Overview of the preparation, use and biological studies on polyglycerol polyricinoleate (PGPR)

Food and Chemical Toxicology

Volumn 36, Issue 9-10, 1998, Pages 711-718

  Wilson, R ^a   Van Schie, B J ^b   Howes, D ^a  

^a UNILEVER RESEARCH   (United Kingdom)

^b Givaudan SA   (Switzerland)

Author keywords

E476; Food emulsifier; PGPR; Polyesters; Polyglycerol; Polyglycerol polyricinoleate; Polyricinoleic acid; Safety assessment

Indexed keywords

EMULSIFYING AGENT; FOOD ADDITIVE; GLYCEROL DERIVATIVE; POLYESTER;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ARTICLE; CARCINOGENICITY; CHICKEN; CHRONIC TOXICITY; DRUG SAFETY; FEMALE; FOOD SAFETY; HUMAN; HUMAN EXPERIMENT; LIPID METABOLISM; MALE; NONHUMAN; NORMAL HUMAN; RAT; REPRODUCTIVE TOXICITY; RISK ASSESSMENT; XENOBIOTIC METABOLISM;

ANIMALS; CACAO; CARCINOGENICITY TESTS; FOOD ADDITIVES; GLYCEROL; HUMANS; NO-OBSERVED-ADVERSE-EFFECT LEVEL; RICINOLEIC ACIDS; TOXICITY TESTS;

ANIMALIA; GALLUS GALLUS; RODENTIA;

EID: 0031656825     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(98)00057-X     Document Type: Article

References (10)

1. Banford H. F., Gardiner K. J., Howat G. R. and Thomson A. F. (1970) The use of polyglycerol polyricinoleate in chocolate. Confectionery Production 36, 359-365.
2. FAC (1992) Food Advisory Committee Report on the Review of The Emulsifiers and Stabilisers in Food Regulations. pp. 1-71. FdAC/REP/11, HMSO 1992.
3. FAO (1992) Compendium of food additive specifications: Vol. 2. Polyglycerol esters of interesterified ricinolic acid. pp. 1119-1120. FAO Food and Nutrition Paper 52/2. Rome, 1992.
4. Howes D., Wilson R. and James C. T. (1998) The fate of ingested glyceran esters of condensed castor oil fatty acids [polyglycerol polyricinoleate (PGPR)] in the rat. Food and Chemical Toxicology 36, 719-738.
5. JECFA (1974) 17th Report of the Joint FAO/WHO Expert Committee on Food Additives. Wld Hlth Org. Tech. Rep. Ser. 1974, No. 539.
6. Philp J. McL. (1981) Evaluation of the safety of foods. Proceedings of the Nutrition Society 40, 47-56.
7. Smith M. R., Wilson R. and Hepburn P. A. (1998) Assessment of the carcinogenic potential of polyglycerol polyricinoleate in rats and mice. Food and Chemical Toxicology 36, 747-754.
8. Wilson R., Doell B. H., Groger W., Hope J. and Gellatly J. B. M. (1970) The physiology of liver enlargement. In Metabolic Aspects of Food Safety, ed. F. J. C. Roe, Chapter 15, 363-418. Blackwell, Oxford.
9. Wilson R. and Smith M. (1998a) A three-generation reproduction study on polyglycerol polyricinoleate (PGPR) in Wistar rats. Food and Chemical Toxicology 36, 739-741.
10. Wilson R. and Smith M. (1998b) Human studies on polyglycerol polyricinoleate (PGPR). Food and Chemical Toxicology 36, 743-745.