A proposed bioactive conformation of Peptide T

Journal of Computer-Aided Molecular Design

Volumn 12, Issue 1, 1998, Pages 7-14

  Centeno, Nuria B ^a,b   Perez, Juan J ^a  

^a UNIVERSITAT POLITÈCNICA DE CATALUNYA   (Spain)

^b INST MUNIC D INVESTIGACIO MEDICA   (Spain)

Author keywords

Bioactive conformation; Conformational analysis; Peptide T; Peptide T analogs

Indexed keywords

CONFORMATIONS; SIMULATED ANNEALING;

BIOACTIVE CONFORMATION; CONFORMATIONAL ANALYSIS; CONFORMATIONAL SPACE; EFFECTIVE DIELECTRIC CONSTANTS; GEOMETRICAL CHARACTERISTICS; LOW-ENERGY CONFORMATIONS; PEPTIDE T; PEPTIDE T ANALOGS; POTENT COMPOUNDS; SIDE-CHAINS;

PEPTIDES;

CD4 ANTIGEN; DRUG DERIVATIVE; GLYCOPROTEIN GP 120; PEPTIDE T;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; CONFORMATION; HUMAN; HYDROGEN BOND; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; THERMODYNAMICS;

AMINO ACID SEQUENCE; ANTIGENS, CD4; COMPUTER SIMULATION; HIV ENVELOPE PROTEIN GP120; HUMANS; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PEPTIDE T; PROTEIN STRUCTURE, SECONDARY; THERMODYNAMICS;

EID: 0031638051     PISSN: 0920654X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007994502997     Document Type: Article

References (24)

1. Pert, C.B., Hill, J.M., Ruff, M.R., Berman, R.M., Robey, W.G., Arthur, L.O., Ruscetti, F.W. and Farrar, W.L., Proc. Natl. Acad. Sci. USA, 83 (1986) 9254.
2. Ruff, M.R., Martin, B.M., Ginns, E.I., Farrar, W.L. and Pert, C.B., FEBS Lett., 211 (1987) 17.
3. Wetterberg, L., Alexius, B., Saaf, J., Sonnerborg, A., Britton, S. and Pert, C., Lancet 1, (1987) 159.
4. Farber, E.M., Cohen, E.N., Trozak, D.J. and Wilkinson, D.I., J. Am. Acad. Dermat., 25 (1991) 658.
5. Marastoni, M., Salvadori, S., Baloni, G., Spisani, S., Gavioli, R., Traniello, S. and Tomatis, R., Int. J. Pept. Protein Res., 35 (1990) 81.
6. Rieunier, F., Fulcrand, P., Aumelas, A. and Martinez, J., In Giralt, E. and Andreu, D. (Eds.), Peptides92, ESCOM, 1993, pp. 373-374.
7. Rieunier, F., Ph.D. Thesis, Université Montpellier II, France (1994).
8. Marastoni, M., Salvadori, S., Baloni, G., Scaranari, V., Spisani, S., Reali, E., Giuliani, A.L. and Tomatis, R., Eur. J. Med. Chem., 27 (1992) 383.
9. Marastoni, M., Salvadori, S., Baloni, G., Scaranari, V., Spisani, S., Reali, E., Traniello, S. and Tomatis, R., Int. J. Pept. Protein Res., 41 (1993) 447.
10. Marastoni, M., Salvatori, S., Balboni, G., Spisani, S., Gavioli, R., Traniello, S. and Tomatis, R., Arzneim.-Forsch/Drug Res., 8 (1989) 926.
11. Picone, D., Temussi, P.A., Marastoni, M., Tomatis, R. and Motta, A., FEBS Lett., 231 (1988) 159.
12. Motta, A., Picone, D., Temussi, P.A., Marastoni, M. and Tomatis, R., Biopolymers, 28 (1989) 479.
13. Cotelle, N., Lohez, M., Cotelle, P. and Henichart, J.-P., Biochem. Biophys. Res. Commun., 171 (1990) 596.
14. Chen, J., Barber, A., Pedersen, J., Brant-Rauf, P.W., Carucci, J., Murphy, R.B., Carty, R.P., Licht, D. and Pincus, M.R., J. Protein Chem., 8 (1989) 87.
15. Shah, D., Chen, J.M., Carty, R.P., Pincus, M.R. and Scheraga, H.A., Int. J. Pept. Protein Res., 34 (1989) 235.
16. Andrianov, A.M. and Akhrem, A.A., Mol. Biol., 27 (1993) 576.
17. Pearlman, D.A., Case, D.A., Cadwell, J.C., Seibel, G.L., Singh, U.C., Weiner, P. and Kollman, P.A., AMBER4.0, University of California, San Francisco, CA, 1991.
18. Weiner, S.J., Kollman, P.A., Case, D.A., Singh, U.C., Ghio, C., Alagona, G., Profeta, Jr., S. and Weiner, P., J. Am. Chem. Soc., 106 (1984) 765.
19. Centeno, N.B., Ph.D. Thesis, Universitat Politecnica de Catalunya, Barcelona (1996).
20. Maiorou, V.N. and Crippen, G.M., Proteins, 22 (1995) 273.
21. Filizola, M., Centeno, N.B. and Perez, J.J., J. Pept. Sci., 3 (1997) 85.
22. Nikiforovich, G.V., Int. J. Pept. Protein Res., 44 (1994) 513.
23. Marastoni, M., Salvatori, S., Balboni, G., Spisani, S., Gavioli, R., Traniello, S. and Tomatis, R., In Aubry, A., Marraud, M. and Vitoux, B. (Eds), 'Second Forum on Peptides', John Libbey Eurotext Ltd., Paris, 1989.
24. Llorens, O., Centeno, N.B., Filizola, M., Spisani, S., Marastoni, M., Calafell, M., Herranz, C. and Perez, J.J., Lett. Pept. Sci., in press.