M1 muscarinic agonist treatment reverses cognitive and cholinergic impairments of apolipoprotein E-deficient mice

Journal of Neurochemistry

Volumn 70, Issue 5, 1998, Pages 1991-1997

  Fisher, A ^a   Brandeis, R ^a   Chapman, S ^a   Pittel, Z ^a   Michaelson, D M ^a,b  

^a TEL AVIV UNIVERSITY   (Israel)

^b ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH   (Israel)

Author keywords

Alzheimer's disease; Apolipoprotein E; Cholinergic replacement therapy

Indexed keywords

AF 150S; APOLIPOPROTEIN E; MUSCARINIC M1 RECEPTOR AGONIST; UNCLASSIFIED DRUG; 1 METHYLPIPERIDINE 4 SPIRO (2' METHYLTHIAZOLINE); 1-METHYLPIPERIDINE-4-SPIRO-(2'-METHYLTHIAZOLINE); ACETYLCHOLINESTERASE; CHOLINE ACETYLTRANSFERASE; MUSCARINIC AGENT; PIPERIDINE DERIVATIVE; THIAZOLE DERIVATIVE;

ALZHEIMER DISEASE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLINERGIC SYSTEM; COGNITIVE DEFECT; CONTROLLED STUDY; DEGENERATIVE DISEASE; MALE; MAZE TEST; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SPATIAL MEMORY; TREATMENT OUTCOME; ANIMAL; BRAIN; CHOLINERGIC NERVE; COGNITION; DRUG EFFECT; GENETICS; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; REACTION TIME; SWIMMING;

ANIMALIA;

ACETYLCHOLINESTERASE; ANIMALS; APOLIPOPROTEINS E; BRAIN; CHOLINE O-ACETYLTRANSFERASE; CHOLINERGIC FIBERS; COGNITION; COGNITION DISORDERS; MALE; MAZE LEARNING; MICE; MICE, KNOCKOUT; MUSCARINIC AGONISTS; PIPERIDINES; REACTION TIME; SWIMMING; THIAZOLES;

EID: 0031596743     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70051991.x     Document Type: Article

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