Mechanism of Inhibition of Rat Liver Bilirubin UDP-Glucuronosyltransferase by Triphenylalkyl Derivatives

Journal of Biochemical and Molecular Toxicology

Volumn 12, Issue 1, 1998, Pages 19-27

  Said, Mourad ^a   Battaglia, Eric ^b   Elass, Abdelaziz ^c   Cano, Virginie ^d   Ziegler, Jean Claude ^d   Cartier, Alain ^e   Livertoux, Marie Hélène ^d   Vergoten, Gérard ^c   Fournel Gigleux, Sylvie ^b   Magdalou, Jacques ^b  

^a FACULTÉ DES SCIENCES   (Morocco)

^b CNRS   (France)

^c INSERM   (France)

^d Centre du Medicament URA CNRS 597   (France)

^e NANCY UNIVERSITÉ   (France)

Author keywords

Bilirubin glucuronidation; Inhibitors; Molecular modeling; UDP glucuronosyltransferase

Indexed keywords

7,7,7 TRIPHENYLHEPTANOIC ACID; 7,7,7-TRIPHENYLHEPTANOIC ACID; BILIRUBIN; BILIRUBIN GLUCURONOSIDE GLUCURONOSYLTRANSFERASE; ENZYME INHIBITOR; GLUCURONOSYLTRANSFERASE; HEPTANOIC ACID DERIVATIVE;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; LIVER; MALE; PH; RAT; WISTAR RAT;

ANIMALS; BILIRUBIN; ENZYME INHIBITORS; GLUCURONOSYLTRANSFERASE; HEPTANOIC ACIDS; HYDROGEN-ION CONCENTRATION; LIVER; MALE; MODELS, MOLECULAR; RATS; RATS, WISTAR;

EID: 0031606456     PISSN: 10956670     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-0461(1998)12:1<19::AID-JBT4>3.0.CO;2-S     Document Type: Article

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