-
1
-
-
0027218689
-
Biochemistry of multidrug resistance mediated by the multidrug transporter
-
GOTTESMAN MM, PASTAN I: Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 62:385-427, 1993
-
(1993)
Annu Rev Biochem
, vol.62
, pp. 385-427
-
-
Gottesman, M.M.1
Pastan, I.2
-
2
-
-
0026570652
-
The role of the MDRI (P-glycoprotein) gene in multidrug resistance in vitro and in vivo
-
RONINSON IB: The role of the MDRI (P-glycoprotein) gene in multidrug resistance in vitro and in vivo. Biochem Pharmacol 43:95-102, 1992
-
(1992)
Biochem Pharmacol
, vol.43
, pp. 95-102
-
-
Roninson, I.B.1
-
3
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
THIEBAUT F, TSURUO T, HAMADA H, GOTTESMAN MM, PASTAN I, WILLINGHAM MC: Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci USA 84:7735-7738, 1987
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
4
-
-
0000712439
-
Multidrug resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites
-
CORDON-CARDO C, O'BRIEN JP, CASALS D, RITTMAN-GRAUER L, BIEDLER JL, MELAMED MR, BERTINO JR: Multidrug resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites. Proc Natl Acad Sci USA 86:695-698, 1989
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 695-698
-
-
Cordon-Cardo, C.1
O'Brien, J.P.2
Casals, D.3
Rittman-Grauer, L.4
Biedler, J.L.5
Melamed, M.R.6
Bertino, J.R.7
-
5
-
-
0028229150
-
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
-
SCHINKEL AH, SMIT JJ, VAN TELLINGEN O, BEIJNEN JH, WAGENAAR E, VAN DEEMTER L, MOL CA, VAN DER VALK MA, ROBANUS-MAANDAG EC, TE RIELE HP, BERNS AJM, BORST P: Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell 77:491-502, 1994
-
(1994)
Cell
, vol.77
, pp. 491-502
-
-
Schinkel, A.H.1
Smit, J.J.2
Van Tellingen, O.3
Beijnen, J.H.4
Wagenaar, E.5
Van Deemter, L.6
Mol, C.A.7
Van Der Valk, M.A.8
Robanus-Maandag, E.C.9
Te Riele, H.P.10
Berns, A.J.M.11
Borst, P.12
-
6
-
-
0028825399
-
Absence of the mdr1a P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin a
-
SCHINKEL AH, WAGENAAR E, VAN DEEMTER L, MOL CA, BORST P: Absence of the mdr1a P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A. J Clin Invest 96:1698-1705, 1995
-
(1995)
J Clin Invest
, vol.96
, pp. 1698-1705
-
-
Schinkel, A.H.1
Wagenaar, E.2
Van Deemter, L.3
Mol, C.A.4
Borst, P.5
-
7
-
-
0027418815
-
Human P-glycoprotein transports cyclosporine A and FK506
-
SAEKI T, UEDA K, TANIGAWARA Y, HORI R, KOMANO T: Human P-glycoprotein transports cyclosporine A and FK506. J Biol Chem 268:6077-6080, 1993
-
(1993)
J Biol Chem
, vol.268
, pp. 6077-6080
-
-
Saeki, T.1
Ueda, K.2
Tanigawara, Y.3
Hori, R.4
Komano, T.5
-
8
-
-
0025893168
-
Calcineurin is a common target of cyclophilin-cyclosporine A and FKBP-FK506 complexes
-
LIU J, FARMER JD JR, LANE WS, FRIEDMAN J, WEISSMAN I, SCHREIBER SL: Calcineurin is a common target of cyclophilin-cyclosporine A and FKBP-FK506 complexes. Cell 66:807-815, 1991
-
(1991)
Cell
, vol.66
, pp. 807-815
-
-
Liu, J.1
Farmer Jr., J.D.2
Lane, W.S.3
Friedman, J.4
Weissman, I.5
Schreiber, S.L.6
-
9
-
-
0024959451
-
Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin
-
TAKAHASHI N, HAYANO T, SUZUKI M: Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin. Nature 337:473-475, 1989
-
(1989)
Nature
, vol.337
, pp. 473-475
-
-
Takahashi, N.1
Hayano, T.2
Suzuki, M.3
-
10
-
-
0024959449
-
Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins
-
FISCHER G, WITTMANN-LIEBOLD B, LANG K, KIEFHABER T, SCHMID FX: Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins. Nature 337:476-478, 1989
-
(1989)
Nature
, vol.337
, pp. 476-478
-
-
Fischer, G.1
Wittmann-Liebold, B.2
Lang, K.3
Kiefhaber, T.4
Schmid, F.X.5
-
11
-
-
0025226638
-
Probing immunosuppressant action with a nonnatural immunophilin ligand
-
BIERER BE, SOMERS PK, WANDLESS TJ, BURAKOFF SJ, SCHREIBER-SL: Probing immunosuppressant action with a nonnatural immunophilin ligand. Science 250:556-559, 1990
-
(1990)
Science
, vol.250
, pp. 556-559
-
-
Bierer, B.E.1
Somers, P.K.2
Wandless, T.J.3
Burakoff, S.J.4
Schreiber, Sl.5
-
12
-
-
0025337882
-
FK 506 dosage in human organ transplantation
-
JAIN AB, FUNG JJ, VENKATARAMANAN R, TODO S, ALESSIANI M, STARZL TE: FK 506 dosage in human organ transplantation. Transplant Proc 22:23-24, 1990
-
(1990)
Transplant Proc
, vol.22
, pp. 23-24
-
-
Jain, A.B.1
Fung, J.J.2
Venkataramanan, R.3
Todo, S.4
Alessiani, M.5
Starzl, T.E.6
-
13
-
-
0030893367
-
Tacrolimus rescue therapy for renal allograft rejection: Five-year experience
-
JORDAN ML, NARAGHI R, SHAPIRO R, SMITH D, VIVAS CA, SCANTLEBURY VP, GRITSCH HA, MCCAULEY J, RANDHAWA P, DEMETRIS AJ, MCMICHAEL J, FUNG JJ, STARZL TE: Tacrolimus rescue therapy for renal allograft rejection: Five-year experience. Transplantation 63: 223-228, 1997
-
(1997)
Transplantation
, vol.63
, pp. 223-228
-
-
Jordan, M.L.1
Naraghi, R.2
Shapiro, R.3
Smith, D.4
Vivas, C.A.5
Scantlebury, V.P.6
Gritsch, H.A.7
Mccauley, J.8
Randhawa, P.9
Demetris, A.J.10
Mcmichael, J.11
Fung, J.J.12
Starzl, T.E.13
-
14
-
-
0027439668
-
The histopathological changes associated with allograft rejection and drug toxicity in renal transplant recipients maintained on FK506. Clinical significance and comparison with cyclosporine
-
RANDHAWA PS, SHAPIRO R, JORDAN ML, STARZL TE, DEMETRIS AJ: The histopathological changes associated with allograft rejection and drug toxicity in renal transplant recipients maintained on FK506. Clinical significance and comparison with cyclosporine. Am J Surg Pathol 17:60-68, 1493
-
(1493)
Am J Surg Pathol
, vol.17
, pp. 60-68
-
-
Randhawa, P.S.1
Shapiro, R.2
Jordan, M.L.3
Starzl, T.E.4
Demetris, A.J.5
-
15
-
-
0029898275
-
One-year follow-up of an open-label trial of FK506 for primary kidney transplantation. A report of the U.S. Multicenter FK506 Kidney Transplant Group
-
VINCENTI F, LASKOW DA, NEYLAN JF, MENDEZ R, MATAS AJ: One-year follow-up of an open-label trial of FK506 for primary kidney transplantation. A report of the U.S. Multicenter FK506 Kidney Transplant Group. Transplantation 61:1576-158, 1996
-
(1996)
Transplantation
, vol.61
, pp. 1576-2158
-
-
Vincenti, F.1
Laskow, D.A.2
Neylan, J.F.3
Mendez, R.4
Matas, A.J.5
-
16
-
-
0028140134
-
Cyclosporin a nephropathy: Standardization of the evaluation of kidney biopsies
-
MIHATSCH MJ, ANTONOVYCH T, BOHMAN SO, HABIB R, HELMCHEN U, NOEL LM, OLSEN S, SIBLEY RK, KEMENY E, FEUTRIN G: Cyclosporin A nephropathy: Standardization of the evaluation of kidney biopsies. Clin Nephrol 41:23-32, 1994
-
(1994)
Clin Nephrol
, vol.41
, pp. 23-32
-
-
Mihatsch, M.J.1
Antonovych, T.2
Bohman, S.O.3
Habib, R.4
Helmchen, U.5
Noel, L.M.6
Olsen, S.7
Sibley, R.K.8
Kemeny, E.9
Feutrin, G.10
-
17
-
-
0029871110
-
A comparative study of morphological characteristics of renal injuries of tacrolimus (FK506) and cyclosporin (CyA) in renal allografts: Are the morphologic characteristics of FK506 and CyA nephrotoxicity similar?
-
MOROZUMI K, SUGITO K, ODA A, TAKEUCHI O, FUKUDA M, USAMI T, OIKAWA T, FUJINAMI T, KOYAMA K, TAKEDA A, YOSHIDA A, HABA T, TOMINAGA Y, UCHIDA K, YOKOYAMA I, TAKAGI H: A comparative study of morphological characteristics of renal injuries of tacrolimus (FK506) and cyclosporin (CyA) in renal allografts: Are the morphologic characteristics of FK506 and CyA nephrotoxicity similar? Transplant Proc 28:1076-1078, 1996
-
(1996)
Transplant Proc
, vol.28
, pp. 1076-1078
-
-
Morozumi, K.1
Sugito, K.2
Oda, A.3
Takeuchi, O.4
Fukuda, M.5
Usami, T.6
Oikawa, T.7
Fujinami, T.8
Koyama, K.9
Takeda, A.10
Yoshida, A.11
Haba, T.12
Tominaga, Y.13
Uchida, K.14
Yokoyama, I.15
Takagi, H.16
-
18
-
-
0031012546
-
Nephrotoxicity of immunosuppressive drugs: Experimental and clinical observations
-
ANDOH TF, BURDMANN EA, BENNETT WM: Nephrotoxicity of immunosuppressive drugs: Experimental and clinical observations. Semin Nephrol 17:34-45, 1997
-
(1997)
Semin Nephrol
, vol.17
, pp. 34-45
-
-
Andoh, T.F.1
Burdmann, E.A.2
Bennett, W.M.3
-
19
-
-
0027500507
-
Increased mdr-1/P-glycoprotein expression after treatment of human colon carcinoma cells with P-glycoprotein antagonists
-
HERZOG CE, TSOKOS M, BATES SE, FOJO AT: Increased mdr-1/P-glycoprotein expression after treatment of human colon carcinoma cells with P-glycoprotein antagonists. J Biol Chem 268:2946-2952, 1993
-
(1993)
J Biol Chem
, vol.268
, pp. 2946-2952
-
-
Herzog, C.E.1
Tsokos, M.2
Bates, S.E.3
Fojo, A.T.4
-
20
-
-
0029938602
-
Cyclosporin A treatment induces overexpression of P-glycoprotein in the kidney and other tissues
-
JETTÉ BEAULIEU E, LECLERC J-M, BÉLIVEAU R: Cyclosporin A treatment induces overexpression of P-glycoprotein in the kidney and other tissues. Am J Physiol 270:F756-F765, 1996
-
(1996)
Am J Physiol
, vol.270
-
-
Jetté Beaulieu, E.1
Leclerc, J.-M.2
Béliveau, R.3
-
22
-
-
0027423663
-
Differential induction of VCAM-I on human iliac venous and arterial endothelial cells and its role in adhesion
-
HAUSER IA, JOHNSON DR, MADRI JA: Differential induction of VCAM-I on human iliac venous and arterial endothelial cells and its role in adhesion. J Immunol 151:5172-5185, 1993
-
(1993)
J Immunol
, vol.151
, pp. 5172-5185
-
-
Hauser, I.A.1
Johnson, D.R.2
Madri, J.A.3
-
23
-
-
0029830096
-
Immortalization and characterization of proximal tubule cells derived from kidneys of spontaneously hypertensive and normotensive rats
-
WOOST PG, OROSZ DE, JIN W, FRISA PS, JACOBBERGER JW, DOUGLAS JG, HOPFER U: Immortalization and characterization of proximal tubule cells derived from kidneys of spontaneously hypertensive and normotensive rats. Kidnev Int 50:125-134, 1996
-
(1996)
Kidnev Int
, vol.50
, pp. 125-134
-
-
Woost, P.G.1
Orosz, D.E.2
Jin, W.3
Frisa, P.S.4
Jacobberger, J.W.5
Douglas, J.G.6
Hopfer, U.7
-
24
-
-
71849104860
-
Protein measurement with the Folin phenol reagent
-
LOWRY OH, ROSEBROUGH NJ, FARR AL, RANDALL RJ: Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275, 1951
-
(1951)
J Biol Chem
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
25
-
-
0030044189
-
Chloride and potassium conductances of mouse pancreatic zymogen granules are inversely regulated by a ∼80-kDa mdr1a gene product
-
THÉVENOD F, HILDEBRANDT JP, STRIESSNIG J, DEJONGE HR, SCHNULZ I: Chloride and potassium conductances of mouse pancreatic zymogen granules are inversely regulated by a ∼80-kDa mdr1a gene product. J Biol Chem 271:3300-3305, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 3300-3305
-
-
Thévenod, F.1
Hildebrandt, J.P.2
Striessnig, J.3
Dejonge, H.R.4
Schnulz, I.5
-
26
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
LAEMMLI UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685, 1970
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
27
-
-
0027432409
-
Fluorescent cellular indicators are extruded by the multidrug resistance protein
-
HOMOLYA L, HOLLO Z, GERMANN UA, PASTAN I, GOTTESMAN MM, SARKADI B: Fluorescent cellular indicators are extruded by the multidrug resistance protein. J Biol Chem 268:21493-21496, 1993
-
(1993)
J Biol Chem
, vol.268
, pp. 21493-21496
-
-
Homolya, L.1
Hollo, Z.2
Germann, U.A.3
Pastan, I.4
Gottesman, M.M.5
Sarkadi, B.6
-
28
-
-
0021852930
-
Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies
-
KARTNER N, EVERNDEN-PORELLE D, BRADLEY G, LING V: Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies. Nature 316:820-823, 1985
-
(1985)
Nature
, vol.316
, pp. 820-823
-
-
Kartner, N.1
Evernden-Porelle, D.2
Bradley, G.3
Ling, V.4
-
29
-
-
0025141784
-
Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodies
-
GLORGES E, BRADLEY G, GARIEPY J, LING V: Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodies. Proc Natl Acad Sci USA 87:152-156, 1990
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 152-156
-
-
Glorges, E.1
Bradley, G.2
Gariepy, J.3
Ling, V.4
-
30
-
-
0027391633
-
Topology of P-glycoprotein as determined by epitope mapping of MRK-16 monoclonal antibody
-
GEORGES E, TSURUO T, LING V: Topology of P-glycoprotein as determined by epitope mapping of MRK-16 monoclonal antibody. J Biol Chem 268:1792-1798, 1993
-
(1993)
J Biol Chem
, vol.268
, pp. 1792-1798
-
-
Georges, E.1
Tsuruo, T.2
Ling, V.3
-
31
-
-
0025007511
-
Pharmacology of drugs that alter multidrug resistance in cancer
-
FORD JM, HAIT WN: Pharmacology of drugs that alter multidrug resistance in cancer. Pharmacol Rev 42:155-199, 1990
-
(1990)
Pharmacol Rev
, vol.42
, pp. 155-199
-
-
Ford, J.M.1
Hait, W.N.2
-
32
-
-
0031886711
-
MDR1 in taste buds of rat vallate papilla: Functional, immunohistochemical and biochemical evidence
-
JAKOB I, HAUSER IA, THÉVENOD F, LINDEMANN B: MDR1 in taste buds of rat vallate papilla: Functional, immunohistochemical and biochemical evidence. Am J Physiol 274:C182-C191, 1998
-
(1998)
Am J Physiol
, vol.274
-
-
Jakob, I.1
Hauser, I.A.2
Thévenod, F.3
Lindemann, B.4
-
33
-
-
0025103799
-
Competitive interaction of cyclosporins with the Vinca alkaloid-binding site of P-glycoprotein in multidrug-resistant cells
-
TAMAI I, SAFA AR: Competitive interaction of cyclosporins with the Vinca alkaloid-binding site of P-glycoprotein in multidrug-resistant cells. J Biol Chem 265:16509-16513, 1990
-
(1990)
J Biol Chem
, vol.265
, pp. 16509-16513
-
-
Tamai, I.1
Safa, A.R.2
-
34
-
-
4243989501
-
The expression of multidrug resistance P-glycoprotein (mdr1) increases along kidney proximal tubule (PT), and its distribution inverses in cadmium (Cd)-intoxicated rats.
-
THÉVENOD F, HERAK-KRAMBERGER C, SABOLIC I: The expression of multidrug resistance P-glycoprotein (mdr1) increases along kidney proximal tubule (PT), and its distribution inverses in cadmium (Cd)-intoxicated rats. (abstract) FASEB J 11:A460, 1997
-
(1997)
FASEB J
, vol.11
-
-
Thévenod, F.1
Herak-Kramberger, C.2
Sabolic, I.3
-
35
-
-
0026327395
-
Pharmacokinetics of FK 506 in transplant patients
-
VENKATARAMANAN R, JAIN A, WARTY VS, ABU-ELMAGD K, ALESSIANI M, LEVER J, KRAJAK A, FLOWERS J, MEHTA S, ZUCKERMAN S, FUNG J, TODO S, STARZL TD: Pharmacokinetics of FK 506 in transplant patients. Transplant Proc 23:2736-2740, 1991
-
(1991)
Transplant Proc
, vol.23
, pp. 2736-2740
-
-
Venkataramanan, R.1
Jain, A.2
Warty, V.S.3
Abu-Elmagd, K.4
Alessiani, M.5
Lever, J.6
Krajak, A.7
Flowers, J.8
Mehta, S.9
Zuckerman, S.10
Fung, J.11
Todo, S.12
Starzl, T.D.13
-
36
-
-
0021012807
-
Cyclosporine: Pharmacokinetics, metabolism and drug interactions
-
WOOD AJ, MAURER G, NIEDERBERGER W, BEVERIDGE T: Cyclosporine: Pharmacokinetics, metabolism and drug interactions. Transplant Proc 15:2409-2412, 1983
-
(1983)
Transplant Proc
, vol.15
, pp. 2409-2412
-
-
Wood, A.J.1
Maurer, G.2
Niederberger, W.3
Beveridge, T.4
-
37
-
-
0028817068
-
Relationship between P-glycoprotein expression and cyclosporine A in kidney. An immunohistological and cell culture study
-
GARCIA DEL MORAL R, O'VALLE F, ANDUJAR M, AGUILAR M, LUCENA MA, LOPEZ-HIDALGO J, RAMIREZ C, MEDINA-CANO MT, AGUILAR D, GOMEZ-MORALES M: Relationship between P-glycoprotein expression and cyclosporine A in kidney. An immunohistological and cell culture study. Am J Pathol 146:398-408, 1995
-
(1995)
Am J Pathol
, vol.146
, pp. 398-408
-
-
Garcia Del Moral, R.1
O'Valle, F.2
Andujar, M.3
Aguilar, M.4
Lucena, M.A.5
Lopez-Hidalgo, J.6
Ramirez, C.7
Medina-Cano, M.T.8
Aguilar, D.9
Gomez-Morales, M.10
-
38
-
-
0025843705
-
Multidrug resistance in heart transplant patients: A preliminary communication on a possible mechanism of therapy-resistant rejection
-
KEMNITZ J, UYSAL A, HAVERICH A, HEUBLEIN B, COHNERT TR, STANGEL W, GEORGII A: Multidrug resistance in heart transplant patients: A preliminary communication on a possible mechanism of therapy-resistant rejection. J Heart Lung Transplant 10:201-210, 1991
-
(1991)
J Heart Lung Transplant
, vol.10
, pp. 201-210
-
-
Kemnitz, J.1
Uysal, A.2
Haverich, A.3
Heublein, B.4
Cohnert, T.R.5
Stangel, W.6
Georgii, A.7
-
39
-
-
0028804465
-
Expression of the multidrug resistance gene MDR-1 in peripheral blood mononuclear cells from cyclosporine-treated renal transplant recipients rejecting their graft
-
ZANKER B, BARTH, C, MENGES AV, LAMMERDING P, STACHOWSKI J, BALDAMUS CA: Expression of the multidrug resistance gene MDR-1 in peripheral blood mononuclear cells from cyclosporine-treated renal transplant recipients rejecting their graft. Transplant Proc 27:925-926, 1995
-
(1995)
Transplant Proc
, vol.27
, pp. 925-926
-
-
Zanker, B.1
Barth, C.2
Menges, A.V.3
Lammerding, P.4
Stachowski, J.5
Baldamus, C.A.6
-
40
-
-
0030948858
-
Multidrug resistance gene MDR1 expression: A gene transfection in vitro model and clinical analysis in cyclosporine-treated patients rejecting their renal grafts
-
ZANKER B, BARTH C, STACHOWSKI J, BALDAMUS CA, LAND W: Multidrug resistance gene MDR1 expression: A gene transfection in vitro model and clinical analysis in cyclosporine-treated patients rejecting their renal grafts. Transplant Proc 29:1507-1508, 1997
-
(1997)
Transplant Proc
, vol.29
, pp. 1507-1508
-
-
Zanker, B.1
Barth, C.2
Stachowski, J.3
Baldamus, C.A.4
Land, W.5
-
41
-
-
0029806297
-
Chronic cyclosporine nephropathy: The Achilles' heel of immunosuppressive therapy
-
BENNETT WM, DEMATTOS A, MEYER MM, ANDOH T, BARRY JM: Chronic cyclosporine nephropathy: The Achilles' heel of immunosuppressive therapy. Kidney Int 50:1089-1100, 1996
-
(1996)
Kidney Int
, vol.50
, pp. 1089-1100
-
-
Bennett, W.M.1
Demattos, A.2
Meyer, M.M.3
Andoh, T.4
Barry, J.M.5
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