An increase in endothelial intracellular calcium and F-actin precedes the extravasation of interleukin-2-activated lymphocytes

Microcirculation

Volumn 5, Issue 1, 1998, Pages 71-80

  Ehringer, William D ^a   Edwards, Michael J ^a   Wintergerst, Kupper A ^a   Cox, Abigail ^a   Miller, Frederick N ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Calcium; Endothelial; f actin; IL 2; Lymphocytes; Permeability

Indexed keywords

ACTIN; CALCIUM; FURA 2; INTERLEUKIN 2; PLASMA PROTEIN; SERUM ALBUMIN;

ADULT; ARTICLE; CELL MEMBRANE PERMEABILITY; DRUG EFFECT; HUMAN; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; MALE; METABOLISM; MICROCIRCULATION; VASCULAR ENDOTHELIUM;

ACTINS; ADULT; BLOOD PROTEINS; CALCIUM; CELL MEMBRANE PERMEABILITY; ENDOTHELIUM, VASCULAR; FURA-2; HUMANS; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MALE; MICROCIRCULATION; SERUM ALBUMIN;

EID: 0031604169     PISSN: 10739688     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1549-8719.1998.tb00054.x     Document Type: Article

References (33)

1. Bucana CD, Trial J, Papp AC, Wu KK. (1988). Bovine aortic endothelial cell incubation with interleukin-2: morphological changes correlate with enhanced vascular permeability. Scanning Microsc 2: 1559-1566.
2. Camussi G, Turello E, Bussolino F, Baglioni C. (1991). Tumor necrosis factor alters cytoskeletal organization and barrier function of endothelial cells. Int Arch Allergy Appl Immunol 96:84-91.
3. Damle NK, Doyle LV. (1989). IL-2 activated human killer lymphocytes but not their secreted products mediate increase in albumin flux across cultured endotbclial monolayers. J Immunol 142:2660-2669.
4. Duke SS, King LS, Jones MR, Newman JH, Brigham KL, Forbes JT. (1989). Human recombinant interleukin-2-activated sheep lymphocytes lyse sheep pulmonary microvascular endothelial cells. Cell Immunol 122:188-199.
5. Edwards MJ, Abney DL, Miller FN. (1991). Pentoxifylline inhibits interletikin-2-induced leukocyte-endothelial adherence and reduces systemic toxicity. Surgery 110:199-204.
6. Edwards MJ, Heniford BT, Klar EA, Doak KW, Miller FN. (1992). Pentoxifylline inhibits interlctikin-2-duced toxicity in C57BL/6 mice but preserves antitumor efficacy. J Clin Incest 90:637-641.
7. Ehringer WD, Edwards MJ, Miller FN. (1996). Mechanisms of α-thrombin, bistamine, arid bradykinin induced endothelial permeability. J Cell Physiol 167:562-569.
8. Goeckeler ZM, Wysolmerski RB. (1995). Mysoin light chain kinase-regulated endothelial cell contraction: the relationship between isometric tension, actin polymerization, and mysoin phocphorylation. J Cell Biol 130:613-627.
9. Goldblum SE, Ding X, Campbell-Washington J. (1993). TNF-α induces endothelial F-actin depolymerization, new actin synthesis, and barrier dysfunction. Am J Physiol 264:C894-C905.
10. Goldblum SE, Sun WL. (1990). Tumor necrosis factor-α augments pulmonary arterial transendothelial albumin flux in vitro. Am J Physiol 258:L57-L67.
11. 2+ indicators with greatly improved fluorescent properties. J Biol Chem 260:3440-3450.
12. Ilaverstick DM, Sakai H, Gray LS. (1992). Lymphocyte adhesion can be regulated by cytoskeleton-associated PMA-induced capping of surface receptors. Am J Physiol 262(4 pt 1):C916-C926.
13. Hicks C, Cooley MA, Penny R. (1991). Investigation of interleukin-2 receptors on human endothelial cells. Growth Factors 5:201-208.
14. Huang AJ, Manning JE, Bandak TM, Ratau MC, Hanser KR, Silverstein SC. (1993). Endothelial cell cytosolic free calcium regulates neutrophil migration across monolayers of endothelial cells. J Cell Biol 120: 1371-1380.
15. Kohn EC, Jacobs W, Kim YS, Alessandro R, Stetler-Stevenson WG, Liotta LA. (1994). Calcium influx modulates expression of matrix metalloproteinase-2 (72-kDa Type IV collagenase, gelatinase A). J Biol Chem 269:21505-21511.
16. Kotasek D, Vercellotti GM, Ochoa AO, Bach FH, White JG, Jacob HS. (1988). Mechanism of cultured endothelial injury induced by lymphokine-activated killer cells. Cancer Res 48:5528-5532.
17. 2+ and inositol polyphoshates. Am J Physiol 7: L219-L225.
18. Mattila P, Majuri ML, Mattila PS, Renkonen R. (1992). TNF alpha-induced expression of endothelial adhesion molecules, ICAM-1 and VCAM-1, is linked to protein kinase C activation. Scand J Immunol 36: 159-165.
19. McDonagh PF, Williams SK. (1984). The preparation and use of fluorescent-protein conjugates for microvascular research. Microvasc Res 27:14-27.
20. Nakagawa K, Miller FN, Sims DE, Lentsch AB, Miyazaki M, Edwards MJ. (1996). Mechanisms of interleukin-2-induced hepatic toxicity. Cancer Res 56: 507-510.
21. Ohkubo C, Bigos D, Jain R. (1991). Interleukin-2-duced leukocytes adhesion to the normal and tumor microvascular endothelium in vivo and its inhibition by dextran sulfate: implications for vascular leak syndrome. Cancer Res 51:1561-1563.
22. Palmer PA, Vinke J, Evers P, Pourreau C, Oskam R, Roest G, Vlems F, Becker L, Loriaux E, Franks CR. (1992). Continuous infusion of recombinant interleukin-2 with or without autologous lymphokine activated killer cells for the treatment of advanced renal cell carcinoma. Eur J Cancer 28:1038-1044.
23. Partridge CA, Horvath CJ, Del Vecchio PJ, Phillips PG, Malik AB. (1992). Influence of extracellular matrix in tumor necrosis factor-induced increase in endothelial permeability. Am J Physiol 263:L627-L633.
24. Pfau S, Leitenberg D, Rinder H, Smith BR, Pardi R, Bender JR. (1995). Lymphocyte adhesion-dependent calcium signalling in human endothelial cells. J Cell Biol 128:969-978.
25. Remick DG, Nguyen DT, Eskandari MK, Kunkel SL. (1991). Interleukin-2 induces tumor necrosis factor gene expression in vivo. Immunol Invest 20:395-405.
26. Rotrosen D, Gallin JI. (1986). Histamine type I receptor occupancy increases endothelial cytosolic calcium, reduces f-actin, and promotes albumin diffusion across cultured endothelial monolayers. J Cell Biol 103:2379-2387.
27. Royall JA, Berkow RL, Beckman JS, Cunningham MK, Matalon S, Freeman BA. (1989). Tumor necrosis factor and interleukin-1 α increase vascular endothelial permeability. Am J Physiol 1:L399-L410.
28. Smith WB, Gamble R, dark-Lewis I, Vadas MA. (1993). Chemotactic desensitization of neutrophils demonstrates interleukin-8 (IL-8)-dependent and IL-8-independent mechanisms of transmigration through cytokine-activated endothelium. Immunology 78:491-497.
29. Stasek JE, Patterson CE, Garcia JGN. (1992). Protein kinase C phosphorylates caldesmon 77 and vimentin and enhances albumin permeability across cultured bovine artery endothelial cell monolayers. J Cell Physiol 153:62-75.
30. Wheatley E, Vincent P, McKeown-Longo P, Saba T. (1993). Effect of fibronectin on permeability of normal and TNF-treated lung endothelial cell monolayers. Am J Physiol 264:R90-R96.
31. Yurchenco PD, Schittny JC. (1990). Molecular architecture of basement membranes. FASEB J 4:1577-1590.
32. Zhao D, Luini W, Bernasconi S, Diomede L, Salmona M, Mantovani A, Sozzani S. (1995). Phosphatidic acid and lysophosphatidic acid induce haptotactic migration of human monocytes. J Biol Chem 270: 25549-25556.
33. Ziegelstein RC, Corda S, Pili R, Passaniti A, Lefer D, Zweir JL, Fraticelli A, Capogrossi MC. (1994). Initial contact and subsequent adhesion of human neutrophils or monocytes to human aortic endothelial cells releases an endothelial intracellular calcium store. Circulation 90:1899-1907.