Cytokine and protease glycosylation as a regulatory mechanism in inflammation and autoimmunity

Advances in Experimental Medicine and Biology

Volumn 435, Issue , 1998, Pages 133-143

  Van Den Steen, Philippe ^a   Rudd, Pauline M ^b   Dwek, Raymond A ^b   Van Damme, Jo ^a   Opdenakker, Ghislain ^a,b  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; PROTEINASE;

ANIMAL; AUTOIMMUNITY; EXTRACELLULAR MATRIX; GLYCOSYLATION; HUMAN; IMMUNOLOGY; INFLAMMATION; METABOLISM; REVIEW;

ANIMALS; AUTOIMMUNITY; CYTOKINES; ENDOPEPTIDASES; EXTRACELLULAR MATRIX; GLYCOSYLATION; HUMANS; INFLAMMATION;

EID: 0031602226     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-5383-0_13     Document Type: Article

References (47)

1. Adolf, G.R., Kalsner, I., Ahorn, H., Maurer-Fogy, I., and Cantell, K., 1991, Natural human interferon-α2 is O-glycosylated, Biochem. J. 276: 511-518.
2. Cebon, J., Nicola, N., Ward, M., Gardner, I., Dempsey, P., Layton, J., Durhrsen, U., Burgess, A.W., Nice, E., and Morstyn, G., 1990, Granulocyte-macrophage colony stimulating factor from human lymphocytes. The effect of glycosylation on receptor binding and biological activity, J. Biol. Chem. 265:4483-4491.
3. Cerretti, D.P., Kozlosky, C.J., Mosley, B., Nelson, N., Van Ness, K., Greenstreet, T.A., March, C.J., Kronheim, S.R., Druck, T., Cannizzaro, L.A., Huebner, K., and Black, R.A., 1992, Molecular cloning of the interleukin-1β converting enzyme, Science 256:97-100.
4. de Munk, G.A., Parkinson, J.F., Groeneveld, E., Bang, N.U., and Rijken, D.C., 1993, Role of the glycosaminoglycan component of thrombomodulin in its acceleration of the inactivation of single-chain urokinase-type plasminogen activator by thrombin, Biochem. J. 290:655-659.
5. K., 1991, Clearing up glycoprotein hormones, Cell 67:1029-1032.
6. Dijkmans, R., Heremans, H., and Billiau, A., 1987, Heterogeneity of chinese hamster ovary cell-produced recombinant interferon-g, J. Biol. Chem. 262:2528-2535.
7. Drickamer, K., 1991, Clearing up glycoprotein hormones, Cell 67:1029-1032.
8. Fleer, R., Chen, X.J., Amellal, N., Yeh, P., Fournier, A., Guinet, F., Gault, N., Faucher, D., Folliard, F., Fukuhara, H., and Mayaux, J.-F., 1991, High-level secretion of correctly processed recombinant human interleukin-1 beta in Kluyveromyces lactis, Gene 107:285-295.
9. George, A.J.T., 1994, Surface-bound cytokines -a possible effector mechanism in bacterial immunity?, Immunol. Today 15:88-89.
10. Hasegawa, M., 1993, A thermodynamic model for denaturation of granulocyte colony-stimulating factor: O-linked sugar chain suppresses not the triggering deprotonation but the succeeding denaturation, Biochim. Biophys. Acta. 1203:295-297.
11. Ishii, K., Yamagami, S., Tanaka, H., Motoki, M., Suwa, Y. and Endo, N., 1995, Full active baculovirus-expressed human monocyte chemoattractant protein I with the intact N-terminus, Biochem. Biophys. Res. Comm. 206:955-961.
12. Kodama, S., Tsujimoto, M., Tsuruoka, N., Sugo, T., Endo, T., and Kobata, A., 1993, Role of sugar chains in the in-vitro activity of recombinant human interleukin 5, Eur. J. Biochem. 211:903-908.
13. Kunimoto, D.Y., Allison, K.C., Watson, C., Fuerst, T., Armstrong, G.D., Paul, W., and Strober, W., 1991, High-level production of murine interleukin-5 (IL-5) utilising recombinant baculovirus expression. Purification of the rill-5 and its use in assessing the biologic role of IL-5 glycosylation, Cytokine 3:224-230.
14. Livi, G.P., Ferrara, A.A., Roskin, R., Simon, Pl., and Young, Pr., 1990, Secretion of N-glycosylated human recombinant interleukin-1 alpha in Saccharomyces cerevisiae. Gene 88:297-301.
15. Livi, G.P., Lillquist, J.S., Miles, L.M., Ferrara, A., Sathe, G.M., Simon, Pl., Meyers, C.A., Gorman, J.A., Young, Pr., 1991, Secretion of N-glycosylated interleukin-1 beta in Saccharomyces cerevisiae using a leader peptide from Candida albicans. Effect of N-glycosylation on biological activity, J. Biol. Chem. 266:15348-15355.
16. Lucas, R., Magez, S., De Leys, R., Fransen, L., Scheerlinck, J.P., Rampelberg, M., Sablon, E., and De Baetselier, P., 1994, Mapping the lectin-like activity of tumor necrosis factor, Science 263:814-817.
17. Marchese, E., Vita, N., Maureaud, T., Ferrara, P., 1990, Separation by cation-exchange high-performance liquid chromatography of three forms of Chinese hamster ovary cell-derived recombinant human interleukin-2, J. Chromatogr. 504:351-358.
18. Masure, S., Nys, G., Fiten, P., Van Damme, J., and Opdenakker, G., 1993, Mouse gelatinase B: cDNA cloning, regulation of expression and glycosylation in WEHI-3 macrophages and gene organisation, Eur. J. Biochem. 218:129-141.
19. Masure, S., and Opdenakker, G. 1989, Cytokine-mediated proteolysis in tissue remodelling, Experientia 45:542-549.
20. Michaëlsson, E., Malmstrom, V., Reis, S., Engstrom, A., Burkhardt, H., and Holmdahl, R., 1994, T cell recognition of carbohydrates on type II collagen, J. Exp. Med. 180:745-749.
21. Mori, K., Dwek, R.A., Downing, A.K., Opdenakker, G., and Rudd, P.M., 1995, The activation of type 1 and type 2 plasminogen by type 1 and type 2 tissue plasminogen activator, J. Biol. Chem. 270:3261-3267.
22. Mutsaers, J.H.G.M., Kamerling, J.P., Devos, R., Guisez, Y., Fiers, W., and Vliegenthart, J.F.G., 1986, Structural studies of the carbohydrate chains of γ-interferon, Eur. J. Biochem. 156:651-654.
23. Naim, H.Y., and Lentze, M.J., 1992, Impact of O-glycosylation on the function of human intestinal lactase-phlorizin hydrolase. Characterization of glycoforms varying in enzyme activity and localization of O-glycoside addition, J. Biol. Chem. 267:25494-25504.
24. Nissen, C., Dalle Carbonare, V., and Moser, Y., 1994, In vitro comparison of the biological potency of glycosylated versus nonglycosylated rG-CSF, Drug invest. 7:346-352.
25. Oh-eda, M., Hasegawa, M., Hattori, K., Kuboniwa, H., Kojima, T., Orita, T., Tomonou, K., Yamazaki, T., and Ochi, N., 1990, O-linked sugar chain of human granulocyte colony-stimulating factor protects it against polymerization and denaturation allowing it to retain its biological activity, J. Biol. Chem. 265:11432-11435.
26. Opdenakker, G., Cabeza-Arvelais, Y., and Van Damme, J., 1989, Interaction of interferon with other cytokines, Experientia 45:513-520.
27. Opdenakker, G., Rudd, P.M., Ponting, C.P., and Dwek, R.A., 1993, Concepts and principles of glycobiology, FASEB J. 7:1330-1337.
28. Opdenakker, G., Rudd, P.M., Wormald, M., Dwek, R.A., and Van Damme, J., 1995, Cells regulate the activities of cytokines by glycosylation, FASEB J. 9:453-457.
29. Opdenakker, G., and Van Damme, J., 1992, Cytokines and proteases in invasive processes: molecular similarities between inflammation and cancer, Cytokine 4:251-258.
30. Opdenakker, G., and Van Damme J., 1994, Cytokine-induced proteolysis in autoimmune diseases, Immunol. Today 15:104-107.
31. Opdenakker, G., Van Damme, J., Bosman, F., Billiau, A., and De Somer, P., 1986, Influence of carbohydrate side-chains on activity of tissue-type plasminogen activator, Proc. Soc. Exp. Biol. Med. 182:248-257.
32. Parekh, R.B., Dwek, R.A., Thomas, J.R., Opdenakker, G., Rademacher, T.W., Wittwer, A.J., Howard, S.C., Nelson, R., Siegel, N.R., Jennings, M.G., Harakas, N.K., and Feder, J., 1989, Cell-type-specific and site-specific N-glycosylation of type I and type II human tissue plasminogen activator, Biochemistry 28:7644-7662.
33. Parekh, R.B., Dwek, R.A., Rademacher, T.W., Opdenakker, G., Van Damme, J., 1992, Glycosylation of interleukin-6 from normal human blood mononuclear cells, Eur. J. Biochem. 203:135-141.
34. Parkinson, J.F., Vlahos, C.J., Yan, S.C., and Bang, N.U., 1992, Recombinant human thrombomodulin. Regulation of cofactor activity and anticoagulant function by a glycosaminoglycan side chain, Biochem. J. 283:151-157.
35. Pos, O., van der stelt, M.E., Wolbink, G.J., Nijsten, M.W., van der Tempel, G.L., and van Dijk, W., 1990, Changes in the serum concentration and the glycosylation of human alpha 1-acid glycoprotein and alpha 1-protease inhibitor in severely burned persons: relation to interleukin-6 levels, Clin. Exp. Immunol. 82:579-582.
36. Rademacher, T.W., Parekh, R.B., and Dwek, R.A., 1988, Glycobiology, Ann. Rev. Biochem. 57:785-838.
37. Riske, F.J., Cullen, B.R., Chizzonite, R., 1991, Characterisation of human interferon-gamma and human interleukin-2 from recombinant mammalian cell lines and peripheral blood lymphocytes, Lymphokine and Cytokine Res. 10:213-218.
38. Rudd, P.M., Joao, H.C., Coghill, E., Fiten, P., Saunders, M.R., Opdenakker, G., and Dwek, R.A., 1994, Glycoformsmodify the dynamic stability and functional activity af an enzyme. Biochemistry 33:17-22.
39. Rudd, P.M., Woods, R.J., Wormald, M.R., Opdenakker, G., Downing, A.K., Campbell, I.D., and Dwek, R.A., 1995, The effects of variable glycosylation on the functional activities of ribonuclease, plasminogen and tissue plasminogen activator, Biochim. Biophys. Acta 1248:1-10.
40. Sherblom, A.P., Sathyamoorthy, N., Decker, J.M., and Muchmore, A.V., 1989, IL-2, a lectin with specificity for high-mannose glycopeptides, J. Immunol. 143:939-944.
41. Tanner, J.E., Goldman, N.D., and Tosato, G., 1990, Biochemical and biological analysis of human interleukin 6 expressed in rodent and primate cells, Cytokine 2:363-374.
42. Thor, G., Brian, A.A., 1992, Glycosylation variants of murine interleukin-4: evidence for different functional properties, Immunology 75:143-149.
43. Thornberry, N.A., Bull, H.G., Calaycay, J.R., Chapman, K.T., Howard, A.D., Kostura, M.J., Miller, D.K., Molineaux, S.M., Weidner, J.R., Aunins, J., Elliston, K.O., Ayala, J.M., Casano, F.J., Chin, J., Ding, G. J.-F., Egger, L.A., Gaffney, E.P., Limjuco, G., Palyha, O.C., Raju, S.M., Rolando, A.M., Salley, J.P., Yamin, T.-T., Lee, T.D., Shivery, J.E., MacCross, M., Mumford, R.A., Schmidt, J.A., and Tocci, M.J., 1992, A novel heterodimeric cysteine protease is required for interleukin-1ß processing in monocytes, Nature 356:768-774.
44. Tominaga, A., Takahashi, T., Kikuchi, Y., Mita, S., Naomi, S., Harada, N., Yamaguchi, N., and Takatsu, K., 1990, Role of carbohydrate moiety of IL-5. Effect of tunicamycin on the glycosylation of IL-5 and the biologic activity of deglycosylated IL-5, J. Immunol. 144:1345-1352.
45. Van Damme, J., De Ley, M., Opdenakker, G., Billiau, A., De Somer, P., and Van Beeumen, J., 1985, Homogeneous interferon-inducing 22K factor is related to endogenous pyrogen and interleukin-1, Nature 314:266-268.
46. Wittwer, A.J., Howard, S.C., Carr, L.S., Harakas, N.K., Feder, J., Parekh, R.B., Rudd, P.M., Dwek, R.A., Rademacher, T.W., 1989, Effects of N-glycosylation on in vitro activity of Bowes melanoma and human colon fibroblast derived tissue plasminogen activator, Biochemistry 28:7662-7669.
47. Ziltener, H.J., 1993, Glycosylation does not affect in vitro biological activity of interleukin-3, Cytokine 5:291-297.