Effects of isolation-rearing on locomotion, anxiety and responses to ethanol in Fawn Hooded and Wistar rats

Psychopharmacology

Volumn 139, Issue 3, 1998, Pages 203-209

  Hall, F S ^a   Huang, S ^a   Fong, G W ^a   Pert, A ^b   Linnoila, N ^a  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Anxiety; Ethanol; Fawn Hooded rat; Isolation rearing; Locomotor activity; Wistar rat

Indexed keywords

ALCOHOL;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANXIETY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; HYPERACTIVITY; INTRAPERITONEAL DRUG ADMINISTRATION; LOCOMOTION; MAZE TEST; NONHUMAN; PRIORITY JOURNAL; RAT; REARING; SOCIAL ISOLATION; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ETHANOL; LOCOMOTION; MALE; MAZE LEARNING; PSYCHOMOTOR PERFORMANCE; RATS; RATS, WISTAR; SOCIAL ISOLATION;

EID: 0031658688     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130050705     Document Type: Article

References (42)

1. Ahmed SH, Spampinato U, Stinus L, Le Moal M, Cador M (1993) Social deprivation increases the vulnerability of male Wistar rats to develop behavioural sensitization to d-amphetamine. Behav Pharmacol 4:450-451
2. Altemus M, Smith MA, Diep V, Aulakh C, Murphy DL (1995) Increased mRNA for corticotrophin releasing hormone in the amygdala of Fawn-Hooded rats: a potential animal model of anxiety. Anxiety 1:251-257
3. Aulakh CS, Wozniak KM, Hill JL, Devane CL, Tolliver TJ, Murphy DL (1988) Differential neuroendocrine responses to the 5-HT agonist m-chlorophenylpiperazine in Fawn-Hooded rats relative to Wistar and Sprague-Dawley rats. Neuroendocrinology 48:401-406
4. Berlyne DL (1960) Conflict, arousal and curiosity. McGraw-Hill, New York
5. Bickerdike MJ, Wright IK, Marsden CA (1993) Social isolation attenuates rat forebrain 5-HT release induced by KCl stimulation and exposure to a novel environment. Behav Pharmacol 4:231-236
6. Boyle AE, Gill K, Smith BR, Amit Z (1991) Differential effects of an early housing manipulation on cocaine-induced activity and self-administration in laboratory rats. Pharmacol Biochem Behav 39:269-274
7. Deatherage G (1972) Effects of housing density on alcohol intake in the rat. Physiol Behav 9:55-57
8. Einon D, Tye NC (1975) Chlordiazepoxide and isolation induced timidity in rats. Psychopharmacology 44:83-85
9. Einon DF, Morgan MJ (1978) Early isolation produces enduring hyperactivity in the rat, but no effect upon spontaneous alternation. Q J Exp Psychol 30:151-156
10. Feldon J, Avnimelech-Gigus N, Weiner I (1990) The effects of preand postweaning rearing conditions on latent inhibition and partial reinforcement extinction effect in male rats. Behav Neural Biol 53:189-204
11. Gentsch C, Liehtsteiner M, Feer H (1981) Individual housing of rats causes divergent changes in spontaneous and reactive activity. Experientia 37:61-62
12. Hall FS, Humby T, Wilkinson LS, Robbins TW (1997a) The effects of isolation-rearing of rats on preference for a novel environment. Physiol Behav 62:299-303
13. Hall FS, Humby T, Wilkinson LS, Robbins TW (1997b) The effects of isolation-rearing of rats on sucrose consumption in rats. Physiol Behav 62:291-297
14. Jaffe EH, De Frias V, Ibarra C (1993) Changes in basal and stimulated release of endogenous serotonin from different nuclei of rats subjected to two models of depression. Neurosci Lett 162: 157-160
15. Jones DL, Mogenson GJ, Wu M (1981) Injection of dopaminergic, cholinergic, and GABAergic drugs into the nucleus accumbens: effects on locomotor activity in the rat. Neuropharmacology 20:29-37
16. Jones GH, Robbins TW, Marsden CA (1989) Isolation-rearing retards the acquisition of schedule-induced polydipsia in rats. Physiol Behav 45:71-77
17. Jones GH, Marsden CA, Robbins TW (1990) Increased sensitivity to amphetamine and reward-related stimuli following social isolation in rats: possible disruption of dopamine-dependent mechanisms. Psychopharmacology 102:364-372
18. Jones GH, Marsden CA, Robbins TW (1991) Behavioral rigidity and rule-learning deficits following social isolation in rats: neurochemical correlates. Behav Brain Res 43:35-50
19. Jones GH, Hernandez TD, Kendall DA, Marsden CA, Robbins TW (1992) Dopaminergic and serotonergic function following isolation-rearing in rats: a study of behavioral responses and post-mortem and in vivo neurochemistry. Pharm Biochem Behav 43:17-35
20. Joyce EM, Iversen SD (1984) Dissociable effects of 6-OHDA-induced lesions of neostriatum on anorexia, locomotor activity and stereotypy: the role of behavioural competition. Psychopharmacology 83:363-366
21. Kelley PH, Seviour PW, Iversen SD (1975) Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum. Brain Res 94:507-522
22. Lahmame A, Gomez F, Armario A (1996) Fawn-Hooded rats show enhanced active behaviour in the forced swimming test, with no evidence for pituitary-adrenal axis hyperactivity. Psychopharmacology 125:74-78
23. Lyness WH, Friedle NM, Moore KE (1979) Destruction of dopaminergic nerve terminals in nucleus accumbens: effect on d-amphetamine self-administration. Pharmacol Biochem Behav 11:553-556
24. Lyon M, Robbins TW (1975) The action of central nervous system stimulant drugs: a general theory concerning amphetamine effects. Current developments in psychopharmacology. Spectrum, New York, pp 79-163
25. Maisonnette S, Morato S, Brandao ML (1993) Role of resocialization and of 5-HT1A receptor activation on the anxiogenic effects induced by isolation in the elevated plus-maze test. Physiol Behav 54:753-758
26. Margo AM, Rudofsky UH, Gilboa N, Seegal R (1986) Increased catecholamine output in the hypertensive Fawn-Hooded rat. Lab Anim Sci 36:646-649
27. Morgan MJ, Einon D, Morris RGM (1977) Inhibition and isolation rearing in the rat: extinction and satiation. Physiol Behav 18:1-5
28. Overstreet DH, Rezvani AH, Janowsky DS (1992) Genetic animal models of depression and ethanol preference provide support for cholinergic and serotonergic involvement in depression and alcoholism. Biol Psychiatry 31:919-936
29. Pellow S, Chopin P, File SE, Briley M (1985) Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Meth 14:149-167
30. Pijnenberg AJJ, Honig WMM, Van der Heyden JAM, Van Rossum JM (1976) Effects of chemical stimulation of the mesolimbic dopamine system on locomotor activity. Eur J Pharmacol 35: 45-58
31. Rezvhani AH, Overstreet DH, Janowsky DS (1990) Genetic serotonin deficiency and alcohol preference in the Fawn Hooded rats. Alcohol Alcohol 25:573-575
32. Robbins TW (1977) A critique of the methods available for the measurement of spontaneous motor activity. In: Iversen LL, Iversen SD, Snyder SD (eds) Handbook of psychopharmacology. Plenum Press, New York, pp 37-81
33. Robbins TW, Roberts DCS, Koob GF (1983) Effects of d-amphetamine and apomorphine upon operant behaviour and schedule-induced licking in rats with 6-hydroxydopamine lesions of the nucleus accumbens. J Pharmacol Exp Ther 222:662-673
34. Sahakian BJ, Robbins TW, Morgan MJ, Iversen SD (1975) The effects of psychomotor stimulants on stereotypy and locomotor activity in socially-deprived and control rats. Brain Res 84:195-205
35. Sahakian BJ, Robbins TW, Iversen SD (1977) The effects of isolation rearing on exploration in the rat. Anim Learn Behav 5: 193-198
36. Schlechter MD (1992) Locomotor activity but not conditioned place preference is differentially affected by a moderate dose of ethanol administered to P and NP rats. Alcohol 9:185-188
37. Schenk S, Lucelle G, Gorman K, Amit Z (1987) Cocaine self-administration in rats influenced by environmental conditions: implications for the etiology of drug abuse. Neurosci Lett 81: 227-231
38. Schenk S, Gorman K, Amit Z (1990) Age-dependent effects of isolation housing on the self-administration of ethanol in laboratory rats. Alcohol 7:321-326
39. Syme LA (1973) Social isolation at weaning: some effects on two measures of activity. Anim Learn Behav 1:161-163
40. Waller MB, Murphy JM, McBride WJ, Lumeng L, Li T-K (1986) Effect of low dose ethanol on spontaneous motor activity in alcohol-preferring and nonpreferring lines of rats. Pharmacol Biochem Behav 24:617-623
41. Wolffgramm J (1990) Free choice ethanol intake of laboratory rats under different social conditions. Psychopharmacology 101: 233-239
42. Wright IK, Upton N, Marsden CA (1991) Resocialisation of isolation-reared rats does not alter their anxiogenic profile on the elevated x-maze model of anxiety. Physiol Behav 50:1129-1132