Biological Effects of Prolonged Exposure to ELF Electromagnetic Fields in Rats: III. 50 Hz Electromagnetic Fields

Bioelectromagnetics

Volumn 19, Issue 1, 1998, Pages 57-66

  Zecca, L ^a   Mantegazza, C ^a   Margonato, V ^b   Cerretelli, P ^a   Caniatti, M ^b   Piva, F ^b   Dondi, D ^b   Hagino, N ^c  

^a INSTITUTE OF BIOMEDICAL TECHNOLOGIES   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Brain receptors; Electric and magnetic fields; Hematology; Histology; Neurotransmitters; Serum chemistry

Indexed keywords

BONE; ELECTROMAGNETIC FIELDS; RATS;

BIOLOGICAL EFFECTS; BONE MARROW; BRAIN RECEPTORS; ELECTRIC AND MAGNETIC FIELDS; FIELD STRENGTHS; HAEMATOLOGY; LYMPH NODE; NEUROTRANSMITTER; PINEAL GLAND; SERUM CHEMISTRY;

HISTOLOGY;

ANIMALIA;

3,4 DIHYDROXYPHENYLACETIC ACID; 5 HYDROXYINDOLEACETIC ACID; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; BIOGENIC AMINE; DOPAMINE; DOPAMINE 2 RECEPTOR; HOMOVANILLIC ACID; MU OPIATE RECEPTOR; SEROTONIN;

ANIMAL; ARTICLE; BODY WEIGHT; BRAIN; DRUG EFFECT; ELECTROMAGNETIC FIELD; MALE; METABOLISM; MOTOR ACTIVITY; PINEAL BODY; RADIATION EXPOSURE; RADIATION RESPONSE; RAT; SPRAGUE DAWLEY RAT; TIME;

3,4-DIHYDROXYPHENYLACETIC ACID; ANIMALS; BIOGENIC AMINES; BODY WEIGHT; BRAIN; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTROMAGNETIC FIELDS; HOMOVANILLIC ACID; HYDROXYINDOLEACETIC ACID; MALE; MOTOR ACTIVITY; NEUROTRANSMITTER AGENTS; PINEAL GLAND; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D2; RECEPTORS, OPIOID, MU; SEROTONIN; TIME FACTORS;

EID: 0031601555     PISSN: 01978462     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-186X(1998)19:1<57::AID-BEM7>3.0.CO;2-3     Document Type: Article

References (47)

1. Armitage P, Berry G (1987): "Statistical methods in medical research, 2nd Ed." Oxford: Blackwell Scientific Publications.
2. Bastuji-Garin S, Richardsons S, Zittoun R (1990): Acute leukemia in workers exposed to electromagnetic fields. Br J Cancer 26(11/ 12):1119-1120.
3. Bradford MM (1976): A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
4. Brown GM, Grata LT, Harvey L, Tsui MW, Pang SF (1983): Differential regulation of the 24 hr pattern of serum melatonin and N-acetyl-serotonin. In Axelrod J, Fraschini F, Velo GP (eds): "The pineal gland and its endocrine role" New York and London: Plenum Press, pp 243-256.
5. Coelho AM, Roger WR Jr, Smith HD (1995): Effects of current exposure to 60 Hz electric and magnetic fields on the social behavior of baboons. Bioelectromagnetics Supplement 3:71-92.
6. Dondi D, Limonta P, Maggi R, Piva F (1992): Effects of ovarian hormones on brain opioid binding sites in castrated female rats. Am J Physiol 263:E507-E511.
7. Feychting M, Ahlbohm A (1993): Magnetic fields and cancer in children residing near Swedish high-voltage power lines. Am J Epidemiol 138:467-481.
8. Garland FC, Shaw E, Gorham ED, Garland CF, White MR, Shinsheimer PJ (1990): Incident of leukemia in occupations with potential exposure to electromagnetic field in United States Navy personnel. Am J Epidemiol 132:293-303.
9. Grisset JD (1979): Enhanced growth in pubescent male primates chronically exposed to extremely low frequency fields. In: Biological effects of extremely low frequency electromagnetic fields. Springfield, IL: 18th Annual Handford Life Sci, pp 346-361. Published by Technical Information Center US dept of Energy (DOE).
10. 3H] spiperone binding assay in vivo studies of effects of a reversed of test magnetic field on the development of dopamine D2 receptors in the striatum of the rat brain. Proc. 1992 Annu Rev, U.S. Dept of Energy, Electric Power Research Institute A-28.
11. Jain NC (1986): Normal values in blood of laboratory, fur-bearing, and miscellaneous zoo, domestic, and wild animals. In Jain NC (ed.): "Schalm's Veterinary Hematology" 4th ed. Philadelphia: Lea & Febiger, pp 274-349.
12. Kato M, Honma K, Shigemitsu T, Shiga Y (1993): Effects of exposure to a circularly polarized 50 Hz magnetic field on plasma and pineal melatonin levels in rats. Bioelectromagnetics 14:97-106.
13. Kato M, Honma K, Shigemitsu T, Shiga Y (1994): Circularly polarized, sinusoidal, 50 Hz magnetic field exposure does not influence plasma testosterone levels of rats. Bioelectromagnetics 15:513-518.
14. Kavaliers M, Ossenkopp KP (1991): Opioid systems and magnetic field effects in the land snail. Cepaea memoralis. Biol Bull 180:301-309.
15. Kavaliers M, Ossenkopp KP (1993): Repeated naloxone treatments and exposure to weak 60-Hz magnetic fields have "analgesic" effects in snails. Brain Res 620:159-162.
16. Kavet R, Michael Silva J, Thornton D (1992): Magnetic field exposure assessment for adult residents of Maine who live near and far away from overhead transmission lines. Bioelectromagnetics 13:35-55.
17. Lai H, Carino MA, Horita A, Guy AW (1993): Effects of a 60 Hz magnetic field on central cholinergic system of the rat. Bioelectromagnetics 14:5-15.
18. Loomis DP, Savitz DA, Ananth CV (1994): Breast cancer mortality among female electrical workers in the United States. J Natl Cancer Inst 86:921-924.
19. Lowry OH, Rosebroug NJ, Farr AL, Randall J (1951): Protein measurement with the folin phenol reagent. J Biol Chem 193:256-275.
20. Mader DL, Barrow DA, Donnelly KE, Sceer RR, Sheror MD (1990): A simple model for calculating residential 60 Hz magnetic fields. Bioelectromagnetics 11:283-296.
21. Maggi R, Dondi D, Rovati GE, Martini L, Piva F, Limonta P (1993): Binding characteristic hypothalamic mu opioid receptors throughout the estrous cycle in the rat. Neuroendocrinology 58:366-372.
22. Mansour A, Lewis ME, Khachaturian H, Akil H, Watson SJ (1986): Pharmacological and anatomical evidence of selective μ δ and χ opioid receptor binding in rat brain. Brain Res 399:69-79.
23. Margonato V, Veicsteinas A, Conti R, Nicolini P, Cerretelli P (1993): Biologic effects of prolonged exposure to ELF electromagnetic fields in rats. I. 50 Hz electric fields. Bioelectromagnetics 14:479-493.
24. Margonato V, Nicolini P, Conti R, Zecca L, Veicsteinas A, and Cerretelli P (1995): Biologic effects of prolonged exposure to ELF electromagnetic fields in rats: II. 50 Hz magnetic fields. Bioelectromagnetics 16:343-355.
25. Marino A (1990): Meta-analysis of multi-generational studies of mice exposed to power-frequency electric fields. Journal of Bioelectricity 9(2):213-231.
26. Munson PJ, Rodbard D (1984): Computerized analysis of ligand binding data: Basic principles and recent development. In Rodbard D, Forti G (eds). Computers in Endocrinology. New York, Raven Press pp: 117-145.
27. 31I. Proc Soc Exp Biol Med 128:807-811.
28. Olsen JH, Nielsen A, Schulgen G (1993): Residence near high-voltage facilities and risk of cancer in children. Br Med J 307:891-895.
29. Paxinos G, Watson C (1986): The rat brain. In stereotaxic coordinates. 2nd Ed. Academic Press.
30. Peters JM, London SJ, Thomas DC, Bowman JD, Sobel E, Chang T (1991): Exposure to residential electric and magnetic fields and risks of children leukemia. Am J Epidemiol 134:923-937.
31. Pfeiffer A, Herz A (1982): Different types of opioid agonists interact distinguishably with mu, delta, and kappa opioid binding sites. Life Sci 31:1355-1358.
32. Reiter RJ (1993): Static and extremely low frequency electromagnetic field exposure: Reported effects on the circadian production of melatonin. J Cell Biochem 51:394-403.
33. Rogers WR, Reiter RJ, Smith HD, Barlow-Walden L (1995): Rapid-onset/offset, variably scheduled 60 Hz electric and magnetic field exposure reduces nocturnal serum melatonin concentration in nonhuman primates. Bioelectromagnetics Supplement 3:119-122.
34. Rovati GE, Rodbard D, Munson PJ (1988): DESIGN: Computerized optimization of experimental design for estimating Kd and Bmax in ligand and heterologous binding to one class of sites. Anal Biochem 174:636-649.
35. Savitz AD, Loomis P (1995): Magnetic Fields exposure in relation to leukemia and brain cancer mortality among Electric utility workers. Am J Epidemiol 141(2):123-134.
36. Seegal RF, Wolpaw JR, Dowman R (1989): Chronic exposure of primate to 60 Hz electric and magnetic fields: II. Neurochemical effects. Bioelectromagnetics 10:289-301.
37. Smith RF, Clarke RL, Justesen DR (1994): Behavioral sensitivity of rats to extremely-low-frequency magnetic fields. Bioelectromagnetics 15:411-426.
38. Sobel E, Davanipour Z, Sulkava R, Erkinjuntti T, Wikstrom J, Henderson VW, Buckwalter G, Bowman JD, Lee P (1995): Occupations with exposure to electromagnetic fields: a possible risk factor for Alzheimer disease. Am J Epidemiol 142(5):515-524.
39. Stuchly MA, McLean JRN, Burnett R, Goddard M, Lecuyer DW, Rej M (1992): Modification of tumor promotion in the mouse skin by exposure to an alternating field. Cancer Lett 65:1-7.
40. 3] nicotine binding sites in developing brain in rats. Neurosci Res 2:387-389.
41. Svedenstål BM, Johanson KJ (1995): Fetal loss in mice exposed to magnetic fields during early pregnancy. Bioelectromagnetics 16:284-289.
42. Theriault G, Goldberg M, Miller AB, Armstrong B, Guenel P, Deadman J, Imbernon E, To T, Chevalier A, Cyr D, Wall C (1994): Cancer risks associated with occupational exposure to magnetic fields among electric utility workers in Ontario and Quebec, Canada, and France: 1970-1989. Am J Epidemiol 139:550-572.
43. Vasquez BJ, Anderson LE, Lowery C, Ross Adey W (1988): Diurnal patterns in brain biogenic amines of rats exposed to 60 Hz electric fields. Bioelectromagnetics 9:229-236.
44. Wertheimer N, Savitz DA, Leeper E (1995): Childhood cancer in relations to indicators of Magnetic Fields from ground current sources. Bioelectromagnetics 16:86-96.
45. Wilson BW, Chess EK, Anderson LE (1986): 60 Hz electric field effects on pineal melatonin rhythms: Time course for onset and recovery. Bioelectromagnetics 7:239-242.
46. Yu MC, Gona AG, Gona O, Al-Rabiai S, Von Hagen S, Cohen E (1993): Effects of 60 Hz electric and magnetic fields on maturation of the rat neopallium. Bioelectromagnetics 14:449-458.
47. Zecca L, Ferrario P, Margonato V, Cerretelli P, Zonta N (1991): Neurotransmitter amino acid variations in striatum of rats exposed to 50 Hz electric fields. Biochim Biophys Acta 1075:1-5.