Structure-activity analysis of C-terminal endothelin analogues

Journal of Cardiovascular Pharmacology

Volumn 31, Issue SUPPL. 1, 1998, Pages

  Rovero, P ^a   Galoppini, C ^a   Laricchia Robbio, L ^a   Mazzoni, M R ^b   Revoltella, R P ^a  

^a CNR   (Italy)

^b UNIVERSITY OF PISA   (Italy)

Author keywords

BIA technology; C terminal ET analogues; Endothelin; RIA; Synthetic peptides

Indexed keywords

DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; ENDOTHELIN; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; ENDOTHELIN RECEPTOR; LIGAND; MONOCLONAL ANTIBODY; PEPTIDE FRAGMENT;

ANIMAL; ARTICLE; BINDING COMPETITION; CATTLE; CHEMISTRY; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; METABOLISM; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIBODIES, MONOCLONAL; BINDING, COMPETITIVE; CATTLE; ENDOTHELINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INDICATORS AND REAGENTS; LIGANDS; PEPTIDE FRAGMENTS; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031638092     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199800001-00071     Document Type: Article

References (18)

1. Yanagisawa M, Kurihara H, Kimura S, et al. Endothelin: a potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988;322:411-5.
2. Hunt JT, Lee VG, Stein PD, et al. Structure-activity relationship of monocyclic endothelin analogs. Biorganic R Med Chem Lett 1991; 1:33-8.
3. Rubanyi GM, Polokoff MA. Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology. Pharmacol Rev 1994;46:325-415.
4. Masaki T, Yanagisawa M, Goto K. Physiology and pharmacology of endothelins. Med Res Rev 1992;12:391-421.
5. Sedo A, Vanickova Z. Endothelins as cell growth regulators. Folia Biol 1996;42:79-82.
6. Fukui M, Nakamura T, Ebihara I, et al. Gene expression for endothelins and their receptors in glomeruli of diabetic rats. J Lab Clin Med 1993;122:149-56.
7. Nelson JB, Chan-Tack K, Hedican SP, et al. Endothelin-1 production and decreased endothelin-B receptor expression in advanced prostate cancer. Cancer Res 1996;56:663-8.
8. Laricchia Robbio L, Moscato S, Guidi A, Vigano S, Rovero P, Revoltella RP. Detection and epitope mapping of immunoreactive human endothelin-1 using ELISA and a surface plasmon resonance-based biosensor. Biosensors Bioelectron 1997;12:765-78.
9. Hirata Y, Yanagisawa M, Ohkubo S, et al. Cloning and sequence analysis of cDNA encoding the precursor of a human endothelin-derived vasoconstrictor peptide endothelin: identity of human and porcine endothelin. FEBS Lett 1988;231:440-4.
10. Arai K, Koshi T, Ehara Y, et al. Characterization of immunoreactive endothelin in human urine. Biochem Biophys Res Commun 1992;182:1506-13.
11. Liedberg B, Lundström I, Stenberg E. Principles of biosensing with an extended coupling matrix and surface plasmon resonance. Sensor Actuators [B] 1993;11:63-72.
12. Löfås S, Jonsson B. A novel hydrogel matrix on gold surfaces in surface plasmon resonance sensors for fast and efficient covalent immobilization of ligands. J Chem Soc Commun 1992;1526-8.
13. Jonsson B, Löfås S, Lindquist G. Immobilization of proteins to carboxy methyl dextran-modified gold surface for biospecific analysis in surface plasmon resonance sensors. Anal Biochem 1991;198:268-77.
14. Atherton E, Sheppard RC. Solid phase peptide synthesis: a practical approach. Oxford: IRL Press, 1989.
15. Beffy P, Di Bartolo V, Laricchia Robbio L, et al. Small synthetic peptides of human GM-CSF require different conditions for immobilization, epitope density and presentation in ELISA. Fund Clin Immunol 1994;2:53-61.
16. Cassano E, Galoppini C, Giusti L, et al. A structure-activity study of a C-terminal endothelin analogue. Folia Biol (Praha) 1998;44:11-14.
17. Cody WL, He JX, DePue PL, et al. Structure-activity relationships of the potent combined endothelin-A/endothelin-B receptor antagonist Ac-DDip(16)-Leu-Asp-Ile-Ile-Trp(21): development of endothelin-B receptor selective antagonists. J Med Chem 1995;38: 2809-19.
18. Beffy P, Rovero P, Di Bartolo V, et al. An immunodominant epitope in a functional domain near the N-terminus of human granulocyte-macrophage colony-stimulating factor identified by cross-reaction of synthetic peptides with neutralizing anti-protein and anti-peptide antibodies. Hybridoma 1994;13:457-68.