Comparison of a topical benzoyl peroxide gel, oral minocycline, oral doxycycline and a combination for suppression of P. acnes in acne patients

Journal of Dermatological Treatment

Volumn 9, Issue 3, 1998, Pages 187-191

  Kligman, A M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Acne; Benzoyl peroxide; Doxycycline; Minocycline D; Propionibacterium acnes

Indexed keywords

BENZOYL PEROXIDE; DOXYCYCLINE; MINOCYCLINE; TETRACYCLINE; TRIAZ; UNCLASSIFIED DRUG;

ACNE; ADOLESCENT; ADULT; ARTICLE; BACTERIOLOGY; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; HUMAN; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROPIONIBACTERIUM ACNES; STATISTICAL ANALYSIS; TOPICAL DRUG ADMINISTRATION;

EID: 0031656110     PISSN: 09546634     EISSN: None     Source Type: Journal    
DOI: 10.3109/09546639809160552     Document Type: Article

References (34)

1. Eady EA, Jones CE, Gardner KJ et al. Tetracycline-resistant Propionibacteria from acne patients are cross resistant to doxycycline but sensitive to minocycline. Br J Dermatol (1993) 128: 556.
2. Rossman RE, Minocycline treatment of tetracycline resistance and tetracycline responsive acne vulgaris. Cutis (1981) 27: 196.
3. Epstein ME, Amodio-Groton M, Salick NS, Anti-microbial agents for the dermatologist. J Am Acad Dermatol (1997) 37: 365.
4. Leyden JJ, Kaidbey KH, Gans EH, The antimicrobial effects in vivo of minocycline, doxycycline and tetracycline in humans. J Dermatol Treat (1996) 7: 223.
5. Leyden JJ, Gans EH, Evaluation of the antimicrobial effects in vivo of Triaz® Gel (benzoyl peroxide special gel). Cleocin T Lotion (clindamycin phosphate lotion) and Azelex® Cream (azelaic acid) in humans. J Dermatol Treat (1997) 8 (Suppl 2): 57.
6. Leyden JJ, Gans E, The human in vivo antimicrobial effects of dual acne therapy: oral Dynacin® (minocycline HCl), plus topical Triaz® (benzoyl peroxide special gel). J Dermatol Treat (1997) 8 (Suppl 2): 53.
7. Plewig G, Schopf E, Anti-inflammatory effects of antibacterial agents: an in vivo study. J Invest Dermatol (1975) 65: 532.
8. Elewski BE, Lamb BAJ, Sams W, In vivo suppression of neutrophil chemotaxis by systematically and topically administered tetracycline. J Am Acad Dermatol (1983) 8: 807.
9. Webster GF, Toso SM, Hagemann F, Inhibition of a model of in vitro granuloma formation by tetracyclines and ciprofloxacin. Arch Dermatol (1994) 130: 748.
10. Golub LM, Ramamurthy EC, McNamara L et al. Tetracyclines inhibit tissue collagenase activity. J Peridont Res (1985) 20: 12.
11. VanBaar HMJ, Kerkhof VD, Mies PD et al, Tetracyclines are potent scavengers of the superoxide radical. Br J Dermatol (1987) 117: 131.
12. Banck G, Forsgren D, Antibiotics and suppression of lymphocyte function in vitro. Antimicrob Agents Chemother (1979) 16: 554.
13. Thung YH, Ferrante A, Inhibition of mitogen-induced human lymphocyte proliferative responses by tetracycline analogues. Clin Exp Dermatol (1987) 35: 443.
14. Beard NS, Armentrout SA, Weisberger AS. Inhibition of mammalian protein synthesis by antibiotics. Pharmacol Rev (1969) 21: 213.
15. Pato ML, Tetracycline inhibits propagation of DNA replication and alters membrane properties. Antimicrob Agents Chemother (1977) 11: 318.
16. Forsgren A, Gnarpe H, Tetracycline interference with the bactericidal effect of serum. Nature New Biol (1973) 244: 82.
17. Katcyama I, Yokozeki H, Nishioka K, Oral minocycline improved keratosis follicularis squamosa and related disorder. J Dermatol (1994) 21: 604.
18. Celerier P, Latoux D, Dreno B, In vitro modulation of epidermal inflammatory cytokines by minocycline. Arch Dermatol Res (1990) 288: 421.
19. Marks R, Ellis J, Comparative effectiveness of tetracycline and ampicillin in rosacea. A controlled trial. Lancet (1971) 2: 1049.
20. Urabe H, Koda H, Perioral dermatitis and rosacea-like dermatitis. Dermatologica (1976) 152 (Suppl 1): 155.
21. Davins MC, Pyoderma gangrenosum. Successful treatment with minocycline. Clin Exp Dermatol (1981) 6: 219.
22. Diamphongsant T, Tetracycline for the treatment of pityriasis lichenoides. Br J Dermatol (1974) 91: 319.
23. Angele-Besson C, Koeppel MC, Confluent and reticulated papillomatosis treated with tetracyclines. Int J Dermatol (1995) 34: 567.
24. Poskitt L, Wilkinson JD, Clearance of confluent reticulated papillomatosis of Gougerot and Carteaud with minocycline. Br J Dermatol (1993) 129: 351.
25. Shelley WB, Essential progressive telangiectasia: successful treatment with tetracycline. J Am Acad Dermatol (1971) 216: 1343.
26. Thomas I, Khorenian S, Arbusfeld DM, Treatment of generalized bullous pemphigoid with oral tetracycline. J Am Acad Dermatol (1993) 28: 74.
27. Pereyo NG, Davis LS, Generalized bullous pemphigoid controlled by tetracycline therapy alone. J Am Dermatol (1995) 32: 138.
28. Poskitt L, Wojnarowska F, Minimizing cicatrical pemphigoid orodynia with minocycline. Br J Dermatol (1995) 132: 784.
29. Thomsen K, Osterbye P, Pustolosis palmaris et plantaris. Br J Dermatol (1973) 89: 293.
30. Humbert P, Traffel P, Buchet S et al, The tetracyclines in dermatology. J Am Acad Dermatol (1991) 25: 691.
31. Prulus HE, minocycline treatment of rheumatoid arthritis. Ann Intern Med (1995) 122: 147 (editorial).
32. Cunliffe WJ, Forster RA, Greenwood ND et al, Tetracycline in acne vulgaris: a clinical and laboratory investigation. BMJ (1973) 4: 332.
33. Shapiro LE, Knowles SR, Shear NH, Comparative safety of tetracycline, minocycline and doxycycline. Arch Dermatol (1997) 133: 1224.
34. Gouldin V, Glass, D, Cunliffe WJ, Safety of long-term high-dose minocycline in the treatment of acne. Br J Dermatol (1996) 134: 693.