Genotypic and phenotypic characterization of Cryptosporidium parvum isolates from people with AIDS

Journal of Infectious Diseases

Volumn 178, Issue 3, 1998, Pages 834-840

  Widmer, G ^b   Tzipori, S ^a   Fichtenbaum, C J ^b   Griffiths, J K ^b  

^a TUFTS UNIVERSITY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CATTLE; CELL STRAIN CACO 2; CLINICAL ARTICLE; CONTROLLED STUDY; CRYPTOSPORIDIUM PARVUM; GENETIC HETEROGENEITY; GENOTYPE; HUMAN; HUMAN CELL; MONOLAYER CULTURE; MOUSE; NEWBORN; NONHUMAN; OOCYST; PARASITE IDENTIFICATION; PARASITE ISOLATION; PARASITE VIRULENCE; PHENOTYPE; PRIORITY JOURNAL; SPOROZOITE;

EID: 0031654575     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/515373     Document Type: Article

References (23)

1. Tzipori S. Cryptosporidiosis in perspective. Adv Parasitol 1988; 27: 63-130.
2. Petersen C. Cryptosporidiosis in patients infected with the human immuno-deficiency virus. Clin Infect Dis 1992; 15:903-9.
3. Guerrant RL. Cryptosporidiosis: an emerging, highly infectious threat. Emerg Infect Dis 1997;3:51-7.
4. Griffiths JK. Human cryptosporidiosis: epidemiology, transmission, clinical disease, treatment, and diagnosis. Adv Parasitol 1998;40:38-87.
5. Chacin-Bonilla L. Criptosporidiosis en humanos. Rev Invest Clin 1995; 36:207-50.
6. Blanshard C, Jackson AM, Shanson DC, Francis N, Gazzard BG. Cryptosporidiosis in HIV-seropositive patients. Q J Med 1992;85:813-23.
7. Pedersen C, Danner S, Lazzarin A, et al. Epidemiology of cryptosporidiosis among European AIDS patients. Genitourin Med 1996; 72:128-31.
8. McKenzie WR, Hoxie NJ, Proctor ME, et al. A massive outbreak in Milwaukee of Cryptosporidium infection transmitted through the public water supply. N Engl J Med 1994;331:161-7.
9. Solo-Gabriele H, Neumeister S. US outbreaks of cryptosporidiosis. J Am Waterworks Assoc 1996; 88:76-86.
10. Bonnin A, Fourmaux MN, Dubremetz JF, et al. Genotyping human and bovine isolates of Cryptosporidium parvum by polymerase chain reaction-restriction fragment length polymorphism analysis of a repetitive DNA sequence. FEMS Microbiol Lett 1996; 137:207-11.
11. Carraway M, Tzipori S, Widmer G. Identification of genetic heterogeneity in the Cryptosporidium parvum ribosomal repeat. Appl Environ Microbiol 1996;62:712-6.
12. Carraway M, Tzipori S, Widmer G. New RFLP marker in Cryptosporidium parvum identifies mixed parasite populations and genotypic instability in response to host change. Infect Immun 1997;65:3958-60.
13. Peng MM, Xiao L, Freeman AR, et al. Genetic polymorphism among Cryptosporidium parvum isolates: evidence for two distinct human transmission cycles. Emerg Infect Dis 1997;3:567-73.
14. Griffiths JK, Moore R, Dooley S, Keusch GT, Tzipori S. Cryptosporidium parvum infection of Caco-2 monolayers induces an apical monolayer defect, selectively increases transmonolayer permeability, and causes epithelial cell death. Infect Immun 1994;62:4506-14.
15. Tzipori S, Rand W, Griffiths J, Widmer G, Crabb J. Evaluation of an animal model system for cryptosporidiosis: therapeutic efficacy of paromomycin and hyperimmune bovine colostrum-immunoglobulin. Clin Diagn Lab Immunol 1994; 1:450-63.
16. Spano F, Putignani L, McLaughlin J, Casemore DP, Crisanti A. PCR-RFLP analysis of the Cryptosporidium oocyst wall protein (COWP) gene discriminates between C. wrairi and C. parvum, and between C. parvum isolates of human and animal origin. FEMS Microbiol Lett 1997; 152:209-17.
17. Theodos CM, Sullivan KL, Griffiths JK, Tzipori S. Profiles of healing and non-healing Cryptosporidium parvum infection in C57BL/6 mice with functional B and T lymphocytes: the extent of IFN-γ modulation determines the outcome of infection. Infect Immun 1997;65:4761-9.
18. Morgan UM, Constantine CC, O'Donoghue P, Meloni BP, O'Brien PA, Thompson RCA. Molecular characterization of Cryptosporidium isolates from human and other animals using random amplified polymorphic DNA analysis. Am J Trop Med Hyg 1995;52:559-64.
19. Widmer G. Genetic heterogeneity and PCR detection of Cryptosporidium parvum. Adv Parasitol 1998;40:224-41.
20. Vasquez JR, Gooze L, Kim K, Gut J, Petersen C, Nelson RG. Potential antifolate resistance determinants and genotypic variation in the bifunctional dihydrofolate reductase-thymidylate synthase gene from human and bovine isolates of Cryptosporidium parvum. Mol Biochem Parasitol 1996;79:153-65.
21. Adams ROB, Guerrant RL, Zu S, Fang G, Roche JK. Cryptosporidium parvum infection of intestinal epithelium: morphological and functional studies in an in vitro model. J Infect Dis 1994; 169:170-7.
22. Finlay BB, Falkow S. Salmonella interactions with polarized human intestinal Caco-2 epithelial cells. J Infect Dis 1990; 162:1096-106.
23. Madara JL. Maintenance of the macromolecular barrier at cell extrusion sites in intestinal epithelium: physiological rearrangement of tight junctions. J Membrane Biol 1990; 116:177-84.