Endothelins inhibit mineralization of rat calvarial osteoblast-like cells

Journal of Cardiovascular Pharmacology

Volumn 31, Issue SUPPL. 1, 1998, Pages

  Hiruma, Yoshiharu ^a   Inoue, Atsuto ^a   Shiohama, Aiko ^a   Otsuka, Eri ^a   Hirose, Shigehisa ^a   Yamaguchi, Akira ^b   Hagiwara, Hiromi ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b SHOWA UNIVERSITY   (Japan)

Author keywords

ETA receptor; Mineralization; Osteoblast

Indexed keywords

CALCIUM; ENDOTHELIN; ENDOTHELIN A RECEPTOR; ENDOTHELIN RECEPTOR;

ANIMAL; ARTICLE; BONE MINERALIZATION; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; METABOLISM; NEWBORN; OSTEOBLAST; RAT; SKULL; WISTAR RAT;

ANIMALS; ANIMALS, NEWBORN; CALCIFICATION, PHYSIOLOGIC; CALCIUM; CELLS, CULTURED; ENDOTHELINS; HUMANS; OSTEOBLASTS; RATS; RATS, WISTAR; RECEPTOR, ENDOTHELIN A; RECEPTORS, ENDOTHELIN; SKULL;

EID: 0031630063     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199800001-00150     Document Type: Article

References (9)

1. Hagiwara H, Inoue A, Yamaguchi A, et al. cGMP produced in response to ANP and CNP regulates proliferation and differentiation of osteoblastic cells. Am J Physiol 1996;270:C1311-8.
2. Inoue A, Hiruma Y, Hirose S, et al. Stimulation by C-type natriuretic peptide of the differentiation of clonal osteoblastic MC3T3-E1 cells. Biochem Biophys Res Commun 1996;221:703-7.
3. Kurihara K, Kurihara H, Suzuki H, et al. Elevated blood pressure, and craniofacial abnormalities in mice deficient in endothelin-1. Nature 1994;368:703-10.
4. A receptor in rat tracheal and xipoid cartilage and in fetal rat epiphysis. Am J Physiol 1995;268:C496-502.
5. Alam ASMT, Gallagher A, Shankar V, et al. Endothelin inhibits osteoclastic bone resorption by a direct effect on cell motility: implications for the vascular control of bone resorption. Endocrinology 1992;130:3617-24.
6. Tatrai A, Foster S, Lakatos P, Shankar G, Stern PH. Endothelin-1 actions on resorption, collagen and noncollagen protein synthesis, and phosphatidylinositol turnover in bone organ cultures. Endocrinology 1992;131:603-7.
7. Zaidi M, Alam ASMT, Bax BE, et al. Role of the endothelial cell in osteoclast control: new perspectives. Bone 1993;14:97-102.
8. Takuwa Y, Masaki T, Yamashita K. The effects of the endothelin family peptides on cultured osteoblastic cells from rat calvariae. Biochem Biophys Res Commun 1990;170:998-1005.
9. 2+ from extra- and intracellular pools in osteoblastic cells. Am J Physiol 1989;257:E797-803.