Holt-Oram syndrome and multiple ventricular septal defects: An association suggesting a possible genetic marker?

Cardiology in the Young

Volumn 8, Issue 1, 1998, Pages 128-130

  Bennhagen, Rolf G ^a   Menahem, Samuel ^a  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

Author keywords

Holt Oram syndrome; Multiple ventricular septal defects

Indexed keywords

ADULT; ARM; ARTICLE; CASE REPORT; CONGENITAL MALFORMATION; FEMALE; GENETIC MARKER; GENETICS; HEART SEPTUM DEFECT; HUMAN; INFANT; MALE; SYNDROME;

ADULT; ARM; FEMALE; GENETIC MARKERS; HEART SEPTAL DEFECTS, VENTRICULAR; HUMANS; INFANT; MALE; SYNDROME;

EID: 0031604392     PISSN: 10479511     EISSN: None     Source Type: Journal    
DOI: 10.1017/s1047951100004789     Document Type: Article

References (6)

1. Holt M, Oram S. Familial heart disease with skeletal malformations. Br Heart J 1960;22:236.
2. Terrett JA, Newbury-Ecob R, Cross GS, Fenton I, Raeburn JA, Young ID, Brook JD. Holt-Oram syndrome is a genetically heterogeneous disease with one locus mapping to human chromosome 12q. Nat Genet 1994;6:401-404.
3. Basson CT, Cowley GS, Solomon SD, Weissman B, Poznanski AK, Traill TA, Seidman JG, Seideman CE. The clinical and genetic spectrum of the Holt-Oram syndrome (heart-hand syndrome). N Engl J Med 1994;330:1627.
4. Bonnet D, Pelet A, Legeai-Mallet L, Sidi D, Mathieu M, Parent P, Plauchu H, Serville F, Schinzel A, Weissenbach J et al. A gene for Holt-Oram syndrome maps to the distal long arm chromosome 12. Nat Genet 1994;6:405-408.
5. Terret JA, Newbury-Ecob R, Cross GS, Fenton I, Raeburn JA, Young ID, Brook JD. Holt-Oram syndrome is genetically heterogenous disease with one locus mapping to human chromosome 12q. Nat Genet 1994;6:401-404.
6. Serraf A, Lacour-Gayet F, Bruniaux J, Ouaknine R, Losay J, Petit J, Binet JP, Planche C. Surgical management of isolated multiple ventricular septal defects. Logical approach in 130 cases. J Thorac Cardiovasc Surg 1992;103:437-442.