Chemistry 270, 16995-9.
8. Chin S.S.M., Macioce P. and Liem R.K H (1991) Effects of Truncated Neurofilament Proteins on the Endogenous Intermediate Filaments in Trancfected Fibroblasts. J Cell Sci. 99, 335-50.
9. Coutu M.D. and Craig S.W. (1988) cDNA-Derived Sequence of Chicken Embryo Vinculin. Proceedings of the National Academy of Sciences in the U.S.A. 85, 8535-9.
10. Fitzgerald L.A., Steiner B., Rall S.C., Lo S.-S and Phillips D.R (1987) Protein Sequence of Endothelial Glycoprotein IIIa Derived from a cDNA Cone. Journal of Biological Chemistry, 262, 3936-9.
11. Fliegner K.H., Ching G.Y. and Liem R.K.H. (1990) The Predicted Amino Acid Sequence of α-Internexin Is That of a Novel Neuronal Intermediate Filament Protein. European Molecular Biology Organization Journal, 9, 749-55.
12. Fuchs E. and Weber K. (1994) Intermediate Filaments: Structure, Dynamics. Function, and Disease. Annual Review of Biochemistry 63, 345-82.
13. Gill S.R., Wong P.C., Monteiro M.J. and Cleveland D.W. (1990) Assembly Properties of Dominant and Recessive Mutations in the Small Mouse Neurofilament (NF-L) Subunit. J. Cell Biol. 111, 2005-19.
14. Guan J.-L., Trevithick J.E. and Hynes R.O. (1991) Fibronectin/Integrin Interaction Induces Tyrosine Phosphorylation of a 120kD Protein. Cell Regulation 2, 951-64.
15. Heldin C.-H. (1995) Dimerization of Cell Surface Receptors in Signal Transduction. Cell 80, 213-23.
16. Hibbs M.L., Jakes S., Stacker S.A., Wallace R.W. and Springer T A. (1991) The Cytoplasmic Domain of the Integrin Lymphocyte Function-Associated Antigen 1 β Subunit: Sites Required for Binding to Intercellular Adhesion Molecule 1 and the Phorbol Ester-Stimulated Phosphorylation Site. Journal of Experimental Medicine, 174, 1227-38.
17. FAK, To Cellular Focal Adhesions J. Cell Biol. 123.
18. Horton R.M , Cai Z.L., Ho S.N. and Pease L.R. (1990) Generation of Mutant cDNA by Overlapping PCR. Biotechniques 5, 528-35.
19. Horwitz A., Duggan K., Buck C., Beckerle M.C. and Burridge K. (1986) Interaction of Plasma Membrane Fibronectin Receptor with Talin - A Transmembrane Linkage. Nature 320, 531-3.
20. Hughes P.E., O'Toole T.E., Ylanne J., Shattil S.J. and Ginsberg M.H. (1995) The Conserved Membrane-Proximal Region of an Integrin Cytoplasmic Domain Specifies Ligand Binding Affinity. Journal of Biological Chemistry, 270, 12411-7
21. Hynes R.O. (1992) Integrins: Versatility, Modulation, and Signaling in Cell Adhesion. Cell 69, 11-25.
22. Hynes R.O , Marcantonio E E., Stepp M.A., Urry L.A. and Yee G.E. (1989) Integrin Heterodimer and Receptor Complexity in Avian and Mammalian Cells. J. Cell Biol., 109, 409-20.
23. 1 Integrins. Proceedings of the National Academy of Sciences in the U.S.A., 88, 8392-6.
24. Laemmli U.K. (1970) Cleavage of Structural Proteins During the Assembly of the Head of the Bacteriophage T4. Nature 227, 680-5.
25. LaFlamme S F., Akiyama S.K. and Yamada K.M. (1992) Regulation of Fibronectin Receptor Distribution. J. Cell Biol. 117, 437-47.
26. Lewis J.M. and Schwartz M.A. (1995) Mapping In Vivo Associations of Cytoplasmic Proteins with Integrin β1 Cytoplasmic Domain Mutants. Mol. Biol. Cell. 6, 151-60.
27. Lub M., van Kooyk Y., van Vliet S.J. and Figdor C.G. (1997) Dual Role of the Actin Cytoskeleton in Regulating Cell Adhesion Mediated by the Integrin Lymphocyte Function-Associated Molecule-1. Mol Biol Cell, 8, 341-51.
28. 1 Integrin Cytoplasmic Domain. Journal of Biological Chemistry, 269, 18311-4.
29. 1 Cytoplasmic Domain by Site-Directed Mutagenesis. Cell Regulation, 1, 597-604.
30. 1 Subunit React with Proteins in Vertebrates, Invertebrates, and Fungi. J. Cell Biol., 106, 1765-72.
31. McNamee H.P., Ingber D.E and Schwartz M.A. (1993) Adhesion to Fibronectin Stimulates Inositol Lipid Synthesis and Enhances PDGF-Induced Inositol Lipid Breakdown. J Cell Biol. 121, 673-8.
32. Miyamoto S., Akiyama S.K. and Yamada K.M. (1995) Synergistic Roles for Receptor Occupancy and Aggregation in Integrin Transmembrane Function. Science 267, 883-5.
33. Miyamoto S., Teramoto H., Coso O.A., Gutkind J.S., Burbelo P.D., Akiyama S.K. and Yamada K.M. (1995) Integrin Function: Molecular Hierarchies of Cytoskeletal and Signaling Molecules. J. Cell Biol. 131, 791-805.
34. Miyamoto S., Teramoto H., Gutkind J.S. and Yamada K.M. (1996) Integrins Can Collaborate with Growth Factors for Phosphorylation of Receptor Tyrosine Kinases and MAP Kinase Activation: Roles of Integrin Aggregation and Occupancy of Receptors. J. Cell Biol. 135, 1633-42.
35. IIb. Science 254, 845-7.
36. 1 Integrin Subunit In Vitro. J. Cell Biol 111, 721-9
37. Pear W S., Nolan G.P., Scott M.L. and Baltimore D. (1993) Production of High-Titer Helper-Free Retroviruses by Transient Transfection Proceedings of the National Academy of Sciences in the U.S A. 90, 8392-6.
38. Plopper G.E., McNamee H.P., Dike L.E., Bojanowski K. and Ingber D.E. (1995) Convergence of Integrin and Growth Factor Receptor Signaling Pathways Within the Focal Adhesion Complex. Mol Biol. Cell 6, 1349-65.
39. Rees D.J., Ades S.J., Singer S.J. and Hynes R.O. (1990) Sequence and Domain Structure of Talin. Nature 347, 685-9.
40. Reszka A.A., Hayashi Y. and Horwitz A.F. (1992) Identification of Amino Acid Sequences in the Integrin β1 Cytoplasmic Domain Implicated in Cytoskeletal Association. J. Cell Biol. 117, 1321-30.
41. Sastry S.K. and Horwitz A.F. (1993) Integrin Cytoplasmic Domains: Mediators of Cytoskeletal Linkages and Extra- and Intracellular Initiated Trausmembrane Signaling. Current Opinion in Cell Biology 5, 819-31.
42. FAK. a Structurally Distinctive Protein-Tyrosine Kinase Associated with Focal Adhesions. Proceedings of the National Academy of Sciences in the U.S.A. 89, 5192-6.
43. Schwartz M.A. (1993) Spreading of Human Endothelial Cells on Fibronectin or Vitronectin Triggers Elevation of Intracellular Free Calcium. J. Cell Biol. 120, 1003-10.
44. 1. Independent of Cell Shape. Proceedings of the National Academy of Sciences in the U.S.A 88, 7849-53.
45. 3 Subunits Are Functionally Interchangeable. J. Cell Biol. 114, 1079-88.
46. Solowska J., Guan J.-L., Marcantonio E.E., Trevithick J.E., Buck C A and Hynes R O. (1989) Expression of Normal and Mutant Avian Integrin Subunits in Rodent Cells. J. Cell Biol 109, 853-61.
47. Sonnenberg A. (1993) Integrins and Their Ligands. Current Topics in Microbiology and Immunology 184, 7-35
48. Steinert P.M. and Parry D.A.D. (1985) Intermediate Filaments: Conformity and Diversity of Expression and Structure. Annual Review of Cell Biology 1, 41-65.
49. Steinert P.M. and Roop D.R. (1988) Molecular and Cellular Biology of Intermediate Filaments. Annual Review of Biochemistry 57, 593-625.
50. Tamkun J.W., DeSimone D.W , Fonda D., Patel R.S., Buck C.A., Horwitz A.F. and Hynes R.O. (1986) Structure of Integrin, a Glycoprotein Involved in the Transmembrane Linkage Between Fibronectin and Actin. Cell 46, 271-82.
51. Towbin H., Staehelin T. and Gordon J. (1979) Electrophoretic Transfer from Polyacrylamide Gels to Nitrocellulose Sheets. Proceedings of the National Academy of Sciences in the U.S.A. 76, 4350-4.
52. Wary K.K., Mainiero F., Isakoff S J., Marcantonio E.E. and Giancotti F.G. (1996) The Adaptor Protein She Couples a Class of Integrins to the Control of Cell Cycle Progression. Cell 87, 733-43.
53. Wong P.C. and Cleveland D.W. (1990) Characterization of Dominant and Recessive Assembly-Defective Mutations in Mouse Neurofilament NF-M. J. Cell Biol. 111, 1987-2003.
54. Yamada K.M. and Miyamoto S. (1995) Integrin Transmembrane Signalling and Cytoskeletal Control. Current Opinion in Cell Biology 7, 681-9.