An effective synthetic route to EF5

Synthetic Communications

Volumn 28, Issue 19, 1998, Pages 3701-3709

  Baird, Ian R ^a,b   Skov, Kirsten A ^b   James, Brian R ^a   Rettig, Steven J ^a   Koch, Cameron J ^c  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 NITROIMIDAZOLE DERIVATIVE; ACETAMIDE DERIVATIVE; FLUORINE DERIVATIVE; PENTANE; PROPANE;

ARTICLE; CELL HYPOXIA; CHEMICAL REACTION; CRYSTAL STRUCTURE; SYNTHESIS; X RAY ANALYSIS;

EID: 0031659330     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1080/00397919808004917     Document Type: Article

References (18)

1. Urtasun, R.C., Chapman, J.D., Raleigh, J.A., Franko, A.J. and Koch, C.J. Int. J. Radiat. Oncol. Biol. Phys. 1986, 12, 1263.
2. Lord, E.M., Harwell, L. and Koch, C.J. Cancer Res. 1993, 53, 5271.
3. Woods, M.L., Koch, C.J. and Lord, E.M. Int. J. Rad. Oncol. Biol. Phys. 1996, 34, 93.
4. Southwick, P.L., Ernst, L.A., Tauriello, E.W., Parker, S.R., Mujumdar, R.B., Mujumdar, S.R., Clever, H.A. and Waggoner, A.S. Cytometry 1990, 11, 418.
5. Koch, C.J., Evans, S.M. and Lord, E.M. Br. J. Cancer 1995, 72, 869.
6. Evans, S.M., Jenkins, W.T., Joiner, B., Lord, E.M. and Koch, C. J. Cancer Res. 1996, 56, 405.
7. Laughlin, K.M., Evans, S.M., Lord, E.M. and Koch, C.J. Journal of Pharmacology and Experimental Therapy 1996 (In Press).
8. Evans, S.M., Joiner, B., Jenkins, W.T., Laughlin, K.M., Lord, E.M. and Koch, C.J. Br. J. Cancer 1995, 72, 875.
9. Rochon, F.D., Kong, P.C., Melanson, R., Skov, K. A. and Farrell, N. Inorg. Chem. 1991, 30, 4531.
10. Clarke, M.J., Bailey, V.M., Doan, P.E., Hiller, C.D., Lachance-Galang, K.J., Daghlian, H., Mandal, S., Bastos, C.M. and Lang, D. Inorg. Chem. 1996, 35, 4896. Chatlas, J., van Eldik, R. and Keppler, B.K. Inorg. Chim. Acta 1995, 233, 59. Anderson, C. and Beauchamp, A.L. Inorg. Chim. Acta 1995, 233, 33.
11. Clarke, M.J., Bailey, V.M., Doan, P.E., Hiller, C.D., Lachance-Galang, K.J., Daghlian, H., Mandal, S., Bastos, C.M. and Lang, D. Inorg. Chem. 1996, 35, 4896. Chatlas, J., van Eldik, R. and Keppler, B.K. Inorg. Chim. Acta 1995, 233, 59. Anderson, C. and Beauchamp, A.L. Inorg. Chim. Acta 1995, 233, 33.
12. Clarke, M.J., Bailey, V.M., Doan, P.E., Hiller, C.D., Lachance-Galang, K.J., Daghlian, H., Mandal, S., Bastos, C.M. and Lang, D. Inorg. Chem. 1996, 35, 4896. Chatlas, J., van Eldik, R. and Keppler, B.K. Inorg. Chim. Acta 1995, 233, 59. Anderson, C. and Beauchamp, A.L. Inorg. Chim. Acta 1995, 233, 33.
13. Matthews, J., Adomat, H., Farrell, N., King, P., Koch, C., Lord, E., Palcic, B., Poulin, N., Sangulin, J. and Skov, K. Br. J. Cancer 1996, 74, S200.
14. Koch, C.J. and Lord, E.M. US Patent #5540908 (1996).
15. Beaman, A.G., Duschinsky, R. and Tautz, W.P. US Patent #3679698 (1972).
16. Orpen, G.A., Brammer, L., Allen, F.H., Kennard, O, Watson, D.G. and Taylor, R. J. Chem. Soc., Dalton Trans. 1989, S31.
17. Husted, D.R. and Ahlbrecht, A.H. J. Am. Chem. Soc. 1953, 75, 1605.
18. Selected bond lengths (Å) with e.s.d.s. in parentheses: C(4)-N(1) 1.457(4); C(5)-N(3) 1.335(3); N(4)-O(3) 1.214(3); C(7)-F(2) 1.358(3); C(8)-F(4) 1.317(4). Supplementary Material: Atomic coordinates, bond lengths and angles, and thermal parameters have been deposited at the Cambridge Crystallographic Data Centre.