Influence of temperature on the emitted dose of an oral metered dose inhaler

Drug Development and Industrial Pharmacy

Volumn 24, Issue 11, 1998, Pages 1043-1048

  Williams III, Robert O ^a   Barron, Melisa K ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BECLOMETASONE DIPROPIONATE; CHLOROFLUOROCARBON; OLEIC ACID;

AEROSOL; ARTICLE; DEVICE; DRUG DELIVERY SYSTEM; METERED DOSE INHALER; PARTICLE SIZE; TEMPERATURE;

EID: 0031658173     PISSN: 03639045     EISSN: None     Source Type: Journal    
DOI: 10.3109/03639049809089947     Document Type: Article

References (25)

1. G. P. Polli, W. M. Grim, F. A. Bacher, and M. H. Yunker, J. Pharm. Sci., 58:4 484-486, (1969)
2. J. A. Ranucci, D. Cooper, and K. Sethachutkul, Pharm. Tech., 3, 84-92 (1992).
3. P. M. Holzner and B. W. Muller, Int. J. Pharm., 106, 69-75 (1994).
4. T. Martonen, I. Katz, and W. Cress, Pharm. Res., 12:1, 96-102 (1995).
5. A. M. Whelan and N. W. Hahn, DICP, Ann. Pharm., 25: 6, 638-645 (1991).
6. E. M. Phillips and P. R. Byron, Int. J. Pharm., 110, 9-19 (1994).
7. S. P. Newman, P. Moren, D. Pavia, O. Corrado, and S. W. Clarke, Int. J. Pharm., 11, 337-344 (1982).
8. K. J. Harnor, A. C. Perkins, M. Wastie, C. G. Wilson, E. E. Simms, L. C. Feely, and S. J. Fair, Int. J. Pharm., 95, 111-116 (1993).
9. D. June, S. Carlson, and D. Ross, International Symposia of Respiratory Drug Delivery V, Phoenix, AZ, April 28-May 2, 1996, pp. 354-356.
10. X. A. Johnson, Proceedings from the Pharm Tech Conference, Eugene, OR, pp. 66-78, 1992.
11. American Society of Heating, Refrigeration and Air-Conditioning Engineers, Thermophysical Properties of Refrigerants/ASHRAE, 2nd ed., American Society of Heating, Refrigeration and Air-Conditioning Engineers, New York, 1976, pp. 207-237.
12. S. I. Sandler, Chemical and Engineering Thermodynamics, John Wiley and Sons, New York, 1977, p. 404.
13. U.S. Pharmacopia-NF XXIII, 7th Suppl., Physical Tests/ (601) Aerosols, pp. 3123-3129.
14. S. P. Newman, M. Killip, D. Pavia, F. Moren, and S. W. Clarke, Int. J. Pharm., 19, 333-337 (1984).
15. J. Heyder, J. Gebhart, G. Rudolf, C. F. Schiller, and W. Stahlhofen, J. Aerosol Sci., 17:5, 811-825 (1986).
16. Task Group on Lung Dynamics, Deposition and Retention Models for Internal Dosimetry of the Human Respiratory Tract, Health Phys., 12, 173 (1966).
17. F. Moren, M. B. Dolovich, M. T. Newhouse, and S. P. Newman, Aerosols in Medicine, Principals, Diagnosis, and Therapy, 2nd ed., Elsevier Science Publishers, 1993, pp. 124-126.
18. C. K. Diu and C. P. Yu, Am. Ind. Hyg. Assoc. J., 44, 62-65 (1983).
19. I. Gonda, J. Pharm. Pharmacol., 33, Suppl. 52P (1981).
20. D. D. Persons, G. D. Hess, W. J. Muller, and D. W. Scherer, J. Appl. Physiol., 63, 1195-1204 (1987).
21. S. P. Newman, D. Pavia, N. Garland, and S. W. Clarke, Eur. J. Respir. Dis., 63, Suppl. 119, 57-65 (1982).
22. C. S. Kim, M. A. Eldridge, L. Garcia, and A. Wanner, J. Appl. Physiol., 67, 2579-2585 (1989).
23. M. Trajan, J. W. Logus, E. G. Enns, and S. F. P. Man, Am. Rev. Resp. Dis., 130, 64-70 (1984).
24. B. L. Laube, D. L. Swift, H. N. Wagner, Jr., P. S. Norman, and G. K. Adams III, Am. Rev. Resp. Dis., 133, 740-743 (1986).
25. A. K. Simonds, S. P. Newman, M. A. Johnson, N. Talaee, C. A. Lee, and S. W. Clarke, Am. Rev. Resp. Dis., 141, 827-829 (1990).