A Double-Blind, Multicenter Clinical Trial Comparing Efficacy of Once-Daily Metronidazole 1 Percent Cream to Vehicle in Patients with Rosacea

Cutis

Volumn 61, Issue 1, 1998, Pages 44-47

  Breneman, Debra L ^b   Stewart, Daniel ^b   Hevia, Oscar ^b   Hino, Peter D ^b   Drake, Lynn A ^b   Levy, ^a  

^a Dermik Laboratories Inc   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; METRONIDAZOLE;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; MALE; MIDDLE AGED; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL; ROSACEA; TOPICAL DRUG ADMINISTRATION; TREATMENT OUTCOME;

ADMINISTRATION, TOPICAL; ADULT; AGED; AGED, 80 AND OVER; ANTI-INFLAMMATORY AGENTS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; METRONIDAZOLE; MIDDLE AGED; ROSACEA; TREATMENT OUTCOME;

EID: 0031605957     PISSN: 00114162     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Plewig G, Kligman AM: Acne and Rosacea. Berlin, Springer-Verlag, pp 433-435, 1993.
2. Miyachi Y, Imamura S, Niwa Y: Anti-oxidant action of metronidazole: a possible mechanism of action in rosacea. Br J Dermatol 114: 231-234, 1986.
3. Persi A, Rebora A: Metronidazole and Dermodex folliculorum. Acta Derm Venereol 61: 182-183, 1981.
4. Plewig G, Kligman AM: Acne and Rosacea. Berlin, Springer-Verlag, pp 434-435, 1993.
5. Jorizzo JL, Lebwohl MG, Tobey RE: A double-blind, multi-center clinical trial comparing the efficacy of metronidazole 1% cream QD to metronidazole 1% cream BID and their vehicles for 10 weeks in treating rosacea. Submitted for publication.
6. Gamborg Nielson P: Treatment of rosacea with 1% metronidazole cream. A double-blind study. Br J Dermatol 108: 327-332, 1983.
7. Gamborg Nielson P: A double-blind study of 1% metronidazole cream versus systemic oxytetracycline therapy for rosacea. Br J Dermatol 109: 63-65, 1983.