Chemoradiotherapy interactions in the central nervous system

Medical and Pediatric Oncology

Volumn 30, Issue SUPPL. 1, 1998, Pages 10-16

  Bleyer, W Archie ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIFOSTINE; ANTINEOPLASTIC AGENT; BROXURIDINE; BUTHIONINE SULFOXIMINE; CISPLATIN; CYTARABINE; DACTINOMYCIN; METHOTREXATE; MISONIDAZOLE; PREDNISOLONE;

BRAIN LEUKEMIA; BRAIN RADIATION; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CONFERENCE PAPER; HUMAN; INTRAPERITONEAL DRUG ADMINISTRATION; INTRATHECAL DRUG ADMINISTRATION; LEUKOENCEPHALOPATHY; NEUROTOXICITY; PRIORITY JOURNAL; RADIOSENSITIZATION; ANIMAL; CANCER INVASION; CENTRAL NERVOUS SYSTEM; DRUG EFFECT; DRUG THERAPY; MULTIMODALITY CANCER THERAPY; PATHOLOGY; RADIATION EXPOSURE; RADIOTHERAPY; REVIEW;

ANIMALS; CENTRAL NERVOUS SYSTEM; COMBINED MODALITY THERAPY; DRUG THERAPY; HUMANS; LEUKEMIC INFILTRATION; RADIOTHERAPY;

EID: 0031615111     PISSN: 00981532     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1096-911x(1998)30:1+<10::aid-mpo2>3.3.co;2-n     Document Type: Article

References (20)

1. Bleyer WA, Griffin TW: White matter necrosis, mineralizing microangiopathy, and intellectual abilities in survivors of childhood leukemia: Associations with central nervous system irradiation and methotrexate therapy. In Gilbert HA, Kagen AR (eds): "Radiation Damage to the Nervous System." New York: Raven Press, 1980, pp. 115-174.
2. Aur RJA, Simone JV, Versoza MS, et al.: Leucoencefalopatia en ninos con leucemia linfocitica aguda sometido a terapeutica preventiva del sistema nervioso central. Sangre (Barcelona) 23:1-12, 1978.
3. Bleyer WA: Radiotherapy versus intrathecal chemotherapy for CNS prophylaxis in childhood ALL: Article revisited. Oncology 3:59-69, 1889a.
4. Bleyer WA, Poplack DG: Prophylaxis and treatment of leukemia in the central nervous system and other sanctuaries. Semin Oncol 12:131-148, 1985.
5. Bleyer A: CNS chemoradiotherapy of childhood leukemia: The plot thickens but the ending bodes well. J Clin Oncol 13:2480-2481, 1995.
6. Sokol GH, Maickel RP (eds): "Radiation-Drug Interactions in the Treatment of Cancer." New York: John Wiley & Sons, Inc., 1980.
7. Van der Kogel AJ, Sissingh HA: Effects of methotrexate and cytosine arabinoside on the radiation tolerance of the rat spinal cord. Radiother Oncol 4:239-251, 1985.
8. Margileth D, Poplack DG, Pizzo PA, et al.: Blindness during remission in two patients with acute lymphoblastic leukemia: A possible complication of multimodality therapy. Cancer 39:58-61, 1977.
9. Littman P, Rosenstock JG, Bailey C: Radiation myelitis following craniospinal irradiation with concurrent actinomycin-D therapy. Med Pediatr Oncol 5:145-151, 1978.
10. Taylor EM, Geyer JR, Milstein JM, et al.: A rodent model of chemoradiotherapy-induced white matter necrosis. NCI Mongr 6:59-64, 1988.
11. Geyer JR, Taylor EM, Milstein JM, et al.: Radiation, methotrexate and white matter necrosis. Laboratory evidence for neural radioprotection with pre-radiation methotrexate. Int J Radiat Oncol Biol Phys 15:373-375, 1988.
12. Mullenix PJ, Kernan WJ, Schunior A, et al.: Interactions of steroid, methotrexate, and radiation determine neurotoxicity in an animal model to study therapy for childhood leukemia. Pediatr Res 35:171-178, 1994.
13. Balsom WR, Bleyer WA, Robison LL, et al.: Intellectual function in long-term survivors of childhood acute lymphoblastic leukemia: Protective effect of pre-irradiation methotrexate? A Children's Cancer Group Study. Med Pediatr Oncol 19:486-492, 1991.
14. Spence AM, Krohn KA, Edmonson SW, et al.: Radioprotection in rat spinal cord with WR-2721 following cerebral lateral intraventricular injection. Int J Radiat Oncol Biol Phys 12:1479-1482, 1986.
15. Spence AM, Edmonson SW, Krohn KA, et al.: Toxicity and biodistribution of the radioprotectors, WR2721, MR77913, and WR3689, in the CNS following intraventricular administration. Int J Radiat Oncol Biol Phys 12:1653-1660, 1986.
16. Spence AM, Krohn KA, Edmonson SW, et al.: WR-2721, WR-77913 and WR-3689 radioprotection in the rat spinal cord. Pharmacol Ther 39:89-91, 1988.
17. Alberts D, Bleyer WA: Future development of amifostine in cancer treatment. Semin Oncol 23:90-99, 1996.
18. Griffin TW, Rasey JS, Bleyer WA: The effect of photon irradiation on blood-brain barrier permeability to methotrexate in mice. Cancer 40:1109-1 111, 1977.
19. Morse ME, Savitch JL, Bleyer WA: Altered central-nervous-system pharmacology of methotrexate in childhood leukemia: Another sign of meningeal leukemia. J Clin Oncol 3:19-24, 1985.
20. Geiser CF, Bishop Y, Jaffe N, et al.: Adverse effects of intrathecal methotrexate in children with acute leukemia in remission. Blood 45:189-195, 1975.