메뉴 건너뛰기




Volumn , Issue 52, 1998, Pages 321-328

Selegiline as immunostimulant - A novel mechanism of action?

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; SELEGILINE; TUMOR NECROSIS FACTOR; CYTOKINE; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 1; MONOAMINE OXIDASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 0031596707     PISSN: 03036995     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-7091-6499-0_33     Document Type: Article
Times cited : (41)

References (40)
  • 1
    • 0027207998 scopus 로고
    • Cytokines in neuronal cell types
    • Bartfai T, Schultzberg M (1993) Cytokines in neuronal cell types. Neurochem Int 22: 435-444
    • (1993) Neurochem Int , vol.22 , pp. 435-444
    • Bartfai, T.1    Schultzberg, M.2
  • 3
    • 0029417080 scopus 로고
    • Interleukin-1-beta and interleukin 6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients
    • Blum-Degen D, Müller Th, Kuhn W, Gerlach M, Przuntek H, Riederer P (1995) Interleukin-1-beta and interleukin 6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients. Neurosci Lett 202: 17-20
    • (1995) Neurosci Lett , vol.202 , pp. 17-20
    • Blum-Degen, D.1    Müller, Th.2    Kuhn, W.3    Gerlach, M.4    Przuntek, H.5    Riederer, P.6
  • 4
    • 0028364696 scopus 로고
    • Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease
    • Boka G, Anglade P, Wallach D, Javoy Agid F, Agid Y, Hirsch EC (1994) Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease. Neurosci Lett 172: 151-154
    • (1994) Neurosci Lett , vol.172 , pp. 151-154
    • Boka, G.1    Anglade, P.2    Wallach, D.3    Javoy Agid, F.4    Agid, Y.5    Hirsch, E.C.6
  • 5
    • 0023864937 scopus 로고
    • Hypothesis: A role for tumor necrosis factor in immune-mediated demyelination and its relevance to multiple sclerosis
    • Brosnan CF, Selmaj K, Raine CS (1988) Hypothesis: a role for tumor necrosis factor in immune-mediated demyelination and its relevance to multiple sclerosis. J Neuroimmunol 18: 87-94
    • (1988) J Neuroimmunol , vol.18 , pp. 87-94
    • Brosnan, C.F.1    Selmaj, K.2    Raine, C.S.3
  • 7
    • 0029609422 scopus 로고
    • Selegiline in Parkinson's disease
    • Calne DB (1995) Selegiline in Parkinson's disease. BMJ 311: 1583-1584
    • (1995) BMJ , vol.311 , pp. 1583-1584
    • Calne, D.B.1
  • 8
    • 0028182783 scopus 로고
    • Lifespan of immunosuppressed NMRI-mice is increased by deprenyl
    • Freisleben HJ, Lehr F, Fuchs J (1994) Lifespan of immunosuppressed NMRI-mice is increased by deprenyl. J Neural Transm [Suppl] 41: 231-236
    • (1994) J Neural Transm [Suppl] , vol.41 , pp. 231-236
    • Freisleben, H.J.1    Lehr, F.2    Fuchs, J.3
  • 9
    • 0027214546 scopus 로고
    • Induction of tumor necrosis factor-alpha mRNA in the brain after peripheral endotoxin treatment: Comparison with interleukin-1 family and interleukin-6
    • Gatti S, Bartfai T (1993) Induction of tumor necrosis factor-alpha mRNA in the brain after peripheral endotoxin treatment: comparison with interleukin-1 family and interleukin-6. Brain Res 624: 291-294
    • (1993) Brain Res , vol.624 , pp. 291-294
    • Gatti, S.1    Bartfai, T.2
  • 10
    • 0028978580 scopus 로고
    • Expression of interleukin-1α, interleukin-1β and interleukin 1 receptor antagonist mRNA in mouse brain: Regulation by bacterial lipopolysaccharide (LPS) treatment
    • Gabellec MM, Griffais R, Fillion G, Haour F (1995) Expression of interleukin-1α, interleukin-1β and interleukin 1 receptor antagonist mRNA in mouse brain: regulation by bacterial lipopolysaccharide (LPS) treatment. Mol Brain Res 31: 122-130
    • (1995) Mol Brain Res , vol.31 , pp. 122-130
    • Gabellec, M.M.1    Griffais, R.2    Fillion, G.3    Haour, F.4
  • 11
    • 0029019640 scopus 로고
    • Neuroprotective therapeutic strategies. Comparison of experimental and clinical results
    • Gerlach M, Riederer P, Youdim MB (1995) Neuroprotective therapeutic strategies. Comparison of experimental and clinical results. Biochem Pharmacol 50: 1-16
    • (1995) Biochem Pharmacol , vol.50 , pp. 1-16
    • Gerlach, M.1    Riederer, P.2    Youdim, M.B.3
  • 12
    • 0022512521 scopus 로고
    • L-deprenyl attenuates stress ulcer formation in rats
    • Glavin GB, Dugani AM, Pinsky C (1986) L-deprenyl attenuates stress ulcer formation in rats. Neurosci Lett 70: 379-381
    • (1986) Neurosci Lett , vol.70 , pp. 379-381
    • Glavin, G.B.1    Dugani, A.M.2    Pinsky, C.3
  • 13
    • 0006023253 scopus 로고
    • Interleukin-1β activation of the central nervous system
    • Rothwell N, Dantzer R (eds) Pergamon Press, Oxford
    • Gottschall PE, Komaki G, Arimura A (1991) Interleukin-1β activation of the central nervous system. In: Rothwell N, Dantzer R (eds) Interleukin in the brain. Pergamon Press, Oxford, pp 27-49
    • (1991) Interleukin in the Brain , pp. 27-49
    • Gottschall, P.E.1    Komaki, G.2    Arimura, A.3
  • 14
    • 0030021001 scopus 로고    scopus 로고
    • Adrenalectomy enhances proinflammatory cytokines gene expression, in the spleen, pituitary and brain of mice in response to lipopolysaccharide
    • Goujon E, Parnet P, Laye S, Combe C, Dantzer R (1996) Adrenalectomy enhances proinflammatory cytokines gene expression, in the spleen, pituitary and brain of mice in response to lipopolysaccharide. Mol Brain Res 36: 53-62
    • (1996) Mol Brain Res , vol.36 , pp. 53-62
    • Goujon, E.1    Parnet, P.2    Laye, S.3    Combe, C.4    Dantzer, R.5
  • 16
    • 0026024226 scopus 로고
    • Interleukin-6 improves the survival of mesencephalic catecholaminergic and septal cholinergic neurons from postnatal, two-week-old rats in cultures
    • Hama T, Kushima Y, Miyamoto M, Kubota M, Takei N, Hatanaka H (1991) Interleukin-6 improves the survival of mesencephalic catecholaminergic and septal cholinergic neurons from postnatal, two-week-old rats in cultures. Neuroscience 40: 445-452
    • (1991) Neuroscience , vol.40 , pp. 445-452
    • Hama, T.1    Kushima, Y.2    Miyamoto, M.3    Kubota, M.4    Takei, N.5    Hatanaka, H.6
  • 17
    • 0024366885 scopus 로고
    • Tumor necrosis factor identified in multiple sclerosis brain
    • Hofman FM, Hinton DR, Johnson K, Merrill JE (1989) Tumor necrosis factor identified in multiple sclerosis brain. J Exp Med 170: 607-612
    • (1989) J Exp Med , vol.170 , pp. 607-612
    • Hofman, F.M.1    Hinton, D.R.2    Johnson, K.3    Merrill, J.E.4
  • 18
    • 0027506423 scopus 로고
    • Cytokine production by peripheral blood monocytes/macrophages in multiple sclerosis patients
    • Imamura K, Suzumura A, Hayashi F, Marunouchi T (1993) Cytokine production by peripheral blood monocytes/macrophages in multiple sclerosis patients. Acta Neurol Scand 87: 281-285
    • (1993) Acta Neurol Scand , vol.87 , pp. 281-285
    • Imamura, K.1    Suzumura, A.2    Hayashi, F.3    Marunouchi, T.4
  • 19
    • 0025788885 scopus 로고
    • Cytokines and endocrine function: An interaction between the immune and neuroendocrine systems
    • Imura H, Fukata J, Mori T (1991) Cytokines and endocrine function: an interaction between the immune and neuroendocrine systems. Clin Endocrinol 35: 107-115
    • (1991) Clin Endocrinol , vol.35 , pp. 107-115
    • Imura, H.1    Fukata, J.2    Mori, T.3
  • 20
    • 0025332019 scopus 로고
    • Organoselenides as potential immunostimulants and inducers of interferon gamma and other cytokines in human peripheral blood leukocytes
    • Inglot AD, Zielinska Jenczylik J, Piasecki E, Syper L, Mlochowski J (1990) Organoselenides as potential immunostimulants and inducers of interferon gamma and other cytokines in human peripheral blood leukocytes. Experientia 46: 308-311
    • (1990) Experientia , vol.46 , pp. 308-311
    • Inglot, A.D.1    Zielinska Jenczylik, J.2    Piasecki, E.3    Syper, L.4    Mlochowski, J.5
  • 21
    • 0028981609 scopus 로고
    • Rationale for (-)deprenyl (selegiline) medication in Parkinson's disease and in prevention of age-related nigral changes
    • Knoll J (1995) Rationale for (-)deprenyl (selegiline) medication in Parkinson's disease and in prevention of age-related nigral changes. Biomed Pharmacother 49: 187-195
    • (1995) Biomed Pharmacother , vol.49 , pp. 187-195
    • Knoll, J.1
  • 22
    • 0029414748 scopus 로고
    • Neuroimmune mechanisms in Parkinson's disease
    • Kuhn W, Müller Th (1995) Neuroimmune mechanisms in Parkinson's disease. J Neural Transm [Suppl] 46: 217-228
    • (1995) J Neural Transm [Suppl] , vol.46 , pp. 217-228
    • Kuhn, W.1    Müller, Th.2
  • 23
    • 0027298505 scopus 로고
    • Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta
    • Lee SC, Liu W, Dickson DW, Brosnan CF, Berman JW (1993) Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta. J Immunol 150: 2659-2667
    • (1993) J Immunol , vol.150 , pp. 2659-2667
    • Lee, S.C.1    Liu, W.2    Dickson, D.W.3    Brosnan, C.F.4    Berman, J.W.5
  • 24
    • 0029610011 scopus 로고
    • The inflammatory response system of brain: Implications for therapy of Alzheimer and other neurodegenerative diseases
    • McGeer PL, McGeer EG (1995) The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases. Brain Res Rev 21: 195-218
    • (1995) Brain Res Rev , vol.21 , pp. 195-218
    • McGeer, P.L.1    McGeer, E.G.2
  • 25
    • 0028171374 scopus 로고
    • Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from parkinsonian patients
    • Mogi M, Harada M, Kondo T, Riederer P, Inagaki H, Minami M, Nagatsu T (1994a) Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from parkinsonian patients. Neurosci Lett 180: 147-150
    • (1994) Neurosci Lett , vol.180 , pp. 147-150
    • Mogi, M.1    Harada, M.2    Kondo, T.3    Riederer, P.4    Inagaki, H.5    Minami, M.6    Nagatsu, T.7
  • 26
    • 0028178281 scopus 로고
    • Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients
    • Mogi M, Harada M, Riederer P, Narabayashi H, Fujita K, Nagatsu T (1994b) Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients. Neurosci Lett 165: 208-210
    • (1994) Neurosci Lett , vol.165 , pp. 208-210
    • Mogi, M.1    Harada, M.2    Riederer, P.3    Narabayashi, H.4    Fujita, K.5    Nagatsu, T.6
  • 28
    • 0025012838 scopus 로고
    • Tumor necrosis factor alpha functions in an autocrine manner in the induction of human immunodeficiency virus expression
    • Poli G, Kinter A, Justement JS, Kehrl JH, Bressler P, Stanley S, Fauci AS (1990) Tumor necrosis factor alpha functions in an autocrine manner in the induction of human immunodeficiency virus expression. Proc Natl Acad Sci USA 87: 782-785
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 782-785
    • Poli, G.1    Kinter, A.2    Justement, J.S.3    Kehrl, J.H.4    Bressler, P.5    Stanley, S.6    Fauci, A.S.7
  • 29
    • 0024215195 scopus 로고
    • Tumor necrosis factor mediates myelin damage in organotypic cultures of nervous tissue
    • Selmaj K, Raine CS (1988a) Tumor necrosis factor mediates myelin damage in organotypic cultures of nervous tissue. Ann NY Acad Sci 540: 568-570
    • (1988) Ann NY Acad Sci , vol.540 , pp. 568-570
    • Selmaj, K.1    Raine, C.S.2
  • 30
    • 0023904746 scopus 로고
    • Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro
    • Selmaj K, Raine CS (1988b) Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro. Ann Neurol 23: 339-346
    • (1988) Ann Neurol , vol.23 , pp. 339-346
    • Selmaj, K.1    Raine, C.S.2
  • 31
    • 0023947685 scopus 로고
    • Multiple sclerosis: Effects of activated T-lymphocyte-derived products on organ cultures of nervous tissue
    • Selmaj K, Bradbury K, Chapman J (1988a) Multiple sclerosis: effects of activated T-lymphocyte-derived products on organ cultures of nervous tissue. J Neuroimmunol 18: 255-268
    • (1988) J Neuroimmunol , vol.18 , pp. 255-268
    • Selmaj, K.1    Bradbury, K.2    Chapman, J.3
  • 32
    • 0023915247 scopus 로고
    • Interleukin-1 and interleukin-2 production by peripheral blood mononuclear cells in multiple sclerosis patients
    • Selmaj K, Nowak Z, Tchorzewski H (1988b) Interleukin-1 and interleukin-2 production by peripheral blood mononuclear cells in multiple sclerosis patients. J Neurol Sci 85: 67-76
    • (1988) J Neurol Sci , vol.85 , pp. 67-76
    • Selmaj, K.1    Nowak, Z.2    Tchorzewski, H.3
  • 33
    • 0028855346 scopus 로고
    • Prevention of chronic relapsing experimental autoimmune encephalomyelitis by soluble tumor necrosis factor receptor I
    • Selmaj K, Papierz W, Glabinski A, Kohno T (1995) Prevention of chronic relapsing experimental autoimmune encephalomyelitis by soluble tumor necrosis factor receptor I. J Neuroimmunol 56: 135-141
    • (1995) J Neuroimmunol , vol.56 , pp. 135-141
    • Selmaj, K.1    Papierz, W.2    Glabinski, A.3    Kohno, T.4
  • 34
    • 0028027557 scopus 로고
    • Age-related memory decline and longevity under treatment with selegiline
    • Stoll S, Hafner U, Pohl O, Müller WE (1994) Age-related memory decline and longevity under treatment with selegiline. Life Sci 55: 2155-2163
    • (1994) Life Sci , vol.55 , pp. 2155-2163
    • Stoll, S.1    Hafner, U.2    Pohl, O.3    Müller, W.E.4
  • 35
    • 0029047891 scopus 로고
    • Interleukin-1 beta attenuates excitatory amino acid-induced neurodegeneration in vitro: Involvement of nerve growth factor
    • Strijbos PJ, Rothwell NJ (1995) Interleukin-1 beta attenuates excitatory amino acid-induced neurodegeneration in vitro: involvement of nerve growth factor. J Neurosci 15: 3468-3474
    • (1995) J Neurosci , vol.15 , pp. 3468-3474
    • Strijbos, P.J.1    Rothwell, N.J.2
  • 36
    • 0028917028 scopus 로고
    • Selegiline induces "trophic-like" rescue of dying neurons without MAO inhibition
    • Tatton WG, Ansari K, Ju W, Salo PT, Yu PH (1995) Selegiline induces "trophic-like" rescue of dying neurons without MAO inhibition. Adv Exp Med Biol 363: 15-16
    • (1995) Adv Exp Med Biol , vol.363 , pp. 15-16
    • Tatton, W.G.1    Ansari, K.2    Ju, W.3    Salo, P.T.4    Yu, P.H.5
  • 37
    • 0028889115 scopus 로고
    • Deprenyl reinitiates estrous cycles, reduces serum prolactin, and decreases the incidence of mammary and pituitary tumors in old acyclic rats
    • Thyagarajan S, Meites J, Quadri SK (1995) Deprenyl reinitiates estrous cycles, reduces serum prolactin, and decreases the incidence of mammary and pituitary tumors in old acyclic rats. Endocrinology 136: 1103-1110
    • (1995) Endocrinology , vol.136 , pp. 1103-1110
    • Thyagarajan, S.1    Meites, J.2    Quadri, S.K.3
  • 39
    • 0029320146 scopus 로고
    • Cytokine production in the central nervous system
    • Woodroofe MN (1995) Cytokine production in the central nervous system. Neurology 45: S6-S10
    • (1995) Neurology , vol.45
    • Woodroofe, M.N.1
  • 40
    • 0025062435 scopus 로고
    • Interleukin 6 possibly induced by interleukin 1 beta in the pituitary gland stimulates the release of gonadotropins and prolactin
    • Yamaguchi M, Matsuzaki N, Hirota K, Miyake A, Tanizawa O (1990) Interleukin 6 possibly induced by interleukin 1 beta in the pituitary gland stimulates the release of gonadotropins and prolactin. Acta Endocrinol Copenh 122: 201-205
    • (1990) Acta Endocrinol Copenh , vol.122 , pp. 201-205
    • Yamaguchi, M.1    Matsuzaki, N.2    Hirota, K.3    Miyake, A.4    Tanizawa, O.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.