Comparison of iodotyrosines and methionine uptake in a rat glioma model

Journal of Nuclear Medicine

Volumn 39, Issue 9, 1998, Pages 1596-1599

  Langen, Karl Josef ^a   Clauss, Ralf P ^b   Holschbach, Marcus ^b   Mühlensiepen, Heinz ^b   Kiwit, Jürgen C W ^b   Zilles, Karl ^b   Coenen, Heinz H ^b   Müller Gärtner, Hans W ^b  

^a FORSCHUNGSZENTRUM JÜLICH   (Germany)

^b NONE

Author keywords

3 (123 125I) iodo O methyl methyl L tyrosine; 3 123I iodo methyl L tyrosine; methyl 3H L methio nine; Amino acids; Autoradiography; Cerebral glioma

Indexed keywords

3 IODO O METHYL ALPHA METHYLTYROSINE I 123; 3 IODO O METHYL ALPHA METHYLTYROSINE I 125; 3 IODOMETIROSINE I 123; ALPHA METHYLMETHIONINE H 3; IODOTYROSINE; METHIONINE; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BASAL GANGLION; CONTROLLED STUDY; GLIOMA; MALE; NONHUMAN; PRIORITY JOURNAL; RADIOISOTOPE DISTRIBUTION; RAT;

ANIMALS; BRAIN; BRAIN NEOPLASMS; GLIOMA; IODINE RADIOISOTOPES; MALE; METHIONINE; METHYLTYROSINES; NEOPLASM TRANSPLANTATION; RATS; RATS, INBRED F344; TRITIUM;

EID: 0031656135     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Derlon JM, Boudet C, Bustany P, et al. Carbon-11-L-methionine uptake in gliomas. Neurosurgery 1989;25:720-728.
2. Ogawa T, Shishido F, Kanno I, et al. Cerebral glioma: evaluation with methionine PET. Radiology 1993;186:45-53.
3. 11C-methionine. J Comput Assist Tomogr 1983;7:1062-1066.
4. Mosskin M, Ericson K, Hindmarsh T, et al. PET compared with MRI and CT in supratentorial gliomas using multiple stereotactic biopsies as reference. Acta Radiol 1989;30:225-323.
5. 123I]iodo-α-methyl-tyrosine and SPECT. J Nucl Med 1989;30:110-112.
6. 124IMT and first clinical results. J Nucl Med 1990;31:281-286.
7. 123I]iodo-α-methyl-tyrosine: competition with natural L-amino acids. J Nucl Med 1991;32:1225-1228.
8. Kawai K, Fujibayashi Y, Saji H, et al. A strategy for the study of cerebral amino acid transport using iodine-123-labeled amino acid radiopharmaceutical: 3-iodo-α-methyl-L-tyrosine. J Nucl Med 1991;32:819-824.
9. Schober O, Meyer G-J, Stolke D, Hundeshagen H. Brain tumor imaging using C-11-labeled L-methionine and D-methionme. J Nucl Med 1985;26:98-99.
10. 18F]fluoro-tyrosine. J Nucl Med 1991;32:1338-1346.
11. 18F]fluoro-iyrosine: a new PET tracer of protein synthesis. J Nucl Med 1989;30:1367-1372.
12. 123I-α-methyl-tyrosine in Hirntumor-Rezidiven. Nuklearmedizin 1995;34:71-75.
13. Kuwert T, Morgenroth C, Woesler B, et al. Uptake of iodine-123-α-methyl-tyrosine by gliomas and non-neoplastic brain lesions. Eur J Nucl Med 1996;23:1345-1353.
14. Schmidt D, Wunderlich G, Langen K-J, et al. Iodine-123-α-methyl-tyrosine (IMT) SPECT for evaluation of chemotherapy in cerebral gliomas [Abstract]. J Nucl Med 1996;37:354P.
15. 11C]-L-methionine uptake in cerebral gliomas: a comparative study using SPECT and PET. J Nucl Med 1997;38:517-522.
16. Krummeich C, Holschbach M, Stöcklin G. Direct n.c.a. electrophilic radioiodination of tyrosine analogues; their in vivo stability and brain uptake in mice. Appl Radiat Isot 1994;45:929-935.
17. 123I]iodo-α-methyl-tyrosine. Eur J Nucl Med 1997;24:1162-1166.
18. Ishiwata K, Kubota K, Murakami M, et al. Reevaluation of amino acid PET studies: can the protein synthesis rates in brain and tumor tissues be measured in vivo? J Nucl Med 1993;34:1936-1943.
19. Bergström M, Ericson K, Hagenfeldt L, et al. PET study of methionine accumulation in glioma and normal brain tissue: competition with branched chain amino acids. J Comput Assist Tomogr 1987;11:208-213.