Determination of encephalomyocarditis vital diabetogenicity by a putative binding site of the viral capsid protein

Diabetes

Volumn 47, Issue 4, 1998, Pages 576-582

  Jun, Hee Sook ^a   Kang, Yup ^a,b   Yoon, Ho Sup ^c   Kim, Ki Hwan ^c   Notions, Abner L ^d   Yoon, Ji Won ^a,b,e  

^a UNIVERSITY OF CALGARY   (Canada)

^b Ajou University School of Medicine   (South Korea)

^c ABBOTT LABORATORIES   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

^e UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN; VP1 PROTEIN, ENCEPHALOMYOCARDITIS VIRUS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETOGENESIS; ENCEPHALOMYOCARDITIS VIRUS; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; VIRUS CELL INTERACTION; VIRUS RECOMBINANT; ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; GENETIC RECOMBINATION; GENETICS; INSULIN DEPENDENT DIABETES MELLITUS; METABOLISM; PANCREAS ISLET; PATHOGENICITY; POINT MUTATION; PROTEIN CONFORMATION; VIROLOGY; VIRUS CAPSID;

ANIMALS; BINDING SITES; CAPSID; CAPSID PROTEINS; DIABETES MELLITUS, TYPE 1; ENCEPHALOMYOCARDITIS VIRUS; ISLETS OF LANGERHANS; MALE; MICE; MODELS, MOLECULAR; POINT MUTATION; PROTEIN CONFORMATION; RECOMBINATION, GENETIC;

EID: 0031596748     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.47.4.576     Document Type: Article

References (28)

1. Subbarao EK, London W, Murphy BR: A single amino acid in PB2 gene of influenza A virus is a determinant of host range. J Virol 67:1761-1764, 1993
2. Rogers GN, Paulson JC, Daniels RS, Skehel JJ, Wilson LA, Wiley DC: Single amino acid substitutions in influenza haemagglutinin change receptor binding specificity. Nature 304:76-78, 1983
3. Zurbriggen A, Thomas C, Yamada M, Roos RP, Fujinami RS: Direct evidence of a role for amino acid 101 of VP-1 in central nervous system disease in Theiler's murine encephalomyelitis virus infection. J Virol 65:1929-1937, 1991
4. Ren RB, Moss EG, Racaniello VR: Identification of two determinants that attenuate vaccine-related type 2 poliovirus. J Virol 65:1377-1382, 1991
5. Caggana M, Chan P, Ramsingh AJ: Identification of a single amino acid residue in the capsid protein VP1 of coxsackievirus B4 that determines the virulent phenotype. Virol 67:4797-1803, 1993
6. Bernhardt G, Harber J, Zibert A, de Crombrugghe M, Wimmer E: The poliovirus receptor identification of domains and amino acid residues critical for virus binding. Virol 203:344-356, 1994
7. Craighead JE, McLane MF: Diabetes mellitus: induction in mice by encephalomyocarditis virus. Science 162:913-914, 1968
8. Boucher DW, Notkins AL: Virus-induced diabetes mellitus. I. Hyperglycemia and hypoinsulinemia in mice infected with encephalomyocarditis virus. J Exp Med 137:1226-1239, 1973
9. Yoon JW, Notkins AL: Virus-induced diabetes mellitus. VI. Genetically determined host differences in the replication of encephalomyocarditis virus in pancreatic beta cells. J Exp Med 143:1170-1185, 1976
10. Yoon JW, Lesniak MA, Fussganger R, Notkins AL: Genetic differences in susceptibility of pancreatic β-cells to virus-induced diabetes mellitus. Nature 264:178-180,1976
11. Yoon JW, Rodrigues MM, Currier C, Notkins AL: Long-term complications of virus- induced diabetes mellitus in mice. Nature 296:566-569, 1982
12. Hirasawa K, Jun HS, Maeda K, Kawaguchi Y, Itagaki S, Mikani T, Baek HS, Doi K, Yoon JW: Possible role of macrophage-derived soluble mediators in the pathogenesis of EMC virus-induced diabetes in mice. J Virol 71:4024-4031, 1997
13. Yoon JW, McClintock PR, Onodera T, Notkins AL: Virus-induced diabetes mellitus. XVIII. Inhibition by a nondiabetogenic variant of encephalomyocarditis virus. J Exp Med 152:878-892, 1980
14. Yoon JW, Wong AK, Bae YS, Eun HM: An apparent deletion of an oligonucleotide detected by RNA fingerprint in the nondiabetogenic B variant of encephalomyocarditis virus is caused by a point mutation. J Virol 62:637-650, 1988
15. Bae YS, Eun HM, Yoon JW; Genomic differences between the diabetogenic and nondiabetogenic variants of encephalomyocarditis virus. Virol 170:282-287, 1989
16. Bae YS, Yoon JW: Determination of diabetogenicity attributable to a single amino acid, Ala-776, on the polyprotein of encephalomyocarditis virus. Diabetes 42:435-443, 1993
17. Jun HS, Kang Y, Notions AL, Yoon JW: Gain or loss of diabetogenicity resulting from a single point mutation in recombinant encephalomyocarditis virus. J Virol 71:9782-9785, 1997
18. Ray UR, Aulakh GS, McClintock PR, Yoon JW, Notions AL: Virus-induced diabetes mellitus. XXV. Difference in the RNA fingerprints of diabetogenic and nondiabetogenic variants of encephalomyocarditis virus. J Gen Virol 64:947-950, 1983
19. Eun HM, Bae YS, Yoon JW: Amino acid differences in the capsid protein, VP1, between diabetogenic and nondiabetogenic variants of encephalomyocarditis virus. Virol 163:369-373, 1988
20. Bae YS, Kang Y, Ohtsuka E, Yoon JW: Development of a recombinant RNA technique for the construction of chimeric RNA with a long poly(C) tract. Nucleic Acids Res 21:2703-2708, 1993
21. Davoren PR: The isolation of insulin from a single cat pancreas. Biochim Biophys Acta 63:150-153, 1962
22. Yoon JW, Morishima T, McClintock PR, Austin M, Notkins AL: Virus-induced diabetes mellitus: Mengo virus infects pancreatic beta cells in strains of mice resistant to the diabetogenic effect of encephalomyocarditis virus. J Virol 50:684-690, 1984
23. Yoon JW, Onodera T, Jenson B, Notions AL: Virus-induced diabetes mellitus. XI. Replication of coxsackie B3 virus in human pancreatic beta cell cultures. Diabetes 27:778-781, 1978
24. Kang Y, Yoon JW: A genetically determined host factor controlling susceptibility to encephalomyocarditis virus-induced diabetes in mice. J Gen Virol 74:1207-1213, 1993
25. Luo M, Vriend G, Kamer G, Minor I, Arnold E, Rossman MG, Boege U, Scraba DG, Duke GM, Palmenberg AC: The atomic structure of Mengo virus at 3.0: A resolution. Science 235:182-191, 1987
26. Bae YS, Eun HM, Pon RT, Giron D, Yoon JW: Two amino acids, Phe-16 and Ala-776, on the polyprotein are most likely responsible for diabetogenicity of encephalomyocarditis virus. J Gen Virol 71:639-645, 1990
27. Rossmann MG, Arnord E, Erickson JW, Frankenberger EA, Griffith JP, Hecht HJ, Johnson JE, Kamer G, Luo M, Mosser AG, Lueckert RR, Sherry B, Vriend G: Structure of human common cold virus and functional relationship to other picornaviruses. Afatare 317:145-153, 1985
28. Inoue H, Hayase Y, Iwai S, Ohtsuka E: Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H. FEBS Lett 215:327-330, 1987