The transport of the anti-HIV drug, 2',3'-didehydro-3'deoxythymidine (D4T), across the blood-brain and blood-cerebrospinal fluid barriers

British Journal of Pharmacology

Volumn 125, Issue 1, 1998, Pages 49-54

  Thomas, Sarah A ^a   Segal, Malcolm B ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Blood brain barrier; Blood CSF barrier; Brain; Choroid plexus; CSF; D4T; HIV; Stavudine; Transport

Indexed keywords

ANTIVIRUS AGENT; CARBON 14; MANNITOL; STAVUDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BLOOD CEREBROSPINAL FLUID BARRIER; BRAIN PERFUSION; CHOROID PLEXUS; CONTROLLED STUDY; DRUG CEREBROSPINAL FLUID LEVEL; DRUG TRANSPORT; GUINEA PIG; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIPOPHILICITY; NONHUMAN; PERMEABILITY; PRIORITY JOURNAL; VIRUS REPLICATION;

ANALYSIS OF VARIANCE; ANIMALS; ANTI-HIV AGENTS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BRAIN; GUINEA PIGS; REVERSE TRANSCRIPTASE INHIBITORS; STAVUDINE; THYMIDINE; ZIDOVUDINE;

EID: 0031657903     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702044     Document Type: Article

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