A Clinical Trial of Hypertonic Saline Nasal Spray in Subjects with the Common Cold or Rhinosinusitis

Archives of Family Medicine

Volumn 7, Issue 1, 1998, Pages 39-43

  Adam, Patricia ^a   Stiffman, Michael ^a   Blake Jr , Robert L ^b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SODIUM CHLORIDE;

ADULT; ARTICLE; CLINICAL TRIAL; COMMON COLD; FEMALE; HUMAN; INTRANASAL DRUG ADMINISTRATION; MALE; RANDOMIZED CONTROLLED TRIAL; RHINITIS; SINUSITIS; TIME; TREATMENT FAILURE;

ADMINISTRATION, INTRANASAL; ADULT; COMMON COLD; FEMALE; HUMANS; MALE; RHINITIS; SALINE SOLUTION, HYPERTONIC; SINUSITIS; TIME FACTORS; TREATMENT FAILURE;

EID: 0031613766     PISSN: 10633987     EISSN: None     Source Type: Journal    
DOI: 10.1001/archfami.7.1.39     Document Type: Article

References (20)

1. Principal diagnosis and ICD-9-CM Code. Vital Health Stat. 1993-1994;series 13: 114-116.
2. National Disease and Therapeutic Index. Plymouth Meeting, Pa: IMS Inc; 1989:487.
3. Holleman DR, Williams JW, Simel DL. Usual care and outcomes in patients with sinus complaints and normal results of sinus roentgenography. Arch Fam Med. 1995;4:246-251.
4. Smith MBH, Feldman W. Over-the-counter cold medications. JAMA. 1995;269: 2258-2263.
5. Sperber SJ, Sorrentino JV, Riker DK, Hayden FG. Evaluation of an alpha agonist alone and in combination with a nonsteroidal antiinflammatory agent in the treatment of experimental rhinovirus colds. Bull N Y Acad Med. 1989;65:145-160.
6. Darmansjah I, Akib T, Setiawati A, Muchtar A, Rifki N. A dose-ranging study of phenylpropanolamine on nasal airflow. Int J Clin Pharmacol Ther Toxicol. 1990; 28:282-285.
7. Akerlund A, Klint T, Olen L, Rundcrantz H. Nasal decongestant effect of oxymetazoline in the common cold: an objective dose-response study in 106 patients. J Laryngol Otol. 1989;103:743-746.
8. Riker DK, Hendley JO, Doyle WJ, et al. Therapeutic effects of an anticholinergic-sympathomimetic combination in induced rhinovirus colds. Ann Otol Rhinol Laryngol. 1993;102:521-527.
9. Doyle JF, McBride TP, Skoner MP, Maddern BR, Swaltney JM, Uhrin M. A double-blind, placebo-controlled clinical trial of the effect of chlorpheniramine on the response of the nasal airway, middle ear and eustachian tube to provocative rhinovirus challenge. Pediatr Infect Dis J. 1988;7:229-238.
10. Howard JC, Kantner TR, Litienfield LS, et al. Effectiveness of antihistamines in the symptomatic management of the common cold. JAMA 1979;242:2414-2417.
11. Hayden FG, Diamond L, Wood PB, Korts DC, Wecker MT. Effectiveness and safety of intranasal ipratropium bromide in common colds. Ann Intern Med. 1996;125: 89-97.
12. Meltzer EO, Orgel HA, Backhaus JW, et al. Intranasal flunisolide spray as an adjunct to oral antibiotic therapy for sinusitis. J Allergy Clin Immunol. 1993;92:812-823.
13. Druce HM. Adjuncts to medical management of sinusitis. 1990;103:880-883.
14. Slavin RG. Management of sinusitis. J Am Geriatr Soc. 1991;39:212-217.
15. Mossad SB, Macknin ML, Medendorp SV, Mason P. Zinc gluconate lozenges for treating the common cold. Ann Intern Med. 1996;125:81-88.
16. Talbot AR, Herr TM, Parsons DS. Mucociliary clearance and buffered hypertonic saline solution. Laryngoscope. 1997;107:500-503.
17. Parsons DS. Chronic sinusitis: a medical or surgical disease? Otolaryngol Clin North Am. 1996;29:1-9.
18. Williams JW, Holleman DR, Samsa GP, Simel DL. Randomized controlled trial of 3 vs 10 days of trimethoprim-sulfamethoxazole for acute maxillary sinusitis. JAMA. 1995;273:1015-1021.
19. Williams JW, Simel DL, Roberts L, Samsa G. Clinical evaluation for sinusitis. Ann Intern Med. 1992;117:705-710.
20. Berg O, Bergstedt H, Lind MG, Carenfelt C, Perols O. Discrimination of purulent from nonpurulent maxillary sinusitis. Ann Otol. 1981;90:272-275.